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Differin 0.1% Gel

from£29.99

What Is Differin?

Differin is a prescription-only topical treatment designed to clear acne and improve skin texture. It contains adapalene, a retinoid (a form of vitamin A) that helps reduce inflammation and speed up skin cell turnover.

How Does Differin Work?

  • Prevents new acne breakouts by stopping pores from becoming clogged.
  • Clears existing acne, including blackheads, whiteheads, and pimples.
  • Reduces inflammation, helping to calm red and swollen spots.
  • Improves overall skin texture, making the skin smoother and more even.

Who Can Use Differin?

  • Suitable for adults and adolescents aged 12 years and older.
  • Typically applied once daily to affected areas.

Why Is Differin a Popular Acne Treatment?

  • Effective yet gentle, making it suitable for long-term acne management.
  • Helps control breakouts without excessive dryness or irritation.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

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Acne

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Cream

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In stock

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Differin 0.1% Gel
SKU: DIFCGEL Category: Tags: ,

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Quantity

1 x 45g, 2 x 45g, 3 x 45g

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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What Is Differin?

Differin is a topical acne treatment that contains adapalene, a retinoid derived from vitamin A. It works by increasing skin cell turnover, preventing clogged pores, and reducing inflammation, which helps to clear acne and prevent new breakouts.

How Does Differin Work?

  • Promotes faster skin renewal, helping to remove dead skin cells.
  • Unclogs pores, preventing the buildup of oil and bacteria.
  • Reduces inflammation, calming red and irritated breakouts.
  • Prevents future acne, making it effective for long-term use.

Who Can Use Differin?

  • Suitable for adults and adolescents aged 12 years and older.
  • Applied once daily to the affected areas.

What Forms of Differin Are Available?

  • Gel – Lightweight and fast-absorbing.
  • Cream – Suitable for dry or sensitive skin.

Why Is Differin Recommended for Acne?

  • Helps clear existing acne and prevents new breakouts.
  • Supports long-term skin health by improving texture and reducing scarring.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

What Is the Active Ingredient in Differin?

Differin contains adapalene 0.1%, a retinoid (vitamin A derivative) that helps treat acne by regulating skin cell turnover, preventing clogged pores, and reducing inflammation.

How Does Adapalene Work?

  • Prevents clogged pores by reducing excess skin cell buildup.
  • Fights acne-causing inflammation, helping to calm breakouts.
  • Encourages natural exfoliation, promoting smoother, clearer skin.
  • Reduces blackheads, whiteheads, and pimples, improving overall skin texture.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

What Is Differin Used For?

Differin is a topical acne treatment designed to help clear breakouts and improve skin texture. It is effective in managing mild to moderate acne, including blackheads, whiteheads, and inflamed pimples that commonly appear on the face, chest, and back.

How Does Differin Help Treat Acne?

  • Unclogs pores, preventing the buildup of oil and dead skin cells.
  • Reduces inflammation, calming red and irritated breakouts.
  • Encourages skin cell renewal, helping to shed dead skin and prevent clogged pores.
  • Treats existing acne and prevents new blemishes, promoting clearer skin over time.

Who Can Use Differin?

  • Suitable for adults and adolescents aged 12 years and older.
  • Commonly used for long-term acne management.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

How Does Differin Work?

Differin contains adapalene, a retinoid (vitamin A derivative) that targets the underlying causes of acne. It works by regulating skin cell turnover, reducing inflammation, and preventing new breakouts.

How Does Differin Help with Acne?

  • Regulates Skin Cell Turnover

    • Prevents dead skin cells from clogging pores, reducing blackheads and whiteheads.
    • Helps keep pores clear, preventing breakouts before they start.
  • Reduces Inflammation

    • Contains anti-inflammatory properties that calm redness and swelling.
    • Treats existing acne while reducing the risk of new pimples forming.
  • Prevents New Acne Breakouts

    • By keeping pores clear and reducing irritation, Differin helps stop acne from returning.
    • Supports smoother, healthier-looking skin over time.

What Are the Benefits of Differin?

  • Improves skin texture, making it feel smoother and more even.
  • Reduces the frequency of breakouts, promoting clearer skin.
  • Long-term acne management, making it ideal for consistent use.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

How Do You Use Differin?

