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Metronidazole 400mg Tablets

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Metronidazole is a widely prescribed antibiotic used to treat bacterial vaginosis (BV). BV occurs when the natural balance of bacteria in the vagina is disrupted, causing symptoms like unusual discharge and a fishy odor. Metronidazole works by targeting and reducing the overgrowth of harmful bacteria responsible for BV, helping restore a healthy bacterial balance and relieve symptoms.

Metronidazole is usually taken as oral tablets twice a day for seven days, or as a topical gel applied directly to the vagina. It’s important to complete the full course of treatment to fully clear the infection and reduce the chance of it coming back.

To purchase Metronidazole online, complete the online consultation form at courierpharmacy.co.uk.

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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What is Metronidazole 400mg?

Metronidazole 400mg is a medication commonly used to treat bacterial vaginosis (BV), a common vaginal infection caused by an imbalance in the natural bacteria in the vagina. BV can cause symptoms such as abnormal vaginal discharge, unpleasant odor, itching, and discomfort.

Metronidazole 400mg is usually taken as oral tablets, typically twice a day for seven days when treating BV. The medication works by targeting and eliminating the overgrowth of harmful bacteria linked to the infection. It’s essential to complete the full course of treatment as prescribed to ensure the infection is fully treated and to lower the chances of recurrence.

Metronidazole helps restore the natural balance of bacteria in the vagina and relieve BV symptoms. Always consult with a healthcare provider to receive a proper diagnosis and treatment plan suited to your needs.

To purchase Metronidazole 400mg online, complete the online consultation form at courierpharmacy.co.uk.

What is the Active Ingredient in Metronidazole 400mg?

The active ingredient in Metronidazole 400mg is metronidazole.

To purchase Metronidazole 400mg online, complete the online consultation form at courierpharmacy.co.uk.

What is Metronidazole 400mg Used For?

Metronidazole 400mg is a widely prescribed treatment for bacterial vaginosis (BV), a condition caused by an imbalance in the natural bacteria of the vagina. BV is the most common vaginal infection among women of reproductive age, often triggered by an overgrowth of bacteria like Gardnerella vaginalis and other anaerobes. This imbalance can lead to symptoms such as unusual vaginal discharge, a strong fishy odor, itching, and discomfort.

Metronidazole can be purchased online if you've had BV before and it was successfully treated by your GP.

You may be eligible for online BV treatment if you:

  • Experience symptoms like a fishy odor and thin discharge
  • Have been diagnosed with BV by your doctor
  • Have had a positive result from a home test for BV
  • Have previously been prescribed Metronidazole for BV

If it’s your first time dealing with BV, if your symptoms don’t match typical BV signs, or if you've received a negative test result, it’s best to consult your GP or visit a sexual health clinic for further assessment.

For confirmation of BV, you can use a Canestest Home Kit. Vaginal discharge and odor may also be caused by other infections, including STIs, so identifying the cause is important for choosing the right treatment.

Treating Recurrent BV with Metronidazole

Metronidazole tablets can be used to treat recurring BV. In some cases, BV may come back within three months after initial treatment. If Metronidazole worked for you before and your symptoms return, you can safely use it again.

However, if you experience BV more than twice in six months or four times in a year, seek advice from your GP or a sexual health clinic.

To order Metronidazole 400mg online, complete the online consultation form at courierpharmacy.co.uk.

How Does Metronidazole 400mg Work?

Metronidazole 400mg is an effective treatment for bacterial vaginosis (BV), working as an antibiotic to target and eliminate harmful bacteria. Here’s how it works:

  • Targeted Action on Bacteria: Metronidazole is specifically effective against the anaerobic bacteria often found in BV. These bacteria thrive in low-oxygen environments, and Metronidazole disrupts their DNA, stopping them from multiplying and causing their destruction.

  • Restoring Normal Vaginal Flora: BV causes an imbalance in the vaginal flora, where good bacteria like lactobacilli decrease, and harmful bacteria grow. By eliminating the harmful bacteria, Metronidazole helps bring back the natural balance of bacteria in the vagina.

  • Reducing BV Symptoms: As it eliminates the harmful bacteria, Metronidazole helps reduce the common symptoms of BV, such as unusual discharge and a fishy odor.

  • Effective in Vaginal Tissues: When taken orally, Metronidazole is well absorbed into the body and reaches the vaginal tissues where it works effectively to combat the infection.

By restoring the right balance of bacteria in the vagina, Metronidazole helps clear up the symptoms of BV and supports a healthy microbial environment.

You can purchase Metronidazole 400mg online at courierpharmacy.co.uk after completing the online consultation form.

How to Take Metronidazole 400mg

  • Take one tablet twice a day for 7 days, ideally with or after meals.
  • Finish the full course of treatment, even if your symptoms improve, to ensure the infection is fully treated.
  • Do not drink alcohol during the treatment and for at least 48 hours after completing the course. Alcohol can cause side effects such as nausea and vomiting when combined with Metronidazole.

