Ibuprofen 400mg Tablets (84)

Quantity	1 x 84 tablets, 2 x 84 tablets

What is Ibuprofen?

Ibuprofen is a type of NSAID (non-steroidal anti-inflammatory drug) that helps to relieve pain and reduce fever. It works by blocking natural substances in the body that cause inflammation. Ibuprofen is commonly used for short-term relief of mild to moderate pain. It is effective for treating conditions like headaches, including migraines, dental pain, menstrual cramps, and fever. This medicine is often selected for its fast and effective action in managing pain and reducing inflammation.

You can purchase Ibuprofen online from courierpharmacy.co.uk after completing an online consultation form.

What is the Active Ingredient in Ibuprofen 400mg Tablets?

Each film-coated tablet contains 400 mg of ibuprofen, which is the active ingredient responsible for relieving pain and reducing inflammation.

You can purchase Ibuprofen 400mg tablets online from courierpharmacy.co.uk after completing an online consultation form.

What is Ibuprofen Used For?

Ibuprofen tablets are commonly used to relieve mild to moderate pain, reduce inflammation and swelling, and lower fever.

Some of the common uses of Ibuprofen include:

Relieving headaches and migraines
Managing back pain
Treating arthritis pain
Alleviating toothache
Reducing fever
Easing symptoms of cold and flu
Relieving menstrual cramps
Soothing muscle and joint pain

You can order Ibuprofen online from courierpharmacy.co.uk after completing an online consultation form.

How Does Ibuprofen Work?

Ibuprofen works by blocking the action of an enzyme called cyclooxygenase (COX). COX plays a key role in producing prostaglandins, which are substances in the body that cause pain, inflammation, and fever.

When you have an injury or illness, your body makes more prostaglandins in the affected area, causing symptoms like swelling, pain, and fever. By inhibiting COX, ibuprofen reduces the production of prostaglandins, which helps relieve these symptoms.

Ibuprofen is non-selective, meaning it blocks both COX-1 and COX-2 enzymes. COX-1 helps protect the stomach lining and supports kidney function, while COX-2 is mainly involved in inflammation. By inhibiting COX-2, ibuprofen provides pain relief and reduces inflammation, but it may also cause some side effects like stomach irritation due to the inhibition of COX-1.

In short, ibuprofen works by lowering the levels of substances that cause pain, inflammation, and fever, giving you relief from these symptoms.

You can buy Ibuprofen online at courierpharmacy.co.uk after completing the online consultation form.

How to Take Ibuprofen

When taking Ibuprofen, follow your doctor's instructions exactly. If you are unsure about the directions, ask your doctor or pharmacist. To minimize side effects, use the lowest effective dose for the shortest time possible.

Ibuprofen is intended for short-term use. The correct dosage depends on your age and weight. Recommended doses are as follows:

For Mild to Moderate Pain and Fever:

Adults and children over 12 (weighing 40kg or more):
- 200 mg tablets: Take 1-2 tablets as a single dose or up to 3-4 times a day with a 6-hour gap. Do not exceed 6 tablets (1200 mg) in 24 hours.
- 400 mg tablets: Take ½ to 1 tablet as a single dose or up to 3-4 times a day with a 6-hour gap. Do not exceed 3 tablets (1200 mg) in 24 hours.

For Migraine Headaches:

Adults and children over 12 (weighing 40kg or more):
- 200 mg tablets: Take 2 tablets as a single dose. If needed, take 2 more tablets after 6 hours. Do not exceed 6 tablets (1200 mg) in 24 hours.
- 400 mg tablets: Take 1 tablet as a single dose. If needed, take 1 more tablet after 6 hours. Do not exceed 3 tablets (1200 mg) in 24 hours.

For Period Pain:

Adults and children over 12 (weighing 40kg or more):
- 200 mg tablets: Take 1-2 tablets 1-3 times a day with a 4-6 hour gap. Do not exceed 6 tablets (1200 mg) in 24 hours.
- 400 mg tablets: Take ½ to 1 tablet 1-3 times a day with a 4-6 hour gap. Do not exceed 3 tablets (1200 mg) in 24 hours.

How to Take Ibuprofen:

Swallow tablets with a glass of water, preferably with or after food. If you have a sensitive stomach, take Ibuprofen during meals.
Tablets can be split to make swallowing easier or to adjust the dosage.

