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Low Dose Naltrexone 1.5mg capsules
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Low Dose Naltrexone 1.5mg Capsules
Low Dose Naltrexone (LDN) 3mg capsules are a lower-dose version of naltrexone, a medication typically used to treat opioid and alcohol dependence. In smaller doses, LDN is believed to help regulate the immune system and reduce inflammation, making it a popular off-label treatment for certain chronic conditions.
What is Low Dose Naltrexone 1.5mg used for?
LDN 1.5mg is commonly prescribed off-label and is thougtht to help manage symptoms of:
Autoimmune diseases, including multiple sclerosis (MS), lupus, and rheumatoid arthritis
Chronic pain conditions, such as fibromyalgia and complex regional pain syndrome
Inflammatory bowel diseases, like Crohn’s disease and ulcerative colitis
Other conditions involving chronic inflammation or immune system imbalances such as Long COVID
How does Low Dose Naltrexone work?
LDN blocks opioid receptors temporarily, encouraging the body to increase endorphin production. Endorphins help regulate immune function and reduce inflammation, which may improve symptoms of pain, fatigue, and immune-related conditions.
How do you take Low Dose Naltrexone 1.5mg?
The usual dose that is taken once daily, typically taken before bedtime is called the maintenance dose, and for some this may be 1.5mg.
Doses may vary depending on the condition being treated. Some patients may start at a lower dose and gradually increase under medical supervision.
Always follow your doctor’s guidance for the correct dosage.
What are the possible side effects of Low Dose Naltrexone?
Most people tolerate LDN well, but some may experience mild side effects, including:
Sleep disturbances, such as vivid dreams or trouble sleeping
Digestive discomfort, including nausea or an upset stomach
Mild headaches
These effects often subside as the body adjusts to the medication. If symptoms persist, consult a healthcare professional.
Who should not take Low Dose Naltrexone?
LDN is not suitable for individuals who are currently taking opioid medications, as it may block their effects and trigger withdrawal symptoms. You should also:
Inform your doctor about any medications or supplements you are taking to avoid interactions.
Consult a healthcare professional if you are pregnant or breastfeeding before using LDN.
How should Low Dose Naltrexone 1.5mg be stored?
Keep capsules in a cool, dry place, away from direct sunlight and moisture.
Store out of reach of children.
Do I need a consultation before taking Low Dose Naltrexone?
Yes. LDN is a prescription medication, and a consultation with a healthcare provider is required to determine if it is appropriate for your condition.
You can purchase Low Dose Naltrexone 1.5mg Capsules from courierpharmacy.co.uk after completing an online consultation.
Low Dose Naltrexone 1.5mg Capsules – Product Information
What is Low Dose Naltrexone (LDN) 1.5mg?
Low Dose Naltrexone (LDN) 1.5mg capsules are a specially compounded are a lower-dose formulation of naltrexone, a medication originally designed for treating opioid and alcohol dependence.
Although it is used for opioid and alcohol addiction in doses of 50mg, when the dose is reduced to around 4.5mg and lower, LDN is believed to help regulate the immune system and reduce inflammation in smaller doses.
What is Low Dose Naltrexone 1.5mg used for?
LDN 1.5mg is commonly prescribed and beleived to help manage symptoms of:
Autoimmune diseases: Including multiple sclerosis (MS), lupus, and rheumatoid arthritis.
Chronic pain conditions: Such as fibromyalgia and complex regional pain syndrome (CRPS).
Inflammatory bowel diseases: Including Crohn’s disease and ulcerative colitis.
Other conditions: Involving chronic inflammation or immune system imbalances.
How does Low Dose Naltrexone work?
LDN works by temporarily blocking opioid receptors, which encourages the body to increase its production of endorphins. Endorphins are natural chemicals that help:
Regulate immune function.
Reduce inflammation.
Improve symptoms of pain, fatigue, and immune-related conditions.
How do you take Low Dose Naltrexone 1.5mg?
The typical dose is 1.5mg once daily, usually taken before bedtime.
For some conditions, patients may start at a lower dose and gradually increase under medical supervision.
Always follow your doctor’s instructions regarding dosage.
What are the possible side effects of Low Dose Naltrexone?
Most people tolerate LDN well, but mild side effects can occur, including:
Sleep disturbances: Such as vivid dreams or trouble sleeping.
Digestive discomfort: Including nausea or an upset stomach.
Mild headaches.
These side effects often subside as your body adjusts to the medication. If symptoms persist, consult a healthcare professional.
Who should not take Low Dose Naltrexone?
LDN is not suitable for everyone. Avoid taking LDN if:
You are currently taking opioid medications, as it may block their effects and cause withdrawal symptoms.
