Quviviq is a prescription medication for adults struggling with insomnia, whether it’s difficulty falling asleep or staying asleep.
How does Quviviq work?
Quviviq blocks orexin, a brain chemical responsible for wakefulness. By reducing orexin activity, it helps promote natural sleep without heavy sedation.
How do you take Quviviq?
Quviviq is taken as a tablet once per night, ideally 30 minutes before bedtime. It is designed to improve sleep quality without causing grogginess the next morning.
How is Quviviq different from other sleep aids?
Unlike traditional sleeping pills that sedate the brain, Quviviq helps regulate the sleep-wake cycle, making it a safer option with a lower risk of dependency.
Where can I buy Quviviq?
Quviviq is available online at courierpharmacy.co.uk. Simply complete an online consultation to check if it’s suitable for you.
Quviviq is a prescription medication designed to help adults with insomnia who struggle to fall asleep or stay asleep.
How does Quviviq work?
Quviviq works by blocking orexin, a brain chemical responsible for keeping you awake. By reducing wakefulness, it helps you fall asleep faster and stay asleep longer.
How do you take Quviviq?
Quviviq is taken as a tablet, usually once per night before bed. It helps improve sleep without causing next-day drowsiness, making it a suitable option for those needing a restful night without feeling groggy the next morning.
How is Quviviq different from traditional sleep aids?
Unlike some sleeping pills that sedate the brain, Quviviq targets the sleep-wake cycle, allowing for a more natural sleep pattern with a lower risk of dependence.
Where can I buy Quviviq?
Quviviq is available online at courierpharmacy.co.uk. To purchase, complete a quick online consultation to ensure it is the right treatment for you.
Additional information
Pack size
30 tablets
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Quviviq 25mg Overview
Quviviq 25mg tablets contain daridorexant, a medication specifically developed to help adults struggling with insomnia, whether they have trouble falling asleep or staying asleep. Unlike traditional sleep aids, Quviviq works by reducing wakefulness, allowing for a more natural sleep cycle without significantly altering sleep patterns.
Key Features
Active Ingredient: Daridorexant 25mg
How It Works: Quviviq is a dual orexin receptor antagonist (DORA), which blocks orexin, a brain chemical responsible for promoting wakefulness.
Benefits: Helps with both sleep onset (falling asleep) and sleep maintenance (staying asleep), supporting a more restful sleep without the grogginess often associated with other sleeping pills.
Dosage and Use: Take once daily, about 30 minutes before bed, ensuring you have at least seven hours of sleep time.
Safety and Tolerance: Compared to traditional sleep medications, Quviviq has a lower risk of dependence and tolerance. It is also designed to reduce side effects such as daytime drowsiness.
To purchase Quviviq 25mg tablets, complete a short online consultation at courierpharmacy.co.uk.
Active Ingredients in Quviviq 25mg
Each Quviviq 25mg tablet contains daridorexant hydrochloride, which is equivalent to 25mg of daridorexant. This active ingredient works by blocking orexin, a brain chemical responsible for wakefulness, helping individuals with insomnia fall asleep faster and stay asleep longer.
What is Quviviq 25mg Used For?
Quviviq 25mg (daridorexant) is prescribed for adults experiencing chronic insomnia, where difficulty falling asleep or staying asleep has lasted for at least three months and significantly impacts daily activities.
The National Institute for Health and Care Excellence (NICE) recommends daridorexant for adults who experience insomnia at least three nights a week for three months or longer, especially when it affects daytime functioning.
It is typically advised for individuals who have already tried cognitive behavioural therapy for insomnia (CBTi) but found it ineffective, unavailable, or unsuitable.
Quviviq should be used short-term, with a review after three months to assess its effectiveness. If there is no improvement, treatment should be discontinued. If continued, regular evaluations are necessary to ensure it remains beneficial.
How Does Quviviq Work?
Quviviq (daridorexant) is designed to help people with insomnia by reducing wakefulness and making it easier to fall asleep and stay asleep.