You can buy Metronidazole 400mg online from courierpharmacy.co.uk after completing the online consultation form.

Who Should Not Take Metronidazole 400mg?

Do not take Metronidazole tablets if you:

  • Are allergic to Metronidazole or any of its ingredients. Signs of an allergic reaction include a rash, difficulty breathing or swallowing, or swelling of the lips, face, throat, or tongue. Please refer to the patient information leaflet for more details.

If you have any of the following conditions, avoid taking Metronidazole. If you're unsure, consult your doctor or pharmacist before starting the medication.

Warnings and Precautions
Consult your doctor or pharmacist before using Metronidazole if you:

  • Have liver problems
  • Are undergoing kidney dialysis
  • Have a nervous system disorder

If you have a history of Cockayne syndrome, your doctor should monitor your liver function closely during and after treatment with Metronidazole.

If you experience any of these symptoms, stop taking Metronidazole and contact your doctor immediately:

  • Abdominal pain
  • Loss of appetite
  • Nausea and vomiting
  • Fever
  • Fatigue or general malaise
  • Jaundice (yellowing of skin or eyes)
  • Dark urine
  • Clay-colored stools
  • Itching

Food and Drink
Avoid alcohol during your treatment and for 48 hours after finishing Metronidazole. Drinking alcohol may cause unpleasant reactions such as nausea, vomiting, stomach pain, hot flushes, rapid heartbeat, and headaches.

Pregnancy and Breastfeeding
If you're pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Metronidazole. It should only be used during pregnancy if necessary and may not be suitable for breastfeeding due to potential transfer into breast milk.

Driving and Using Machines
Metronidazole can cause side effects like dizziness, confusion, or visual disturbances. If you experience these effects, avoid driving or operating machinery.

Monitoring
If you are taking Metronidazole for more than 10 days, your doctor may recommend additional tests to monitor your health.

You can purchase Metronidazole 400mg online from courierpharmacy.co.uk after completing the online consultation form.

What Are the Side Effects of Metronidazole 400mg?

Metronidazole, like all medications, can cause side effects, although not everyone will experience them.

Seek immediate medical help if you notice:

  • Swelling in the hands, feet, ankles, face, lips, or throat, which may cause difficulty swallowing or breathing. You may also develop an itchy rash or hives. These could be signs of an allergic reaction to Metronidazole.
  • Skin rashes that involve blistering, peeling, or bleeding around the lips, eyes, mouth, nose, or genitals, along with flu-like symptoms and a high fever. This could indicate Stevens-Johnson Syndrome or toxic epidermal necrolysis.
  • Rare but serious side effects such as encephalopathy, which can present with fever, a stiff neck, headache, hallucinations, difficulty moving arms or legs, trouble speaking, or confusion.

Contact your doctor right away if you notice:

  • Unexplained infections, mouth ulcers, bruising, bleeding gums, or extreme tiredness, which may signal a blood problem.
  • Yellowing of the skin and eyes, a potential sign of liver issues (jaundice).
  • Severe abdominal pain that may extend to your back, which could indicate pancreatitis.

Let your doctor or pharmacist know if you experience:

  • Rare side effects (affecting fewer than 1 in 10,000 people) like confusion, hallucinations, seizures, drowsiness, dizziness, blurred or double vision, headaches, severe liver problems, dark urine, or muscle and joint pain.
  • Side effects of unknown frequency, such as nausea, vomiting, upset stomach, diarrhea, depression, numbness, tingling, limb weakness, an unpleasant taste, coated tongue, loss of appetite, fever, eye pain (optic neuritis), or symptoms that include fever, nausea, vomiting, headache, a stiff neck, and light sensitivity, which may indicate meningitis.
  • Hearing loss, tinnitus (ringing in the ears), or recurring rashes or skin discoloration.

Reporting Side Effects
If you experience any side effects, speak with your doctor, pharmacist, or nurse. You can also report side effects via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or by searching for MHRA Yellow Card in the Google Play or Apple App Store. Reporting helps improve the understanding of this medication’s safety.

You can purchase Metronidazole 400mg online from courierpharmacy.co.uk after completing the online consultation form.

Does Metronidazole 400mg Interact with Other Medicines?

It is important to inform your doctor or pharmacist if you are currently taking, or have recently taken, any other medications, including over-the-counter and herbal remedies. Metronidazole may interact with certain drugs, which can affect how they work or cause side effects. Be particularly cautious with the following:

Potential drug interactions include:

  • Anticoagulants like warfarin, which may need dosage adjustments
  • Lithium, which could impact kidney function
  • Antiepileptic medications such as phenytoin, primidone, and phenobarbitone
  • 5-fluorouracil, used for cancer treatment
  • Busulfan, used for leukemia
  • Ciclosporin, used for organ transplants
  • Disulfiram, used for treating alcoholism

For your safety, always consult your doctor or pharmacist if you're taking any of these medications before starting Metronidazole. You can purchase Metronidazole 400mg online from courierpharmacy.co.uk after completing the online consultation form.

