What is Paracetamol?
Paracetamol is a widely-used medication that acts as an analgesic, or pain reliever. It is commonly taken to ease mild to moderate aches and pains, as well as to reduce high temperatures in individuals aged 10 and over.
Paracetamol is known for its effectiveness in managing pain and fever, which is why it is commonly found in both over-the-counter and prescription painkillers, as well as cold and flu remedies.
It is important to avoid taking paracetamol with other medicines that contain paracetamol. Always make sure to read the Patient Information Leaflets carefully before using any new medication. You can purchase Paracetamol online from courierpharmacy.co.uk after completing an online consultation form.
What is the Active Ingredient in Paracetamol?
The active ingredient in Paracetamol is, of course, paracetamol itself. Each tablet or soluble tablet contains 500mg of paracetamol to effectively relieve pain and reduce fever.
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How Does Paracetamol Work?
Paracetamol works by targeting the central nervous system to help reduce pain. It blocks the pain signals that travel from the spinal cord to the brain, which helps reduce the feeling of pain.
In addition to this, paracetamol helps lower pain by limiting the production of prostaglandins. These are chemicals your body creates in response to pain and fever. By reducing prostaglandin production, paracetamol helps lower both pain levels and body temperature.
Thanks to its combined effects on the central nervous system and prostaglandin levels, paracetamol is commonly used to treat various types of pain, such as headaches, toothaches, period pain, and discomfort from minor injuries or surgery. It is also effective in reducing fever, which makes it a popular choice for managing symptoms of colds, flu, and mild infections.
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What Are the Side Effects of Paracetamol?
Like all medications, paracetamol may cause side effects, although not everyone will experience them. Below are some possible side effects:
Stop taking Paracetamol and seek medical attention if:
- You notice swelling in the hands, feet, ankles, face, lips, or throat, which could make swallowing or breathing difficult. You may also experience an itchy rash, hives, or nettle rash. These symptoms may be signs of an allergic reaction to paracetamol.
- You develop serious skin reactions, although these are rare.
Tell your doctor or pharmacist if any of the following side effects become serious or last more than a few days:
- You experience more infections or bruising than usual. This could be a sign of a blood issue, such as agranulocytosis, neutropenia, or thrombocytopenia, though it is uncommon with paracetamol use.
Reporting Side Effects:
If you experience any side effects, whether or not they are listed here, speak with your doctor or pharmacist. You can also report side effects directly through the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or by searching for "MHRA Yellow Card" in the Google Play or Apple App Store. Reporting side effects helps gather more safety information for this medicine.
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Does Paracetamol Interact with Any Other Medicines?
Paracetamol may interact with certain medications, which could affect its effectiveness or increase the risk of side effects. It's crucial to let your doctor or pharmacist know about all the medications you're taking, including prescription, over-the-counter, and herbal products.
Common Drug Interactions:
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Blood Thinners (Anticoagulants):
- Warfarin: Taking paracetamol regularly with warfarin may raise the risk of bleeding. Occasional use is generally safe, but long-term use should be monitored by a healthcare professional.
-
Medicines for Nausea and Vomiting:
- Metoclopramide and Domperidone: These can increase how quickly paracetamol is absorbed, providing faster relief but potentially raising the risk of side effects.
-
Cholesterol-Lowering Medicines:
- Colestyramine: Can lower the absorption of paracetamol, making it less effective. It's best to space these medications several hours apart.
-
Medicines for Epilepsy:
- Carbamazepine and Phenytoin: These can speed up the breakdown of paracetamol, reducing its effectiveness and possibly raising the risk of liver damage.
-
Antibiotics:
- Flucloxacillin: Combining flucloxacillin with paracetamol could cause a serious blood and fluid imbalance, especially in conditions like severe kidney issues, sepsis, malnutrition, or chronic alcohol use.
- Rifampicin: This antibiotic can make paracetamol less effective.
-
Medicines for Mental Health:
- Monoamine Oxidase Inhibitors (MAOIs): Should be avoided as they may interact with paracetamol and increase side effects.