It works as a dual orexin receptor antagonist (DORA), meaning it blocks the effects of orexin, a brain chemical that keeps you awake and alert. Normally, orexin neuropeptides (orexin A and orexin B) activate receptors in the brain to promote wakefulness. Daridorexant blocks both orexin 1 and orexin 2 receptors, reducing the urge to stay awake and helping the body transition into sleep naturally.
Unlike some traditional sleep medications, Quviviq does not alter the natural sleep cycle. Research in both humans and animals has shown that it allows the body to go through the usual sleep stages, ensuring a restful and restorative sleep experience without disrupting normal sleep patterns. This makes Quviviq a modern alternative for managing insomnia while maintaining natural sleep structure.
How to Take Quviviq 25mg
The standard recommended dose of Quviviq (daridorexant) is 50mg once daily, taken about 30 minutes before bedtime.
For some individuals, such as those with moderate liver issues, a lower dose of 25mg may be more appropriate. This dose should also be taken once a day, around 30 minutes before sleep.
Always follow your doctor’s instructions on the correct dosage for your specific needs.
Who Should Not Take Quviviq 25mg Tablets?
Quviviq is not suitable for individuals who:
Have narcolepsy.
Have severe liver disease (severe hepatic impairment).
Use Quviviq with caution if you:
Have a history of depression or other mental health conditions, as it may worsen symptoms, including suicidal thoughts.
Have obstructive sleep apnea (OSA) or chronic obstructive pulmonary disease (COPD).
Are over 75 years old, as there is limited data on its safety and effectiveness in this age group. While studies haven't shown an increased risk of falls, older adults are generally more prone to them.
Have a history of alcohol or drug abuse, as there may be a risk of dependence.
Plan to drive, operate heavy machinery, or perform tasks requiring full alertness, especially in the first few days of treatment. Use caution until you know how Quviviq affects you.
Consume alcohol, as combining it with Quviviq can impair coordination and alertness.
Central Nervous System (CNS) Effects
Since Quviviq reduces wakefulness, avoid driving, operating heavy machinery, or engaging in risky activities until you feel fully alert. When taken alongside other CNS depressants or alcohol, it can have stronger sedative effects, and dose adjustments may be required.
Pregnancy and Breastfeeding
Avoid using Quviviq during pregnancy or while breastfeeding unless absolutely necessary. There is limited safety data, so consult your doctor before use.
What Are the Side Effects of Quviviq 25mg Tablets?
Sleep-Related Issues
Some people may experience sleep paralysis, hallucinations, or cataplexy-like symptoms, particularly in the first few weeks of treatment. If these symptoms occur, speak to a healthcare professional to assess whether the medication should be adjusted or discontinued.
Common Side Effects
The most frequently reported side effects of daridorexant include:
Headaches
Drowsiness
Dizziness
Fatigue
Nausea
These effects are generally mild to moderate and do not seem to worsen with higher doses. Older adults tend to experience the same side effects as younger individuals.
Uncommon Side Effects
Hypersensitivity reactions (rash or hives)
Hallucinations
Nightmares or unusual dreams
Sleepwalking
Rare Side Effects
Sleep paralysis and hallucinations (especially within the first few weeks of treatment)
Increased drowsiness during the day
In clinical studies, drowsiness was reported in 3% of patients taking 25mg and 2% of those taking 50mg, compared to 2% in those taking a placebo.
When to Seek Medical Advice
If you experience any severe side effects or unexpected symptoms while taking Quviviq 25mg, consult a healthcare professional immediately.
Reporting Side Effects
To help monitor the safety of this medication, report any suspected side effects to the Yellow Card Scheme, available online or through mobile apps.
Does Quviviq Interact with Other Medicines?
Enzyme Blockers (CYP3A4 Inhibitors)
CYP3A4 is an enzyme that helps break down many medications in the body. Taking Quviviq (daridorexant 25mg) with drugs that block this enzyme can increase its levels in your system.