You are pregnant or breastfeeding, unless advised by a healthcare professional.
Always inform your doctor about any medications or supplements you are taking to avoid potential interactions.
How should Low Dose Naltrexone 1.5mg be stored?
Store capsules in a cool, dry place, away from direct sunlight and moisture.
Keep out of reach of children.
Do I need a consultation before taking Low Dose Naltrexone?
Yes, LDN is a prescription-only medication, and you must consult with a healthcare provider to determine if it is suitable for your condition.
At Courier Pharmacy, you can purchase Low Dose Naltrexone 1.5mg Capsules after completing a simple online consultation with one of our healthcare professionals. With all purchases of LDN from Courier Pharmacy you are entitled to free follow up consultations with one of our specialist prescribers.
Begin your LDN consultation today
Ready to explore the benefits of Low Dose Naltrexone 1.5mg? Visit courierpharmacy.co.uk to start your online consultation and take the first step toward managing your condition safely and effectively.
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What are Low Dose Naltrexone (LDN) 1.5mg capsules?
Low Dose Naltrexone (LDN) 1.5mg capsules are a specially compounded, low-dose formulation of naltrexone, a medication traditionally prescribed in 50mg doses to treat opioid and alcohol addiction. Unlike the standard dose, LDN is tailored to deliver much smaller amounts, typically between 1mg and 4.5mg, for alternative therapeutic applications such as managing chronic pain, fibromyalgia, and autoimmune conditions.
Why Choose LDN 1.5mg capsules?
This specific 1.5mg dose has been compounded to meet the needs of patients requiring a lower starting dose for their treatment. If your required dose is not listed, we can compound a custom dose to suit your needs.
LDN: A tale of two doses
At higher doses (50mg), naltrexone fully blocks opioid receptors to prevent the effects of opioids.
At lower doses (around 1mg to 4.5mg), LDN partially blocks these receptors, encouraging the body to produce more opioid receptors and endorphins. This process helps regulate the immune system and reduce inflammation, making LDN effective for conditions like fibromyalgia, multiple sclerosis, Crohn’s disease, and other autoimmune or chronic pain disorders.
LDN 1.5mg capsules are commonly used off-label for their immune-modulating and anti-inflammatory benefits, offering relief for a variety of chronic health conditions.
What is the active ingredient in Low Dose Naltrexone (LDN) 1.5mg capsules?
The active ingredient in Low Dose Naltrexone (LDN) 1.5mg capsules is naltrexone hydrochloride, precisely formulated at a dose of 1.5mg.
What are Low Dose Naltrexone (LDN) 1.5mg capsules used for?
Low Dose Naltrexone (LDN) 1.5mg capsules are often prescribed off-label to help manage a variety of chronic and inflammatory conditions. Common uses include:
Autoimmune conditions
LDN is believed to regulate the immune system and reduce inflammation, making it a potential treatment for autoimmune diseases such as:
Multiple sclerosis (MS)
Rheumatoid arthritis
Lupus
Hashimoto’s thyroiditis
Chronic Pain Conditions
LDN may assist with pain relief and inflammation in long-term pain disorders, including:
Fibromyalgia
Complex regional pain syndrome (CRPS)
Digestive & inflammatory bowel disorders
LDN has shown promise in reducing gut inflammation and managing symptoms of conditions such as:
Crohn’s disease
Ulcerative colitis
Irritable bowel syndrome (IBS)
Cancer support
Some patients use LDN alongside conventional cancer treatments, as it may help boost the immune system. However, further research is required to confirm its effectiveness in this area.
Neurological conditions
LDN is being explored for its potential benefits in conditions affecting the brain and nervous system, such as:
Parkinson’s disease
Alzheimer’s disease
Since LDN is not yet widely approved for these uses, it is essential to consult a healthcare provider to determine if it is appropriate for your specific condition and health needs.
How do Low Dose Naltrexone (LDN) 1.5mg capsules work?
Low Dose Naltrexone (LDN) 1.5mg capsules work differently from the standard 50mg dose used for opioid addiction. While higher doses fully block opioid receptors, LDN in smaller doses (0.1mg to 4.5mg) partially blocks these receptors, triggering unique effects in the body.
Boosting natural painkillers
At low doses, LDN partially blocks opioid receptors, prompting the body to compensate by increasing its production of endorphins—your natural painkillers. This boost in endorphins helps manage chronic pain and supports immune regulation, making it particularly beneficial for autoimmune conditions and inflammation-related disorders.
Regulating the immune system
LDN also interacts with Toll-Like Receptors (TLRs), specifically TLR4, which are proteins that play a key role in the immune system. When TLRs become overactive, they can lead to excessive inflammation, contributing to chronic pain and autoimmune diseases.