Always follow your doctor's instructions when using Differin. If you are unsure about how to apply it, consult a doctor or pharmacist for guidance.

Who Can Use Differin?

  • Suitable for adults and adolescents aged 12 years and over.
  • For external use only – do not ingest or apply to broken skin.

How to Apply Differin

  • Use Differin once daily, preferably at night before bed, unless your doctor advises otherwise.
  • Cleanse the affected area with water and pat the skin dry before application.
  • Apply a thin layer to the affected areas using your fingertips and gently rub it in.
  • Wash your hands after application to prevent unintentional transfer to sensitive areas.

How Long Should You Use Differin?

  • Treatment duration depends on how quickly your acne improves.
  • After 3 months, consult your doctor to assess progress and decide whether to continue use.

What If You Use Too Much Differin or Accidentally Swallow It?

  • Applying excess Differin will not speed up acne clearance but may cause redness, irritation, peeling, or discomfort.
  • If accidentally swallowed, seek medical attention immediately.

What If You Miss a Dose?

  • If you forget to apply Differin, use it as soon as you remember.
  • Do not apply extra to make up for a missed dose—simply continue with your regular schedule.

Need More Advice?

If you have any concerns about using Differin, speak to your doctor or pharmacist for guidance.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

Who Should Not Use Differin?

Differin is an effective acne treatment, but it may not be suitable for everyone. If you have any concerns about using this medication, consult a doctor or pharmacist before starting treatment.

Do Not Use Differin If:

  • You are pregnant or planning to become pregnant – Differin should not be used during pregnancy.
  • You have allergies to adapalene or any other ingredients – Refer to the patient information leaflet for a full list of ingredients.

Warnings and Precautions

Skin Conditions

  • Do not apply Differin to skin with cuts, scrapes, sunburn, or eczema, as this may cause irritation.

Sensitive Areas

  • Avoid contact with the eyes, mouth, corners of the nose, and other sensitive areas.
  • If accidental contact occurs, rinse immediately with warm water.

Sunlight and UV Exposure

  • Limit exposure to strong sunlight and artificial UV light while using Differin.
  • Always use sunscreen and protective clothing on treated areas to reduce the risk of sun damage.

Skin Irritation

  • If you experience redness, sensitivity, or irritation, stop using Differin and consult a doctor.
  • Your doctor may advise reducing application frequency or taking a break from treatment until your skin recovers.

Pregnancy, Breastfeeding, and Fertility

Pregnancy

  • Do not use Differin if you are pregnant or planning to conceive.
  • If you become pregnant while using Differin, stop treatment immediately and speak to your doctor.

Breastfeeding

  • Differin can be used while breastfeeding, but avoid applying it to the chest area to prevent accidental exposure to the baby.

Ingredients to Be Aware Of

  • Methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate (E216) – These may cause allergic reactions, which can sometimes be delayed.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

What Are the Side Effects of Differin?

Like all medications, Differin Cream may cause side effects, though not everyone will experience them. Most side effects occur at the application site and are usually mild.

When to Seek Immediate Medical Attention

If you experience any of the following symptoms, stop using Differin and seek urgent medical help, as these could indicate a serious allergic reaction (angioedema):

  • Swelling of the face, lips, or throat, which may cause difficulty swallowing or breathing
  • Rash, itching, or hives
  • Dizziness

These reactions are rare, and their exact frequency is unknown.

Common Side Effects (Affect up to 1 in 10 People)

  • Dry skin
  • Skin irritation
  • Burning sensation at the application site
  • Redness (erythema)

Uncommon Side Effects (Affect up to 1 in 100 People)

  • Contact dermatitis (local skin reaction)
  • Skin discomfort
  • Sunburn
  • Itchy skin (pruritus)
  • Peeling skin (exfoliation)
  • Temporary acne flare-ups

Rare Side Effects (Frequency Not Known)

  • Allergic skin reaction
  • Pain or swelling of the skin
  • Irritation, redness, itching, or swelling of the eyelids
  • Darkening of lighter skin tones
  • Lightening of darker skin tones
  • Burn at the application site, ranging from mild to, in rare cases, severe burns

Reporting Side Effects

  • If you experience any side effects, including those not listed here, speak to a doctor or pharmacist.
  • You can also report side effects through the MHRA Yellow Card Scheme:
  • Reporting side effects helps improve medicine safety information.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

Does Differin Interact with Other Medicines?