Important Notes:

If you are an adult and your condition does not improve within 3 days for migraines or fever, or within 4 days for pain or period pain, consult your doctor.
For children or adolescents, do not use Ibuprofen for more than 3 days without consulting a doctor.
Elderly patients should consult their doctor before taking Ibuprofen due to potential risks, such as digestive issues.
If you have reduced kidney or liver function, speak to your doctor before taking Ibuprofen.

In Case of Overdose:

If you or a child accidentally take more Ibuprofen than recommended, seek immediate medical help. Symptoms of an overdose include nausea, stomach pain, vomiting, diarrhea, and more severe issues like dizziness, chest pain, or trouble breathing. Call your local hospital for immediate guidance.

What to Do If You Miss a Dose:

Do not take a double dose. Just continue with your regular schedule.

For further questions, speak with your doctor or pharmacist.

You can buy Ibuprofen online at courierpharmacy.co.uk after completing the online consultation form.

Who Should Not Take Ibuprofen?

You should avoid taking Ibuprofen if:

You are allergic to ibuprofen or any of its ingredients (see section 6 for details).
You have had allergic reactions, such as asthma, a runny nose, itchy skin rashes, or swelling of the lips, face, tongue, or throat after using aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs).
You have experienced gastrointestinal bleeding or perforation linked to NSAID use.
You have stomach or intestinal ulcers or bleeding (especially if you've had two or more episodes).
You have severe liver, kidney, or heart problems.
You are in the last three months of pregnancy.
You are severely dehydrated due to vomiting, diarrhea, or insufficient fluid intake.
You have active bleeding, including in the brain.
You have a blood cell disorder of unknown origin.

Children under 12 years old should not use Ibuprofen.

Warnings and Precautions

Consult your doctor before using Ibuprofen if:

You have Systemic Lupus Erythematosus (SLE) or mixed connective tissue diseases.
You have a genetic blood disorder called porphyria.
You suffer from chronic inflammatory bowel diseases like ulcerative colitis, Crohn’s disease, or other digestive issues.
You have blood cell formation disorders or problems with normal blood clotting.
You suffer from allergies, hay fever, asthma, chronic sinus problems, or other respiratory issues, as these conditions may increase the risk of breathing difficulties.
You have liver, kidney, or heart problems.
You have recently had major surgery.
You are in the first six months of pregnancy or are breastfeeding.
You are using Ibuprofen for more than the recommended duration or higher doses than advised, as this can cause serious side effects, including stomach, gut, kidney issues, or dangerously low potassium levels.

Allergic Reactions:

Signs of an allergic reaction to Ibuprofen include trouble breathing, swelling of the face or neck (angioedema), or chest pain. If you experience these symptoms, stop taking Ibuprofen and seek immediate medical help.

Infections:

Ibuprofen can mask symptoms of infections, such as pain and fever, potentially delaying treatment and increasing the risk of complications. This is especially important for bacterial pneumonia or infections linked to chickenpox. If your infection worsens or persists, contact your doctor.

Elderly Patients:

Older adults may be at higher risk for side effects like digestive tract bleeding, which can be life-threatening.

Stomach and Intestinal Issues:

If you’ve had a stomach or intestinal ulcer, particularly one complicated by bleeding, be cautious when using Ibuprofen. Report any unusual abdominal symptoms to your doctor. If bleeding or ulceration occurs, discontinue treatment immediately.

Skin Reactions:

Ibuprofen may cause serious skin reactions, including rashes, blisters, or other allergic symptoms. If you notice these symptoms, stop taking the medication and seek medical help right away.

Avoid using Ibuprofen during chickenpox (varicella) due to the increased risk of serious skin reactions.

Heart and Brain Effects:

NSAIDs like Ibuprofen can slightly increase the risk of heart attack or stroke, especially with high doses. Do not exceed the recommended dose or duration of treatment. Consult your doctor if you have heart problems, high blood pressure, diabetes, high cholesterol, or a family history of heart disease or stroke, or if you are a smoker.

Kidney Effects:

Ibuprofen can lead to kidney damage, particularly in individuals with existing kidney, heart, or liver issues, or those taking diuretics or ACE inhibitors. Stopping Ibuprofen usually results in recovery.

Aseptic Meningitis:

Inflammation of the brain's protective membranes, called aseptic meningitis, has been reported in some patients, especially those with autoimmune conditions like SLE. Symptoms include neck stiffness, headache, nausea, vomiting, fever, or confusion.