Levo-Naltrexone: The "left-handed" form of naltrexone partially blocks opioid receptors, stimulating endorphin production and reducing pain.
Dextro-Naltrexone: The "right-handed" form targets TLR4 receptors, calming overactive immune responses and reducing inflammation.
By modulating these systems, LDN helps to balance the immune system and reduce chronic inflammation.
How LDN helps
Boosts Endorphins: Encourages the body to produce more natural painkillers, alleviating chronic pain and improving immune function.
Reduces Inflammation: Blocks TLR4 receptors in immune cells like microglia, helping to calm excessive inflammation that contributes to pain and autoimmune conditions.
Supports Immune Balance: Helps regulate an overactive immune system, making it a promising option for autoimmune diseases, chronic pain disorders, and other inflammatory conditions.
Summary
LDN 1.5mg capsules provide a dual-action approach: they boost natural endorphin production to manage pain and partially block TLR4 receptors to reduce inflammation. This combination makes LDN an innovative therapy for conditions like chronic pain, autoimmune disorders, and inflammation-related diseases. Always consult your healthcare provider to determine if LDN is suitable for your condition.
How to take Low Dose Naltrexone (LDN) 1.5mg capsules
LDN 1.5mg capsules can be used either as a step-up dose during gradual dose increases (titration) or as a long-term maintenance dose, depending on how effectively it relieves your symptoms and any side effects you experience.
Dosage guidelines for LDN 1.5mg capsules
Standard Dose: Take one 1.5mg capsule daily, preferably before bedtime. Nighttime dosing aligns with the body’s natural endorphin production cycle.
Consistency: Take the capsule at the same time every day to maintain steady levels of the medication in your system.
With or Without Food: LDN can be taken with or without food, but sticking to a consistent routine can help improve adherence.
How to Take: Swallow the capsule whole with a glass of water. Do not crush or chew the capsule.
Timing Adjustments: If taking LDN at night causes sleep disturbances, consult your doctor. They may recommend switching to a morning dose.
Always follow the specific instructions provided by your healthcare provider. They may adjust your dose or timing based on your condition and how your body responds to the medication.
Who should not use Low Dose Naltrexone (LDN)?
While Low Dose Naltrexone (LDN) is generally well-tolerated, there are specific situations where its use may not be appropriate. Below are key precautions to consider:
Opiate use and LDN
Avoid Using Opiates: Do not take LDN 1.5mg capsules if you are using opiates, as LDN can block their effects. Combining the two can result in serious breathing and circulation issues, increasing the risk of opiate poisoning.
Opiate Dependency: LDN should not be started if you are dependent on opiates, as it can cause severe withdrawal symptoms.
Emergency Surgery or Anaesthesia: Inform your healthcare provider that you are taking LDN if you require surgery or anaesthesia. Non-opiate anaesthetics are preferred. If opioids are necessary, higher doses may be required under strict medical supervision, as this increases the risk of breathing and circulation problems.
Risk of Overdose: Do not attempt to counteract LDN’s blocking effects by taking large amounts of opiates. Once LDN wears off, any remaining opiates in your system could lead to an accidental overdose, which can be life-threatening.
Liver and kidney health
LDN is processed by the liver and kidneys. If you have liver issues, your doctor may monitor your liver function before and during treatment to ensure it is safe for use.
Other medications and LDN
Always inform your doctor about any medications or over-the-counter drugs you are taking.
Medicines Containing Opiates: Certain medications, such as some cough syrups, painkillers, or diarrhoea treatments, may not work properly with LDN and should be avoided.
Emergency Pain Relief: If opioid-based pain relief is necessary, higher doses may be required under close medical supervision to manage risks such as breathing difficulties.
Pregnancy and breastfeeding with LDN
If you are pregnant, breastfeeding, or planning to become pregnant, consult your doctor before using LDN.
LDN should only be used during pregnancy if the potential benefits outweigh the risks to the baby.
Breastfeeding is not recommended while taking LDN, as it is unclear whether the medication passes into breast milk.
Driving and using machinery with LDN
LDN may cause drowsiness or reduced alertness in some individuals.
If you feel tired, dizzy, or unable to focus, avoid driving or operating heavy machinery.
Always follow your doctor’s guidance and discuss any concerns or questions about LDN use to ensure it is safe and suitable for your specific situation.
Low Dose Naltrexone (LDN) 1.5mg capsules: Possible side effects
LDN 1.5mg capsules are generally well-tolerated, but like any medication, they may cause side effects. These are typically mild and often improve as your body adjusts to the treatment.
