Low Dose Naltrexone (LDN) 2mg capsules are a specially prepared, low-dose version of naltrexone, an opioid receptor antagonist. Unlike the standard 50mg dose used for treating opioid and alcohol dependency, LDN is administered in much smaller doses to help balance the immune system and address symptoms linked to various chronic conditions.
Uses:
Low Dose Naltrexone 2mg capsules are thought to help with the following:
Autoimmune diseases: Such as multiple sclerosis, lupus, and rheumatoid arthritis.
Chronic pain disorders: Including fibromyalgia and complex regional pain syndrome (CRPS).
Inflammatory bowel diseases: Like Crohn’s disease and ulcerative colitis.
Cancer support: Used alongside traditional cancer therapies to boost immune function.
Other conditions: Chronic inflammation or disorders related to immune dysfunction.
How it works:
LDN temporarily blocks opioid receptors in the body. This partial blockade is thought to stimulate the production of endorphins—your body’s natural pain relievers—and regulate immune system activity. This mechanism may help reduce inflammation, relieve pain, and restore immune balance.
Dosage:
The standard dosage for Low Dose Naltrexone 2mg capsules is one capsule taken daily, typically at bedtime. Taking it at night aligns with the body’s natural cycles and may enhance endorphin production. However, the dosage may vary based on the condition being treated and individual response. Always adhere to your healthcare provider’s guidance.
Side effects:
Common side effects of LDN 2mg capsules are generally mild and include:
Sleep disturbances, such as vivid dreams or occasional insomnia.
Gastrointestinal discomfort, including nausea or an upset stomach.
Mild headaches.
These effects are usually short-lived and tend to improve as your body adjusts to the medication. If side effects persist or worsen, consult your healthcare provider.
Precautions:
LDN should not be used by individuals currently taking opioid medications, as it may block their effects.
Inform your healthcare provider about all other medications or supplements you are taking to avoid interactions.
Pregnant or breastfeeding women should seek medical advice before starting LDN.
Storage:
Store LDN 2mg capsules in a cool, dry location, away from direct sunlight and moisture. Ensure they are kept out of reach of children.
Consultation:
Always consult with a healthcare provider before starting or adjusting Low Dose Naltrexone 2mg capsules. This ensures the treatment is tailored to your specific health needs and condition.
Additional information
Quantity
1 x 30, 2 x 30, 3 x 30, 4 x 30, 5 x 30, 6 x 30
MOJO WISDOM
Take control of your health by understanding your condition and what this medication is doing for you.
READ:
More information about this treatment.
UK-based doctors and pharmacists
Discreet and Confidential
UK-based doctors and pharmacists
Free, Expert Advice
No video link provided.
No video link provided.
UK-based doctors and pharmacists
Free, expert advice
Discrete and confidential
Fast delivery
Giving you trusted clinical advice for over 30 conditions
A UK regulated pharmacy providing safe, effective treatments online since 2014
Low Dose Naltrexone (LDN) 2mg capsules are a specially compounded, low-dose version of naltrexone. While standard naltrexone tablets are typically available in 50mg strengths and used to treat opioid and alcohol dependence, LDN is formulated in much smaller doses (1mg to 4.5mg) to provide therapeutic benefits for other conditions.
Higher doses of naltrexone (50mg) block the effects of opioids in addiction treatment. In contrast, lower doses are believed to help regulate the immune system and reduce inflammation, making LDN a promising option for managing autoimmune diseases, chronic pain, and inflammatory disorders.
LDN 2mg capsules are often used off-label as they may help with conditions such as multiple sclerosis, fibromyalgia, Crohn’s disease, and rheumatoid arthritis. By modulating the immune response and reducing inflammation, LDN may help improve symptom control and enhance quality of life.
Typically taken once daily, often at bedtime, LDN is not FDA-approved for these conditions, meaning its use is considered off-label. Always consult your healthcare provider to determine if LDN 2mg capsules are appropriate for your individual health needs. This means that you need to complete the Courier Pharmacy consultation before your can select and purchase your LDN.
What is the active ingredient in Low Dose Naltrexone (LDN) 2mg capsules?