Other Precautions:

Severe Allergic Reactions: Rarely, Ibuprofen can cause severe reactions like anaphylactic shock. If you experience any of these, stop taking Ibuprofen and seek immediate medical assistance.
Medication Overuse Headaches: Taking painkillers regularly for headaches can worsen them. If you experience frequent or daily headaches despite treatment, consult your doctor.
Kidney Damage: Habitual use of painkillers can lead to permanent kidney damage.
Infections: Ibuprofen may mask symptoms of infection, such as fever or pain, and prolong bleeding time. It may also reduce fertility, so consult your doctor if you’re trying to conceive.

Use in Children and Adolescents:

Ibuprofen is not recommended for children under 12 years old and may cause kidney issues in dehydrated adolescents.

Serious Skin Reactions:

If you develop severe skin reactions such as blisters or peeling skin, stop using Ibuprofen and seek medical help immediately.

Alcohol:

Avoid alcohol while taking Ibuprofen, as it can increase the risk of side effects, particularly affecting the stomach, intestines, or central nervous system.

Pregnancy, Breastfeeding, and Fertility:

Do not take Ibuprofen in the last three months of pregnancy as it could harm your baby. Use during the first six months of pregnancy should only occur under medical advice. Ibuprofen appears in breast milk in small amounts, but long-term use may require early weaning.

Driving and Using Machines:

While Ibuprofen doesn’t typically affect your ability to drive, high doses can cause fatigue, drowsiness, dizziness, or visual problems, which can impair your ability to drive safely. Alcohol can worsen these effects.

Sodium Content:

Ibuprofen contains less than 1 mmol (23 mg) of sodium per 200 mg or 400 mg tablet, so it is essentially sodium-free.

Kidney Issues:

Ibuprofen may cause kidney problems even in people without prior kidney issues, leading to swelling in the legs, heart failure, or high blood pressure. Stopping Ibuprofen usually results in recovery.

For more information and to purchase Ibuprofen online, visit courierpharmacy.co.uk after completing an online consultation.

What are the side effects of Ibuprofen?

Like all medications, ibuprofen can cause side effects. Not everyone will experience them, and the likelihood of side effects depends on the dosage and the individual. Below is an overview of potential side effects, but keep in mind that you should always follow the guidance of a healthcare professional.

Common Side Effects

These side effects affect more than 1 in 10 people and typically relate to the digestive system. They can include:

Nausea
Vomiting
Diarrhea
Constipation
Flatulence (wind)
Indigestion
Abdominal pain

In some cases, more serious side effects, such as gastrointestinal ulcers, bleeding, or perforation, can occur. This can be particularly dangerous for older adults.

Less Common Side Effects

These side effects may affect up to 1 in 100 people:

Heartburn
Abdominal pain
Stomach ulcers, with or without bleeding
Bowel inflammation or worsening of existing conditions like Crohn’s disease
Mouth ulcers or inflammation (ulcerative stomatitis)
Difficulty breathing (bronchospasm)
Headaches, dizziness, or fatigue
Skin rash or itching

Serious Side Effects

In rare cases, you might experience more severe side effects. These should be taken seriously and reported to a doctor immediately:

Severe allergic reactions, such as swelling of the face, tongue, or throat, which could cause difficulty breathing (angioedema)
Chest pain, which might indicate a heart attack or severe allergic reaction
Severe skin reactions like blistering or peeling, particularly around the mouth, eyes, or genital area
Sudden weight gain due to fluid retention
Kidney damage, which may lead to issues with fluid and electrolyte balance
Liver issues, including yellowing of the skin or eyes (jaundice)
Ringing in the ears (tinnitus)

Rare Side Effects

Very rare side effects include:

Swelling or fluid in the lungs, causing shortness of breath
Severe skin reactions like Stevens-Johnson syndrome or Lyell’s syndrome, which may cause severe blistering and sloughing off of the skin
Anemia or other blood disorders, such as low white blood cell count
Liver failure or inflammation of the pancreas
Sudden loss of vision or other visual disturbances

What to Do If You Experience Side Effects

If you experience any of the above, especially serious or severe symptoms, stop using ibuprofen and seek medical attention immediately.