Examples of CYP3A4 inhibitors:
Diltiazem (for high blood pressure)
Erythromycin, Ciprofloxacin (antibiotics)
Cyclosporine (used after organ transplants)
If you are taking any of these medications, the recommended dose of daridorexant may need to be adjusted to 25mg.
Strong CYP3A4 inhibitors to avoid:
Itraconazole (for fungal infections)
Ritonavir (for HIV)
Grapefruit (avoid in the evening, as it can increase Quviviq levels)
Enzyme Boosters (CYP3A4 Inducers)
Some medications speed up the breakdown of daridorexant, making it less effective.
Examples of CYP3A4 inducers:
Efavirenz (for HIV)
If you are taking an enzyme inducer, Quviviq may not work as well because it is broken down too quickly.
Stomach Acid Reducers (Gastric pH Modifiers)
Some heartburn or acid reflux medications can affect how Quviviq is absorbed.
Example:Famotidine (used for heartburn)
These medications may lower peak daridorexant levels, but the total amount in your body remains the same. No dose change is needed.
How Daridorexant Affects Other Drugs
CYP3A4-Dependent Medications
Some drugs rely on CYP3A4 for processing. Quviviq can slightly increase their levels.
Examples:
Midazolam (sedative)
Simvastatin (cholesterol-lowering medication – use caution with high doses)
Tacrolimus (used after organ transplants)
Birth control pills are not affected by Quviviq, so they remain safe to use.
CYP2C9-Dependent Medications
CYP2C9 is another enzyme responsible for processing certain drugs.
Example:Warfarin (a blood thinner)
Quviviq does not interfere with this enzyme, so no dose adjustment is required.
Transport Proteins (BCRP or P-gp)
These proteins help transport drugs in and out of cells.
Quviviq does not affect BCRP-dependent drugs like rosuvastatin (for cholesterol).
It can slightly increase levels of P-gp-dependent drugs, such as dabigatran (a blood thinner), so extra caution is needed.
Alcohol and Quviviq
Drinking alcohol with Quviviq does not change the total amount of the drug in your body.
However, it can delay absorption and increase drowsiness, affecting your ability to stay alert.
If you consume alcohol while taking Quviviq, avoid driving or using heavy machinery due to the increased risk of reduced alertness.
Final Advice
Before starting Quviviq 25mg, inform your doctor or pharmacist about any medications you are taking to ensure there are no potential interactions.
Quviviq FAQs
What is Quviviq?
Quviviq is a prescription medication designed to help people with insomnia. It aids sleep by making it easier to fall asleep and stay asleep throughout the night.
How does Quviviq work?
Quviviq works by blocking the effects of orexin, a brain chemical that regulates wakefulness. By reducing wakefulness signals, it helps promote sleep.
How should I take Quviviq?
Take Quviviq exactly as prescribed by your doctor.
Usually taken as one tablet before bedtime.
Only take it when you have at least 7 to 8 hours to sleep.
Can I take Quviviq with other medications?
Inform your doctor about any other medications, including over-the-counter or herbal treatments, as some may interact with Quviviq.
What happens if I miss a dose?
If you forget to take Quviviq, do not double the next dose.
Skip the missed dose and take your next dose as scheduled.
Are there any side effects?
Some people may experience:
Drowsiness
Dizziness
Headaches
If you notice unusual or severe side effects, speak with your doctor.
Can I drink alcohol while taking Quviviq?
Avoid alcohol while using Quviviq, as it can increase drowsiness and other side effects.
Is Quviviq safe during pregnancy or breastfeeding?
There is limited information on Quviviq's safety during pregnancy.
If you are breastfeeding, consult your doctor as the drug may pass into breast milk.
How long can I take Quviviq?
The duration of treatment depends on your individual condition.
It is usually prescribed for short-term use, but your doctor will advise how long you should take it.
What should I do if Quviviq doesn’t work for me?
If Quviviq does not improve your sleep after a few days, speak to your doctor. They may adjust your dose or explore alternative treatments.
Where can I buy Quviviq?
You can order Quviviq online from courierpharmacy.co.uk after completing a quick online consultation form.