The active ingredient in Low Dose Naltrexone 2mg capsules is naltrexone hydrochloride,compounded to contain a 2mg dose.
What are Low Dose Naltrexone (LDN) 2mg capsules used for?
Low Dose Naltrexone (LDN) 2mg capsules are commonly used off-label to help with a variety of chronic and inflammatory conditions. Here are some of the most frequent uses that LDN 2mg capsules may help with:
Autoimmune Diseases: LDN is often prescribed to manage conditions like multiple sclerosis (MS), rheumatoid arthritis, lupus, and Hashimoto’s thyroiditis. It helps regulate the immune system and reduce inflammation.
Chronic Pain Disorders: LDN may improve quality of life by reducing pain in conditions such as fibromyalgia and complex regional pain syndrome (CRPS).
Inflammatory Bowel Diseases: LDN has shown promise in easing symptoms of Crohn’s disease and ulcerative colitis by reducing gut inflammation.
Cancer Support: Some patients use LDN as a complementary therapy alongside traditional cancer treatments to boost the immune system and potentially improve outcomes, though more research is needed in this area.
Neurological Disorders: LDN has been explored for conditions like Parkinson’s disease and Alzheimer’s disease, where it may help slow progression and improve symptoms, although evidence is still developing.
Irritable Bowel Syndrome (IBS): LDN can help reduce intestinal inflammation, alleviating symptoms such as abdominal pain and irregular bowel movements.
While LDN 2mg capsules are generally well-tolerated, it is essential to consult a healthcare provider to ensure this treatment is appropriate for your specific condition and health needs.
How do Low Dose Naltrexone (LDN) 2mg capsules work?
Low Dose Naltrexone (LDN) 2mg capsules function differently from the standard 50mg dose used for opioid addiction treatment. While the higher dose fully blocks opioid receptors to prevent the effects of opioids, LDN at lower doses (typically 0.1mg to 6mg) only partially blocks these receptors. This partial blockade stimulates the body to produce more endorphins, which are natural painkillers, and also helps regulate the immune system.
How LDN works
1. Endorphin boost
By partially blocking opioid receptors, LDN encourages the production of endorphins. These natural chemicals play a critical role in relieving pain and balancing the immune system. This is particularly beneficial for conditions where the immune response is overactive or misregulated, such as autoimmune diseases and chronic inflammation.
2. Immune system regulation
The increase in endorphins helps modulate the immune system, reducing excessive inflammation and improving immune function. This makes LDN a helpful option for managing autoimmune diseases, chronic inflammatory conditions, and even some cancers. Endorphins also regulate cell growth, which may help slow the progression of certain diseases.
Role of Toll-Like Receptors (TLRs)
TLRs and inflammation
Toll-like receptors (TLRs) are proteins that trigger the immune system’s initial response to threats like bacteria and viruses. When over-activated, TLRs can lead to excessive inflammation, contributing to chronic pain and autoimmune conditions.
LDN and TLR4
LDN, particularly its "dextro" form, blocks TLR4, a specific toll-like receptor associated with harmful inflammation. By calming this overactive immune response, LDN helps reduce inflammation and alleviate symptoms of chronic pain and inflammatory disorders.
Additional Benefits
Chiral Nature of Naltrexone
Naltrexone exists in two forms: levo-naltrexone and dextro-naltrexone.
Levo-naltrexone: Partially blocks opioid receptors, boosting endorphin production and improving immune balance.
Dextro-naltrexone: Blocks TLR4, reducing inflammation and potentially aiding in cancer treatment.
Pain Relief and Inflammation Control
The dual action of LDN—boosting endorphins and calming inflammation through TLR4—makes it an effective option for managing pain, controlling inflammation, and supporting overall immune health.
Summary
Low Dose Naltrexone (LDN) 2mg capsules may offer a unique and innovative approach to managing pain and regulating the immune system. By increasing endorphin production and reducing harmful inflammation through TLR4, LDN provides potential benefits for a wide range of conditions, including chronic pain, autoimmune diseases, and inflammatory disorders. Always consult a healthcare provider to determine if LDN is suitable for your specific needs.