Before using Differin, inform your doctor or pharmacist if you are taking, have recently taken, or plan to take any other medications. While Differin is generally safe for use with certain acne treatments and cosmetics, there are a few important guidelines to follow.

Can Differin Be Used with Other Acne Treatments?

  • Benzoyl peroxide, erythromycin, or clindamycin can be used alongside Differin, but they should be applied in the morning, while Differin should be applied at night.
  • Using both treatments at the same time may cause excessive dryness or irritation, so it’s important to space out applications.

Can You Use Makeup and Skincare Products with Differin?

  • Yes, cosmetics can be used, but they should be non-comedogenic (won’t clog pores) and oil-free.
  • Avoid products that over-dry the skin, as Differin can already cause mild dryness or irritation.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

Differin FAQs

What Is Differin Gel/Cream?

Differin Gel and Cream are prescription-only acne treatments applied directly to the skin. They are ideal for individuals who prefer not to take oral antibiotics. The active ingredient, adapalene, is a retinoid (vitamin A derivative) that helps reduce inflammation and improve skin texture by targeting blackheads, whiteheads, and pustules.

Differin is available in 45g tubes and is typically used once daily for at least three months to treat mild to moderate acne.

How Does Differin Work?

  • Regulates skin cell turnover, preventing pores from becoming clogged.
  • Reduces excess keratin production, which helps prevent breakouts.
  • Unclogs sebaceous glands, allowing oil (sebum) to flow naturally.
  • Minimizes inflammation, helping to calm existing breakouts.
  • Encourages exfoliation, keeping pores clear and reducing the formation of acne.

How Should I Use Differin?

  • Who Can Use It?
    • Suitable for adults and adolescents aged 12 and over.
  • How to Apply:
    • Apply a thin layer to affected areas once daily, preferably at night.
    • Ensure the skin is clean and dry before application.
    • Gently rub it in, and wash your hands afterward.
  • Duration of Use:
    • Use continuously for at least three months for best results.
    • Improvements may be noticeable within a few weeks, but full benefits are seen with consistent use.

What Are the Side Effects of Differin?

Common Side Effects:

  • Dry skin
  • Skin irritation
  • Burning sensation
  • Redness

Uncommon Side Effects:

  • Contact dermatitis (skin reaction from irritants or allergens)
  • Skin discomfort
  • Sunburn
  • Peeling skin
  • Temporary acne flare-up

Rare Side Effects (Seek Medical Help Immediately):

  • Swelling of the face, lips, or throat, which may cause difficulty swallowing or breathing.
  • Severe allergic reactions, such as rash or itching.

Always read the Patient Information Leaflet for a full list of side effects. If you experience any severe or unusual symptoms, consult a doctor or pharmacist.

What Precautions Should I Take While Using Differin?

  • Avoid Applying to Damaged Skin: Do not use on cuts, scrapes, sunburn, or areas with eczema.
  • Sensitive Areas: Keep away from eyes, mouth, and nostrils. If contact occurs, rinse thoroughly with warm water.
  • Sun Exposure:
    • Avoid strong sunlight and UV light (such as tanning beds).
    • Use sunscreen and protective clothing to protect treated skin.
  • Other Acne Treatments:
    • Inform your doctor or pharmacist if you use other acne products.
    • If using benzoyl peroxide, erythromycin, or clindamycin, apply them in the morning and Differin at night to prevent excessive irritation.

Can I Use Differin During Pregnancy or Breastfeeding?

  • Do not use Differin if you are pregnant or planning to conceive.
  • If you become pregnant while using Differin, stop treatment immediately and inform your doctor.
  • Breastfeeding:
    • Differin can be used while breastfeeding, but avoid applying it to the chest area to prevent contact with the baby.
    • Always consult your doctor or pharmacist before using any acne treatment during pregnancy or breastfeeding.

Where to Buy Differin Online?

Differin is available for purchase from Courier Pharmacy after completing an online consultation to confirm suitability.

Visit courierpharmacy.co.uk to place your order and receive fast, discreet delivery straight to your door.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.921.pdf

No profile picture available.
Checked By
No author selected.
No qualification available.
No user selected.
Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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