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Sumatriptan 50mg tablets

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Sumatriptan is an effective medication used to treat sudden migraine attacks. It belongs to a group of drugs called triptans, which help relieve migraines by narrowing the blood vessels in the brain and stabilizing brain chemicals linked to migraine pain. Sumatriptan is available in different forms, including tablets and nasal sprays, so you can choose the option that works best for you.

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Sumatriptan 50mg tablets
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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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What is Sumatriptan?

Sumatriptan is a prescription medication classified as a triptan, or 5-HT1 receptor agonist, specifically designed to treat migraines. Migraines are often caused by the temporary widening of blood vessels in the brain, leading to intense headaches and other symptoms such as nausea, vomiting, and sensitivity to light and sound.

Sumatriptan works by narrowing these blood vessels, helping to relieve pain and associated symptoms. However, it is not a preventive treatment and should only be taken once a migraine attack begins. For the best results, take Sumatriptan as soon as you notice the onset of migraine symptoms.

Sumatriptan is available in different forms, including tablets and a nasal spray, offering options to suit individual preferences.

What is the active ingredient in Sumatriptan?

Each Sumatriptan tablet contains sumatriptan succinate as the active ingredient.

What is Sumatriptan Used For?

Sumatriptan is primarily used to treat acute migraine attacks. It helps relieve severe headache pain and associated symptoms such as nausea, vomiting, and sensitivity to light and sound. By narrowing the widened blood vessels in the brain, Sumatriptan works to reduce migraine discomfort. It is important to note that Sumatriptan is not a preventive treatment for migraines. Instead, it is intended for use when an attack has already begun. This medication is ideal for individuals who experience intense and recurring migraines and need effective relief.

How Does Sumatriptan Work?

Sumatriptan acts on serotonin receptors in the brain, helping to constrict blood vessels that widen during a migraine. This action helps relieve pain, reduce nausea, and ease other migraine symptoms. It is not effective for preventing migraines or treating other headaches. If you experience frequent migraines, consult a healthcare professional for alternative treatments.

How to Use Sumatriptan

Always follow your doctor’s or pharmacist’s instructions when taking this medicine. If you are unsure, seek medical advice before use. Recommended Dose:
  • Adults: The typical dose is 50mg at the onset of a migraine, but some individuals may require 100mg.
  • Children and Adolescents (under 18 years): Sumatriptan is not recommended for this age group.
  • Elderly (over 65 years): Sumatriptan is generally not advised for individuals over 65.
  • Patients with Liver Impairment: A doctor may prescribe a lower 50mg dose.
How to Take:
  • Swallow the tablet whole with water as soon as you notice migraine symptoms.
  • Do not chew or crush the tablets.
  • If symptoms persist or return, a second dose may be taken at least two hours after the first.
  • Do not exceed 300mg within 24 hours.
What to Do If You Take Too Much: If you take more Sumatriptan than prescribed, seek immediate medical advice. Overuse may increase the risk of side effects.

Who Should Not Use Sumatriptan?

Do not take Sumatriptan if you:
  • Have a history of heart disease or stroke
  • Have uncontrolled high blood pressure
  • Experience migraines with paralysis or weakness
  • Have liver or kidney disease
  • Are allergic to Sumatriptan or any of its ingredients
Before using Sumatriptan, complete an online consultation form at courierpharmacy.co.uk to ensure it is safe for you

Possible Side Effects of Sumatriptan

Like all medications, Sumatriptan may cause side effects. Common side effects include:
  • Dizziness or drowsiness
  • Flushing or a warm sensation
  • Heaviness or tightness in the chest
  • Nausea
Although rare, serious side effects such as chest pain or heart-related symptoms may occur. Seek medical attention if you experience severe reactions.

Does Sumatriptan Interact with Other Medicines?