Common side effects
Sleep Disturbances: Vivid dreams or occasional trouble sleeping, especially during the initial stages of treatment.
Digestive Issues: Mild nausea, constipation, or diarrhoea may occur as your body adapts.
Fatigue: Some individuals may feel unusually tired or drowsy.
Headaches: Mild to moderate headaches are sometimes reported.
Mood Shifts: Slight mood changes or occasional feelings of euphoria may occur.
Muscle and Joint Aches: Mild discomfort in muscles or joints has been noted in some cases.
These side effects are usually temporary and tend to subside as your body becomes accustomed to the medication. If any side effects persist or become bothersome, consult your doctor or pharmacist for further advice.
Do Low Dose Naltrexone (LDN) 1.5mg capsules interact with other medicines?
Before starting LDN, it’s important to inform your doctor or pharmacist about all medications you are currently taking, have recently taken, or plan to take, including over-the-counter products.
Opioid medications and LDN
LDN works by blocking opioid receptors, which can reduce the effectiveness of opioid-based medications.
Some common medications, such as certain cough syrups, diarrhoea treatments, or painkillers, may contain opioids. Always consult your doctor or pharmacist before using these products.
Emergency pain relief
If opioid-based painkillers are required in an emergency, higher doses may be needed to achieve effective pain relief.
This must be done under strict medical supervision to manage potential risks, such as breathing difficulties or prolonged side effects.
Always consult your doctor or pharmacist about your current medications to ensure that LDN is safe and suitable for you.
Low Dose Naltrexone (LDN) 1.5mg capsules FAQs
What is Low Dose Naltrexone (LDN)?
Low Dose Naltrexone (LDN) is a low-dose formulation of naltrexone, usually prescribed in doses between 0.5mg and 4.5mg. It is used off-label to help manage chronic pain, autoimmune conditions, and to support the immune system. LDN works by increasing the body’s natural production of endorphins (pain-relieving chemicals) and reducing inflammation.
How does LDN work?
LDN temporarily blocks opioid receptors, which stimulates the body to produce more endorphins. These endorphins help reduce pain and support immune balance. LDN also regulates inflammation, making it beneficial for conditions involving chronic inflammation or immune system dysfunction.
What conditions is LDN used for?
LDN is thought to help with the following conditions:
Chronic Pain Disorders: Fibromyalgia and complex regional pain syndrome (CRPS).
Inflammatory Bowel Diseases: Crohn’s disease and ulcerative colitis.
Neurological Conditions: Parkinson’s disease and Alzheimer’s disease.
Cancer Support Therapy: Sometimes used alongside traditional treatments.
How do I take LDN 1.5mg capsules?
Standard Dose: Take LDN once daily, preferably before bedtime.
Timing Adjustments: If it causes sleep disturbances, switch to a morning dose.
Consistency: Take it at the same time every day to maintain steady levels.
With or Without Food: LDN can be taken with or without food, depending on your preference.
What are the common side effects of LDN?
LDN is generally well-tolerated, but some people may experience:
Sleep Problems: Vivid dreams or difficulty sleeping.
Digestive Issues: Mild nausea, constipation, or diarrhoea.
Headaches: Usually mild and temporary.
Fatigue or Mood Changes: Temporary tiredness or emotional shifts.
These side effects typically improve as the body adjusts to the medication.
Can LDN be taken with other medications?
LDN is generally safe with most medications, but you should inform your doctor about all medicines you’re taking, especially:
Opioid-Based Painkillers: LDN can block their effects, reducing their effectiveness.
Immune-Modulating Drugs: LDN may interact with these, so medical supervision is essential.
Is LDN safe for long-term use?
Yes, LDN is considered safe for long-term use. Regular check-ups with your doctor are recommended to monitor your progress and manage any changes in symptoms or side effects.
Can I take LDN while pregnant or breastfeeding?
LDN should only be used during pregnancy or breastfeeding if recommended by your doctor. There is limited research on its safety in these situations, so always consult a healthcare provider first.
Will stopping LDN cause withdrawal symptoms?
Unlike higher doses of naltrexone used for addiction treatment, LDN does not typically cause withdrawal symptoms. However, it’s best to discontinue under medical guidance to ensure a smooth process.
How long does it take for LDN to work?
Some individuals notice improvements within a few days, while others may take weeks or months to experience the full benefits. The effects of LDN build over time, so patience is important.
Can LDN be used to treat Long COVID?
There is increasing interest in using LDN to manage symptoms of long COVID. Its ability to reduce inflammation and regulate the immune system makes it a potential option for addressing symptoms like fatigue, brain fog, and chronic pain. While research is ongoing, some individuals have reported positive results. For more information, see "Can LDN help with Long COVID?".
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