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GLP-1 Nausea

Are you feeling nauseous after using Mounjaro or Wegovy? Find out how you can keep losing weight without the nausea.

Fast and effective treatments to stop that queasy feeling ruining your day.

Continue your weight loss journey with the GLP-1 agonists without putting up with nausea.

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What you should know about nausea?

GLP-1 medications, like Wegovy and Mounjaro, slow down digestion and make you feel full for longer. While this helps with weight loss, it can also cause nausea as your body adjusts to the slower digestion process.

For most people, nausea improves after a few weeks as their body gets used to the medication. If it persists, speak to your doctor for advice or treatment options, such as ondansetron.

To relieve nausea, try sipping on ginger tea, eating a bland snack like crackers, getting some fresh air, or using over-the-counter anti-nausea medications.

You can manage nausea by:

Taking your medication at a specific time of day (e.g., with food or in the evening).

Eating smaller, more frequent meals.

Avoiding greasy or spicy foods.

Staying hydrated with water or clear fluids.

No, don’t stop taking your medication without consulting your doctor. They may adjust your dose or suggest ways to manage the nausea.

Yes, anti-nausea medications like Ondansetron can help manage symptoms. Speak to your doctor to see if this is a suitable option for you.

While nausea is uncomfortable, it’s usually not harmful and tends to subside over time. However, severe or persistent nausea should be discussed with your doctor.

No, not everyone will experience nausea. Some people may have mild symptoms, while others may not feel nauseous at all.

Additional information

GLP-1 induced nausea

Losing weight comes with plenty of benefits, like lowering your risk of diabetes, heart disease, and even cancer. It can also make everyday activities easier, helping you live life to the fullest. However, weight loss medications, such as semaglutide, can sometimes cause side effects, with nausea being one of the most common.

The good news is that GLP-1 induced nausea usually improves after a few weeks as your body adjusts to the medication. Eating smaller meals throughout the day can also help reduce that queasy feeling.

We’re here to support you on your weight loss journey. If you’d like to learn more or need advice, don’t hesitate to reach out to us at Courier Pharmacy. Let’s work together to help you feel your best!

What is nausea?

Nausea is your body’s way of telling you that something isn’t quite right—a warning sign that you might need to prepare for the possibility of being sick. It’s that uneasy, queasy feeling in your stomach that can make you worry about vomiting. While it’s definitely unpleasant, nausea is actually a protective reflex. It’s your body’s way of trying to get rid of harmful substances in your stomach before they can cause more trouble.

Understanding and managing GLP-1-Induced nausea

GLP-1 medications, such as Wegovy and Mounjaro, have become game-changers for managing weight loss and type 2 diabetes. These medications work by helping your body regulate blood sugar levels and appetite, making it easier to lose weight and maintain better health. However, one of the most common side effects is nausea, which can make the early stages of treatment challenging.

Let’s dive deeper into why this happens and how to manage it effectively so you can stay on track with your health goals.

What causes GLP-1 induced nausea?

GLP-1 (Glucagon-Like Peptide-1) medications mimic a natural hormone in your body that helps control blood sugar and appetite. They work by:

  • Slowing down digestion: Food stays in your stomach longer, which helps you feel full and eat less.
  • Reducing hunger signals: These medications help control cravings by affecting parts of your brain that regulate appetite.

While these effects are great for weight loss, they can also lead to nausea, especially when you first start taking the medication or when your dose is increased. This happens because your stomach and digestive system need time to adjust to the slower digestion process.

How long does the nausea last?

The good news is that nausea from GLP-1 medications is usually temporary. For most people, it improves after a few weeks as the body gets used to the medication. However, the severity and duration of nausea can vary from person to person.

Tips to manage GLP-1 induced nausea

If you’re experiencing nausea, there are several strategies you can try to make things more manageable:

1. Adjust your eating habits

  • Eat smaller meals: Instead of three large meals, aim for 5-6 smaller meals throughout the day.
  • Avoid greasy or spicy foods: These can irritate your stomach and worsen nausea. Stick to bland, easy-to-digest foods like crackers, toast, or bananas.
  • Eat slowly: Take your time when eating to avoid overwhelming your stomach.

2. Stay hydrated

  • Sip on water or clear fluids throughout the day to stay hydrated.
  • Try ginger tea or peppermint tea, which can help soothe nausea naturally.

3. Time your medication

  • Some people find that taking their GLP-1 medication with food or at a specific time of day (like in the evening) can help reduce nausea. Talk to your doctor about the best timing for your doses.

4. Use supportive medications

  • If nausea persists, your doctor may recommend an anti-nausea medication like Ondansetron. This can help block the signals in your brain that cause nausea, making it easier to stick with your treatment plan.

When to talk to your doctor

While nausea is a common side effect, you should contact your doctor if:

  • The nausea is severe and doesn’t improve after a few weeks.
  • You’re unable to eat or drink enough to stay hydrated.
  • You experience additional symptoms like vomiting, dizziness, or abdominal pain.

Your doctor may adjust your dose, recommend changes to your treatment plan, or suggest additional therapies to help you feel better.

Why stick with GLP-1 medications?

Even though nausea can be uncomfortable, the long-term benefits of GLP-1 medications are worth it. These medications not only help with weight loss but also reduce your risk of serious health conditions like type 2 diabetes, heart disease, and more. By managing side effects effectively, you can stay on track with your treatment and enjoy the health benefits it provides.

We’re here to support you

At Courier Pharmacy, we understand that starting a new medication can be overwhelming, especially when side effects like nausea come into play. Our team is here to provide guidance, support, and access to medications like Ondansetron to help you manage symptoms and stay on your weight loss journey.

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Tahir Amin
BSc Pharmacy

Compounding Pharmacist


August 21, 2024
August 21, 2026

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