Some medications should not be taken with Sumatriptan, while others may increase the risk of side effects. Inform your doctor or pharmacist if you are taking any other medicines, particularly:
  • Ergotamine and Similar Migraine Treatments – Do not take Sumatriptan with these medications. Wait at least 24 hours after stopping ergotamine before taking Sumatriptan, and wait at least 6 hours after taking Sumatriptan before using ergotamine again.
  • Other Triptans/5-HT1 Receptor Agonists – Do not take Sumatriptan alongside medications like naratriptan, rizatriptan, or zolmitriptan. Leave at least 24 hours between treatments.
  • SSRIs and SNRIs (Antidepressants) – Taking Sumatriptan with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) may increase the risk of serotonin syndrome. Symptoms include confusion, sweating, hallucinations, muscle spasms, and a rapid heartbeat. Contact your doctor immediately if you experience these symptoms.
  • MAOIs (Monoamine Oxidase Inhibitors) – Sumatriptan should not be taken within two weeks of using an MAOI medication.
  • St. John’s Wort – This herbal supplement may increase the risk of side effects when taken with Sumatriptan.
If you have any concerns about medication interactions, consult your doctor or pharmacist.

Sumatriptan FAQs

What are triptans used for in migraine relief?

Triptans are medications that treat migraines. They help by narrowing blood vessels in the brain and balancing chemicals that affect pain. If regular painkillers don't work, triptans like Sumatriptan can be an effective alternative. You can find Sumatriptan in both generic forms and as the branded Imigran.

How should Sumatriptan be taken for the best results?

For the best outcome, take Sumatriptan as soon as you notice the signs of a migraine. It usually starts working within 30 minutes. If Sumatriptan doesn't relieve your migraine, other triptans like almotriptan (Almogran) or frovatriptan (Migard) may work better.

What is the difference between generic Sumatriptan and Imigran?

Both generic Sumatriptan and the brand name Imigran contain the same active ingredient—sumatriptan succinate. The main difference is the price; generic Sumatriptan is generally less expensive but just as effective as Imigran.

How is Sumatriptan prescribed and what doses are available?

Sumatriptan is only available with a prescription and comes in two doses: 50mg and 100mg. Most people find 50mg effective, but if it's not enough, the 100mg dose may be prescribed for more severe migraines. Your doctor will help you choose the best dose.

What other migraine relief medications are available?

Besides Sumatriptan, other treatments include triptans such as Migard (frovatriptan) 2.5mg tablets, Imigran nasal sprays (10mg & 20mg), and wafer melts like Maxalt Melt (rizatriptan) 10mg.

What over-the-counter options are available for migraines?

Some over-the-counter medications that can help with migraine pain and nausea include paracetamol, ibuprofen, aspirin, and Buccastem M for nausea.

What are the common side effects of Sumatriptan?

Common side effects may include pressure in the chest, throat, or body, unusual sensations like numbness, tingling, warmth or cold, nausea, drowsiness, dizziness, and temporary increases in blood pressure. These effects typically go away quickly but should still be monitored.

What should I do if I experience severe side effects from Sumatriptan?

If you experience severe or long-lasting side effects, such as intense chest pain, seek medical help immediately. Also, if you feel pain or tightness in your chest that doesn't go away, contact a healthcare provider right away.

What are the warnings associated with Sumatriptan?

Sumatriptan should not be used if you have a history of strokes, serious circulation problems, or heart conditions like angina or heart attacks. It is also not suitable for people with high blood pressure or severe liver issues. Speak to your GP before using Sumatriptan if you are a heavy smoker, over 40, or have gone through menopause.

When should I avoid using Sumatriptan?

Avoid Sumatriptan if you're allergic to it or any of its ingredients, have high blood pressure, severe liver problems, or are taking medications like ergotamine or MAO inhibitors.

For more information, refer to the Sumatriptan Patient Information Leaflet or speak with your doctor or pharmacist. You can also purchase Sumatriptan online at courierpharmacy.co.uk after completing a quick online consultation form.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.524.pdf

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Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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