How to use Low Dose Naltrexone (LDN) 2mg capsules
To use Low Dose Naltrexone (LDN) 2mg capsules effectively, follow these general steps:
Dosage: Take one 2mg capsule daily, ideally at bedtime. Nighttime dosing aligns with your body’s natural rhythms and may boost endorphin production.
Consistency: Aim to take the capsule at the same time every day to maintain steady levels of the medication in your system.
With or without food: LDN capsules can be taken with or without food. Sticking to a routine can help improve adherence.
Swallowing: Swallow the capsule whole with a glass of water. Do not crush or chew the capsule.
Adjust timing if needed: If taking LDN at night causes sleep disturbances, consult your healthcare provider. They may suggest switching to a morning dose.
Always follow the specific instructions given by your healthcare provider. Your dosage or timing may be adjusted based on your individual health needs or condition. For more information about doses and dose titration, please contact us.
Who should not use Low Dose Naltrexone (LDN) 2mg capsules?
While Low Dose Naltrexone (LDN) 2mg capsules are generally well-tolerated, there are specific situations where their use may not be appropriate. Here are the key precautions to keep in mind:
Avoid opiates while using LDN
Do not take opiates alongside LDN 2mg capsules. LDN partially blocks the effects of opiates (such as the euphoric “high”), but combining the two can cause severe breathing difficulties, circulatory issues, or even opiate poisoning.
Dependency on opiates
LDN should not be used if you are currently dependent on opiates, as it can trigger severe withdrawal symptoms.
Anesthesia precautions
If you require anesthesia during an emergency, inform healthcare providers that you are taking LDN. Non-opiate-based anesthetics are preferred. If opiate-based anesthetics are necessary, higher doses may be required, increasing the risk of side effects like breathing difficulties and circulatory problems.
Risk of overdose
Avoid attempting to overcome LDN’s blocking effects by taking high doses of opiates. Even after LDN wears off, residual opiates in your system could lead to accidental overdose with serious consequences.
Liver and kidney health
As LDN is metabolized by the liver and kidneys, individuals with liver conditions should use it cautiously. Your doctor may perform liver function tests before and during treatment to ensure safety.
Other medications
Always inform your doctor about any medications, supplements, or over-the-counter drugs you are taking. Certain products, like cough syrups, diarrhea treatments, or pain relievers, may contain opiates and could interact with LDN. If opioid-based drugs are required in emergencies, higher doses may be necessary under close medical supervision to manage side effects like respiratory depression.
Pregnancy and breastfeeding
If you are pregnant, breastfeeding, planning to become pregnant, or think you might be pregnant, consult your doctor before using LDN 2mg capsules. LDN should only be used during pregnancy if the potential benefits outweigh the risks to the baby. Breastfeeding is generally not advised while taking LDN.
Driving and operating machinery
LDN may cause drowsiness or reduced alertness in some individuals. If you experience these effects, avoid driving or operating heavy machinery until you feel fully alert and capable.
Always consult your healthcare provider to determine if LDN 2mg capsules are suitable for your specific health needs and circumstances.
What are the side effects of Low Dose Naltrexone (LDN) 2mg capsules?
The side effects of Low Dose Naltrexone (LDN) 2mg capsules are usually mild and short-lived. However, some individuals may experience the following:
Sleep disturbances: Vivid dreams or occasional insomnia, particularly during the early stages of treatment.
Digestive issues: Nausea, constipation, or diarrhea may occur as your body adjusts to the medication.
Fatigue: Some users may feel unusually tired or drowsy.
Headaches: Mild to moderate headaches can develop in certain individuals.
Mood changes: Mood swings or feelings of euphoria are possible in rare cases.
Joint or muscle pain: Some people may experience mild discomfort or aches in muscles or joints.
These side effects are generally temporary and tend to improve as your body adapts to the medication. If any symptoms persist or worsen, it’s important to consult your healthcare provider for advice and possible adjustments to your treatment.
Does low dose naltrexone (LDN) 2mg capsules interact with other medicines?
It is important to inform your doctor if you are currently taking, have recently taken, or plan to take any other medications, including over-the-counter drugs or supplements. Certain medications, particularly those containing opiates, may not work effectively when combined with Low Dose Naltrexone (LDN) 2mg capsules.