Side Effects by Frequency

Very Common (may affect more than 1 in 10 people):
- Nausea, vomiting, diarrhea, constipation, indigestion
Common (may affect up to 1 in 10 people):
- Abdominal pain, heartburn, or digestive issues
Uncommon (may affect up to 1 in 100 people):
- Visual disturbances, hypersensitivity reactions like hives or asthma attacks
Rare (may affect up to 1 in 1,000 people):
- Depression, confusion, lupus-like symptoms, kidney tissue damage
Very Rare (may affect up to 1 in 10,000 people):
- Severe allergic reactions, heart failure, or severe skin reactions

Important Precautions

Infections: Ibuprofen can mask symptoms of infections, such as fever or pain, which may delay treatment. If your symptoms worsen or do not improve, consult your doctor.
Allergic Reactions: If you experience signs of an allergic reaction, such as difficulty breathing, stop taking ibuprofen immediately and seek urgent medical help.
Kidney and Liver Function: Ibuprofen can cause kidney damage, especially in people with existing kidney or heart problems. Always monitor your health and consult with your doctor if you're concerned.

If you are interested in purchasing ibuprofen or other medications, you can easily do so online through CourierPharmacy after completing our online consultation form.

Reporting Side Effects

If you experience any side effects not listed here, or if you're concerned about any reaction to ibuprofen, you should contact your doctor or pharmacist. Additionally, you can report side effects directly through the national reporting system (Yellow Card Scheme). Visit the MHRA Yellow Card website or search for "MHRA Yellow Card" in the Google Play or Apple App Store to help improve the safety of medicines.

Does Ibuprofen interact with other medicines?

It’s important to inform your doctor or pharmacist if you are taking, have recently taken, or plan to take any other medications. Ibuprofen can interact with several drugs, which may affect how ibuprofen works or how other medicines function.

Common Interactions with Ibuprofen

Other NSAIDs (such as COX-2 inhibitors) – may increase the risk of gastrointestinal ulcers or bleeding.
Blood thinners (e.g., warfarin or heparin) – ibuprofen may intensify their effects.
Platelet inhibitors (e.g., ticlopidine, clopidogrel) – may increase the risk of bleeding.
Methotrexate (for cancer or autoimmune diseases) – ibuprofen may enhance its effects.
Digoxin (for heart conditions) – ibuprofen may boost its effects.
Phenytoin (for epilepsy) – ibuprofen may enhance its effects.
Lithium (for depression or mania) – ibuprofen may intensify its effects.
Diuretics (e.g., water tablets) – ibuprofen may reduce their effectiveness.
Potassium-sparing diuretics – may cause high potassium levels (hyperkalemia).
Blood pressure medications (e.g., ACE inhibitors, beta-blockers, or ARBs) – ibuprofen may interfere with their effects.
Cholestyramine (for high cholesterol) – may reduce the absorption of ibuprofen.
Aminoglycosides (antibiotics) – ibuprofen can reduce their elimination.
SSRIs (e.g., paroxetine, sertraline) – may increase the risk of gastrointestinal bleeding.
Ciclosporine and tacrolimus (immunosuppressants) – may raise the risk of kidney damage.
Zidovudine or ritonavir (HIV medications) – ibuprofen may interact with these drugs.
Mifepristone – ibuprofen can reduce its effectiveness.
Probenecid or sulfinpyrazone (for gout) – can delay ibuprofen elimination.
Quinolone antibiotics – may increase the risk of seizures.
Sulfonylureas (for diabetes) – ibuprofen can affect blood sugar levels.
Glucocorticoids (for inflammation) – may increase the risk of ulcers or bleeding.
Bisphosphonates (for osteoporosis or high blood calcium levels) – may increase the risk of gastrointestinal issues.
Oxpentifylline (for circulatory problems) – may interact with ibuprofen.
Baclofen (muscle relaxant) – ibuprofen may increase baclofen toxicity.
Ginkgo biloba (herbal supplement) – may increase bleeding risks when combined with ibuprofen.
Voriconazole and fluconazole (antifungal treatments) – these can increase ibuprofen’s effect, requiring possible dose adjustments.

Other Considerations

There may be additional medications that interact with ibuprofen. It is essential to consult your doctor or pharmacist before combining ibuprofen with any other drugs. If you're looking to buy ibuprofen or other medications online, visit CourierPharmacy after completing our online consultation form.

Ibuprofen FAQs

What is Ibuprofen?

Ibuprofen 400mg tablets are commonly used to treat mild to moderate pain and inflammation. It is suitable for adults and children over 12 years old. Ibuprofen can also help reduce fever, often caused by colds or flu.