- Antipsychotics (Phenothiazines): May also increase the risk of side effects.
-
Medicines for Gout:
- Probenecid: May slow the elimination of paracetamol from the body, raising the risk of toxicity.
-
Alcohol:
- Regular alcohol use can increase the risk of liver damage when taking paracetamol.
-
Sedatives and Tranquilizers:
- Paracetamol may interact with medications that depress the central nervous system, enhancing sedative effects.
Important Notes:
- Avoid taking other medications containing paracetamol to prevent exceeding the recommended dose.
- Always consult a healthcare provider before starting or stopping any medications while using paracetamol.
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Paracetamol FAQs
What is Paracetamol?
Paracetamol is a commonly used painkiller and fever reducer. It is an analgesic that is effective for treating mild to moderate pain, such as headaches, toothaches, muscle aches, and high temperatures in people over the age of 10. Paracetamol is included in many over-the-counter and prescription medications, including cold and flu remedies. It is important not to take paracetamol with any other medicine that contains paracetamol. Always read the Patient Information Leaflet before starting any new medication.
What is Paracetamol Used For?
Paracetamol 500mg tablets are used for treating mild to moderate pain in individuals over the age of 10. It helps with conditions such as headaches, period pain, toothaches, joint and muscle pain, and post-surgery pain. Additionally, paracetamol is effective at lowering high temperatures often associated with cold and flu symptoms or mild infections. However, it does not treat infections themselves, so consult a doctor if you suspect an infection.
Can Children Take Paracetamol?
Paracetamol tablets and soluble tablets contain 500mg of active ingredient and should not be given to children under the age of 10. Children aged 10 to 15 can take one tablet every 4 to 6 hours. For children under 10 years, consider using paracetamol in syrup or melt form, as per the recommended dosage for their age.
How Does Paracetamol Work?
Paracetamol works by targeting the central nervous system, reducing the pain signals that travel to the brain. It also reduces the production of prostaglandins, which are chemicals produced by the body in response to pain and fever. By lowering these chemicals, paracetamol effectively decreases pain and body temperature.
How Long Does Paracetamol Take to Work and How Long Does it Last?
Paracetamol typically takes up to an hour to start working, with many people experiencing relief within 30 minutes. Its effects can last between 4 to 6 hours. If you require further relief, consult with a healthcare provider about combining paracetamol with other pain relief options like ibuprofen.
How Often Can You Take Paracetamol?
Paracetamol can be taken every 4 to 6 hours, but you should not exceed 4 doses in a 24-hour period. Always follow the dosage guidelines provided in the Directions section and the Patient Information Leaflet.
What is the Recommended Dose of Paracetamol?
The typical dosage for Paracetamol 500mg tablets is for people over 10 years of age. Always refer to the Directions section and the Patient Information Leaflet for specific dosing instructions.
Can You Take Paracetamol with Ibuprofen?
Yes, paracetamol can be safely taken with ibuprofen. To get the best results, alternate the doses of both medicines. This helps to reduce pain and fever consistently over a longer period.
Can You Take Paracetamol with Naproxen?
It is generally safe to take paracetamol with naproxen, but only for a short period and at the recommended doses. If your pain is not relieved after three days, consult a doctor or pharmacist for guidance.
Can You Take Paracetamol with Codeine?
Yes, paracetamol can be used alongside codeine as long as both medications are taken as directed for a short period. Medicines that combine paracetamol and codeine are available. Do not use codeine continuously for more than three days, as it can be addictive. If your pain persists after three days, consult a healthcare provider.
Can You Take Paracetamol When Pregnant?
Paracetamol is generally considered safe during pregnancy and breastfeeding, but always take the smallest effective dose for the shortest period. Speak to your doctor or pharmacist before taking any medication during pregnancy or while breastfeeding.
How Much Paracetamol is Dangerous?
It's vital to follow the dosage instructions carefully. Taking more than the recommended dose can lead to serious side effects, including liver damage. If you suspect an overdose, seek immediate medical help by going to the nearest accident and emergency (A&E) department.
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