Medications to watch for: Common medications such as cough syrups, diarrhea treatments, and pain relievers may contain opiates. If you require these, consult your doctor to ensure safe use.
Emergency situations: In cases where opioid-based drugs are necessary, higher doses may be required to achieve effective pain relief. This must be done under close medical supervision to manage the increased risk of respiratory depression and other prolonged or intensified side effects.
Always share your full list of medications with your healthcare provider before starting LDN 2mg capsules to avoid potential interactions and ensure safe treatment.
Low Dose Naltrexone (LDN) 2mg capsules FAQs
What is Low Dose Naltrexone (LDN)?
Low Dose Naltrexone (LDN) is a medication prescribed in small doses (typically 0.5mg to 4.5mg) to help manage various health conditions. It is often used for autoimmune diseases, chronic pain, and some neurological conditions. LDN works by boosting the body’s natural production of endorphins and regulating the immune system.
How does LDN work?
LDN temporarily blocks opioid receptors in the brain, which triggers the release of endorphins, your body’s natural painkillers. This helps reduce pain, control inflammation, and regulate immune responses, making it effective for conditions involving chronic inflammation or immune system dysfunction.
What conditions can LDN help treat?
LDN 2mg capsules may help with:
Fibromyalgia
Multiple sclerosis
Crohn’s disease
Rheumatoid arthritis
Lupus
Certain cancers
It is also used for chronic pain management and as a supportive treatment for immune-related disorders.
How do I take Low Dose Naltrexone (LDN) 2mg capsules?
LDN 2mg capsules are usually taken once daily, preferably at night before bedtime. If sleep disturbances occur, your doctor may suggest switching to a morning dose. Always follow your healthcare provider’s instructions for dosage and timing.
What are the common side effects of LDN?
Common side effects of LDN 2mg capsules include:
Sleep disturbances (e.g., vivid dreams or insomnia).
Nausea or digestive issues (e.g., constipation or diarrhea).
Headaches.
These side effects are generally temporary and often improve as your body adjusts to the medication.
Can LDN be taken with other medications?
LDN can usually be taken alongside other medications, but it’s crucial to inform your doctor about any medications or supplements you’re using. This helps prevent potential interactions, particularly with immune-modulating drugs or painkillers.
Is LDN safe for long-term use?
LDN is generally considered safe for long-term treatment. However, regular monitoring by your healthcare provider is important to address any side effects and ensure the treatment remains effective.
Can I take LDN if I’m pregnant or breastfeeding?
LDN should generally be avoided during pregnancy or breastfeeding unless specifically recommended by a healthcare provider. Due to limited research on its safety in these circumstances, consulting your doctor is essential.
Will LDN cause withdrawal symptoms?
Because LDN is used in much smaller doses compared to naltrexone for addiction treatment, it is unlikely to cause withdrawal symptoms. However, if you decide to stop taking LDN, consult your healthcare provider to ensure a safe and gradual discontinuation process.
How long does it take for LDN to work?
The time it takes for LDN to show results varies between individuals. Some people may feel improvements within a few days, while others may take several weeks to notice benefits. Patience is key, as the response time depends on the condition being treated and individual factors.
To provide the best experiences, we use technologies like cookies to store and/or access device information. Consenting to these technologies will allow us to process data such as browsing behavior or unique IDs on this site. Not consenting or withdrawing consent, may adversely affect certain features and functions.
Functional
Always active
The technical storage or access is strictly necessary for the legitimate purpose of enabling the use of a specific service explicitly requested by the subscriber or user, or for the sole purpose of carrying out the transmission of a communication over an electronic communications network.
Preferences
The technical storage or access is necessary for the legitimate purpose of storing preferences that are not requested by the subscriber or user.
Statistics
The technical storage or access that is used exclusively for statistical purposes.The technical storage or access that is used exclusively for anonymous statistical purposes. Without a subpoena, voluntary compliance on the part of your Internet Service Provider, or additional records from a third party, information stored or retrieved for this purpose alone cannot usually be used to identify you.
Marketing
The technical storage or access is required to create user profiles to send advertising, or to track the user on a website or across several websites for similar marketing purposes.