What is Ibuprofen used for?

Ibuprofen is frequently used to relieve:

Headaches and migraines
Back pain
Arthritis pain
Toothache
Fever
Cold and flu symptoms
Period pain
Muscle and joint pain

How does Ibuprofen work?

Ibuprofen is a Non-Steroidal Anti-Inflammatory Drug (NSAID). It works by blocking the production of prostaglandins, which are chemicals in the body that cause pain and swelling when you are injured.

How long does Ibuprofen take to work?

You can usually feel relief from Ibuprofen within 20 to 30 minutes. Its effects typically last 4 to 6 hours.

How long can you take Ibuprofen?

Ibuprofen should not be taken continuously for more than 10 days. If your pain continues beyond this period, speak to a pharmacist or doctor for further advice.

Can you take Ibuprofen with Paracetamol?

Yes, you can take Ibuprofen and paracetamol together as they relieve pain in different ways. Alternating doses can help manage mild to moderate pain effectively.

Can you take Ibuprofen with Codeine?

Ibuprofen and codeine can be used together, as they work in different ways to relieve pain. Some combination medications, like Nurofen Plus, are available over-the-counter. However, do not use codeine for more than 3 days due to the risk of addiction. Consult a doctor if your pain persists.

Naproxen, Aspirin, and Ibuprofen

Naproxen, Aspirin, and Ibuprofen are all NSAIDs, so do not take more than one NSAID at the same time unless instructed by a doctor. Avoid combining Naproxen or Aspirin with Ibuprofen.

Is Ibuprofen safe?

When used as directed, Ibuprofen is generally safe. However, like any medication, it can cause side effects, and some people may be allergic to it or its ingredients.

Coronavirus and Ibuprofen

Ibuprofen can be used to treat symptoms of COVID-19, such as fever, muscle aches, headaches, and sore throat. There is no strong evidence suggesting that Ibuprofen worsens COVID-19 symptoms.

How to take Ibuprofen

Always read the Patient Information Leaflet before using Ibuprofen. It should be taken orally, preferably with food or milk to avoid stomach irritation. Ibuprofen 400mg tablets are suitable for those over 12 years of age.

Ibuprofen Dose – How Much to Take?

For adults and children over 12 years old: Take one 400mg tablet up to three times a day. Do not exceed three tablets in 24 hours, allowing at least 4 hours between doses.

Ibuprofen Dose for Children

Children under 12 should take smaller doses, such as 200mg tablets or liquid suspension. Do not crush or chew the 400mg tablets.

What happens if you overdose on Ibuprofen?

Taking more than the recommended dose can be harmful. If you suspect an overdose, seek medical help immediately, even if you feel fine. Symptoms of overdose include stomach pain, nausea, drowsiness, ringing in the ears, trouble breathing, and an irregular heart rate.

Ibuprofen Side Effects

Like any medication, Ibuprofen can cause side effects. Common side effects include:

Headaches
Nausea
Vomiting
Indigestion
Constipation
Diarrhea
Skin rashes or hives

Most side effects go away once you stop the medication. Seek immediate medical attention if you experience severe side effects or an allergic reaction.

Ibuprofen Warnings

Always read the warnings and precautions in the Patient Information Leaflet before using Ibuprofen. Do not use Ibuprofen if you have a history of stomach ulcers or liver, kidney, or heart problems. Consult a doctor if you have asthma, diabetes, high blood pressure, high cholesterol, gastrointestinal disorders, or if you are taking other medications.

Can you take Ibuprofen on an empty stomach?

Avoid taking Ibuprofen on an empty stomach, as it may irritate your stomach. Always take it with food or a snack.

Ibuprofen and Pregnancy

Ibuprofen is not recommended during pregnancy. Talk to a healthcare professional for advice on managing pain during pregnancy. Ibuprofen can be used while breastfeeding at the recommended dose.

Can you drive while taking Ibuprofen?

Ibuprofen can cause drowsiness in some people. Make sure you know how it affects you before driving or operating machinery.

Ibuprofen and Alcohol

Drinking alcohol while taking Ibuprofen can increase the risk of stomach irritation. However, moderate alcohol consumption is generally considered safe when taking Ibuprofen.

For more information or to purchase Ibuprofen online, visit CourierPharmacy after completing your online consultation form.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.10952.pdf

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