Metronidazole 400mg FAQs

What Causes Bacterial Vaginosis?

Bacterial Vaginosis (BV) occurs when the balance of normal bacteria in the vagina is disrupted. Normally, the vagina contains a mix of bacteria, but BV happens when certain harmful bacteria, like Gardnerella vaginalis, grow out of control. Factors that may increase the risk of BV include:

  • Having multiple or new sexual partners
  • Douching or using scented vaginal products
  • Smoking
  • Hormonal changes or imbalances

While BV is not classified as a sexually transmitted infection (STI), sexual activity can increase the risk of developing it.

How Does Metronidazole Work?

Metronidazole works by targeting and eliminating the harmful bacteria that cause bacterial vaginosis (BV). It is an antibiotic that specifically combats anaerobic bacteria, which thrive in low-oxygen environments. By reducing the number of these bacteria, Metronidazole helps restore the natural bacterial balance in the vagina, relieving symptoms like unusual discharge and odor.

Can I Drink Alcohol with Metronidazole?

No, you should avoid drinking alcohol while taking Metronidazole and for at least 48 hours after completing your treatment. Drinking alcohol with Metronidazole can cause a reaction known as disulfiram-like syndrome, which can lead to severe nausea, vomiting, stomach pain, hot flashes, and a rapid heartbeat.

Can I Buy Metronidazole Online?

Yes, you can purchase Metronidazole online if you have been diagnosed with bacterial vaginosis by a healthcare provider. To qualify for online treatment, you should:

  • Have experienced symptoms like a fishy odor and thin discharge
  • Have a prior diagnosis of BV
  • Have tested positive for BV at home or previously used Metronidazole

If you're unsure about your symptoms or haven't been diagnosed with BV before, it's best to consult your GP or a sexual health clinic for further advice.

Can Metronidazole Be Used to Treat Thrush?

No, Metronidazole is not effective for treating thrush, a yeast infection caused by fungal overgrowth. Thrush typically causes a cottage cheese-like discharge and lacks the fishy odor found with BV. Thrush is best treated with antifungal medications.

What Are the Alternatives to Metronidazole for Treating BV?

Besides Metronidazole, other treatment options include:

  • Zidoval: A vaginal gel with Metronidazole, used daily for 5 days.
  • Balance Activ BV Gel: A non-prescription gel that helps restore vaginal pH and supports normal bacterial growth, often used alongside Metronidazole.

How Should I Take Metronidazole for BV?

Take one Metronidazole tablet twice a day for 7 days, ideally with or after meals. Finish the full course to ensure the infection is completely treated and to prevent it from coming back. Avoid alcohol during treatment and for 48 hours after completing the course.

How Can BV Be Prevented?

To reduce the risk of BV, consider the following:

  • Use condoms with multiple sexual partners
  • Avoid scented products around the vagina
  • Always wipe from front to back after using the toilet
  • Wear breathable underwear
  • Consider adding probiotics to your diet

These measures can help prevent BV from recurring.

What Side Effects Can Metronidazole Cause?

Metronidazole may cause some side effects, including:

  • Rare but serious reactions like allergic responses, severe skin conditions (e.g., Stevens-Johnson Syndrome), and encephalopathy.
  • Less common effects such as nausea, vomiting, headaches, dizziness, or changes in vision.
  • Other rare effects like tingling in limbs, changes in taste, stomach upset, or mood changes.

If you experience severe side effects, seek medical advice immediately.

Can Metronidazole Be Taken with Other Medications?

Be sure to inform your doctor or pharmacist if you are taking any other medications, especially:

  • Anticoagulants (e.g., warfarin)
  • Lithium
  • Epilepsy medications (e.g., phenytoin)
  • Cancer treatments (e.g., 5-fluorouracil)
  • Disulfiram (for alcoholism)

Can I Drink Alcohol While Taking Metronidazole?

No, you should avoid alcohol during your treatment with Metronidazole and for 48 hours after completing it. Drinking alcohol can cause unpleasant reactions like nausea, vomiting, and stomach pain.

Does Metronidazole Affect Contraception?

No, Metronidazole does not interfere with hormonal contraceptives.

Can Metronidazole Be Used During Pregnancy?

Metronidazole may sometimes be prescribed during pregnancy for vaginal infections. While there is no strong evidence that it harms the baby, consult your doctor before using Metronidazole during pregnancy to ensure it's safe for you.

For more information or to purchase Metronidazole 400mg online, visit courierpharmacy.co.uk after completing the online consultation form.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.11952.pdf

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Checked By
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Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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