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Paramol Tablets

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Paramol Tablets: Key Information

Paramol tablets contain paracetamol and dihydrocodeine, which work together to treat moderate pain that is not relieved by other painkillers such as paracetamol, ibuprofen, or aspirin. It is suitable for short-term relief of pain from conditions like:

  • Headaches
  • Migraines
  • Period pain
  • Toothache and dental pain
  • Back pain
  • Muscular and joint pain
  • Neuralgia

Important Warnings:

  • Paramol should only be used for short-term treatment of moderate pain when other painkillers haven’t worked.
  • Do not use this medicine for more than three days in a row. If you need to take it longer, consult your doctor or pharmacist.
  • The dihydrocodeine in Paramol can be addictive if used for more than three days. This can cause withdrawal symptoms when you stop taking it.
  • If you use Paramol for headaches for more than three days, it may actually worsen your headaches.

Be sure to read this leaflet thoroughly before using the medication. To purchase Paramol online, visit courierpharmacy.co.uk and complete the online consultation form.

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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What Are Paramol Tablets?

Paramol is a pain relief medication containing a combination of paracetamol and dihydrocodeine, known as co-dydramol. It is designed for individuals aged 12 and over who need short-term relief from moderate pain that can’t be managed with paracetamol, ibuprofen, or aspirin alone.

How Do Paramol Tablets Work?

Dihydrocodeine is an opioid analgesic that works by blocking pain signals in the body. This helps to reduce the intensity of pain, providing effective relief.

Important Usage Information

Dihydrocodeine should not be taken for more than 3 days in a row. If your pain persists after 3 days, it’s important to consult a doctor or pharmacist for further guidance.

What Are the Active Ingredients in Paramol Tablets?

Each Paramol tablet contains:

  • 500mg of paracetamol
  • 7.46mg of dihydrocodeine tartrate

What Is Paramol Used For?

Paramol is a painkiller meant for short-term use (up to 3 days) to manage moderate pain when paracetamol, ibuprofen, or aspirin are not enough.

Paramol is effective for pain relief related to:

  • Headaches
  • Migraines
  • Period pain
  • Toothaches
  • Back pain
  • Muscle pain
  • Joint pain
  • Nerve pain

How Does Paramol Work?

Paramol is a fast-acting painkiller that combines two powerful ingredients: paracetamol and dihydrocodeine.

  • Paracetamol is a commonly used painkiller that effectively reduces mild to moderate pain, usually within an hour.
  • Dihydrocodeine is an opioid painkiller that works by blocking pain signals from reaching the brain, reducing the intensity of the pain.

By using both ingredients, Paramol offers a quick and effective solution for pain relief, targeting pain in different ways for faster results.

Dosage Instructions for Paramol Tablets

Adults and Adolescents (16 years and over):

  • Take one or two tablets every 4 to 6 hours.
  • Do not exceed 8 tablets in a 24-hour period.

Adolescents (12–15 years old):

  • Take one tablet every 4 to 6 hours.
  • Do not exceed 4 tablets in a 24-hour period.

Children under 12 years:

  • Not suitable for children under 12 years old.

Special Considerations:

  • It’s best to take Paramol tablets with or after meals.
  • Elderly patients should be cautious when adjusting the dose.
  • If symptoms continue or worsen, consult your doctor or pharmacist.
  • Do not use this medicine for more than 3 consecutive days without consulting a doctor. If longer use is needed, speak with your healthcare provider.
  • Paramol contains dihydrocodeine, which can lead to addiction if used continuously for over three days. Stopping the medication suddenly may cause withdrawal symptoms. Contact your doctor or pharmacist if you think you are experiencing withdrawal.

Overdose Instructions:

  • If you take too many tablets, seek immediate medical advice, even if you feel fine, as there may be a delayed risk of severe liver damage.

Who Should Not Take Paramol?

Paramol contains dihydrocodeine, which can lead to addiction if used for more than three days. Prolonged use can also cause withdrawal symptoms when stopped suddenly.

Using a painkiller for headaches for longer than three days can actually worsen the condition.

Do not take Paramol if you:

  • Are allergic to paracetamol, dihydrocodeine, or any of the other ingredients in the product (check section 6 for a full list).
  • Have diarrhea caused by poisoning or severe watery diarrhea, particularly if accompanied by blood or if you've been on antibiotics (pseudomembranous colitis).
  • Have an alcohol dependence.
  • Have increased pressure inside the head, suffer from seizures, or have acute abdominal conditions.
  • Are taking Monoamine Oxidase Inhibitors (MAOIs) or have taken them in the last 14 days.
  • Are pregnant or breastfeeding.
  • Have breathing difficulties.
  • Suffer from delayed stomach emptying or reduced bowel movement.
  • Are under 18 and have had tonsil or adenoid removal for Obstructive Sleep Apnoea Syndrome.
  • Rapidly metabolize codeine into morphine.

Speak to your doctor or pharmacist before using Paramol if you:

  • Have any allergies.
  • Have asthma (do not take during an asthma attack).
  • Have liver or kidney issues.
  • Have an underactive thyroid.
  • Experience low blood pressure or adrenal problems.
  • Have an enlarged prostate, bowel issues, recent surgery, gallstones, or difficulty urinating.
  • Have myasthenia gravis, a history of irregular heartbeats, or seizures.
  • Have a history of drug use or mood changes.
  • Are elderly.
  • Are considering giving this medicine to a child with any breathing problems.

Drug Interactions:

Be cautious if you are taking any of the following medications:

  • Monoamine oxidase inhibitors (e.g., Pethidine), warfarin (blood thinners), or medications like domperidone or metoclopramide (for nausea).
  • Hydroxyzine (for anxiety), central nervous system depressants, alcohol, anesthetics, or sedatives.
  • Phenothiazines (antipsychotics), diuretics, and high blood pressure medications.
  • Loperamide or kaolin (for diarrhea).
  • Antimuscarinic drugs (e.g., atropine) or neuromuscular blockers (e.g., tracrium).
  • Quinidine (for malaria), mexiletine (for high blood pressure or irregular heartbeat), cisapride, or cimetidine (for reflux).
  • Naloxone (opioid addiction treatment) or naltrexone (used for alcohol addiction).
  • Benzodiazepines or related sedative medications.
  • Flucloxacillin (antibiotic), especially in cases of severe kidney impairment, sepsis, malnutrition, or chronic alcoholism, which can lead to a serious metabolic acidosis.

Special Considerations:

  • If you take a painkiller for headaches for over three days, it could make your headaches worse.

Pregnancy and Breastfeeding:

  • Do not use this medicine if you are pregnant or breastfeeding.

Driving and Operating Machinery:

  • Paramol may cause drowsiness, confusion, blurred vision, dizziness, or even hallucinations. It can impair your ability to drive or use machinery.
  • Do not drive or operate machinery until you know how this medicine affects you.
  • Driving under the influence of this medication can be an offense. However, it’s not considered an offense if:
    • The medicine was taken for a medical or dental issue.
    • You’ve followed the usage instructions.
    • It does not impair your ability to drive safely.

For more details on UK drug driving laws, refer to the UK Drug Driving Law.

What Are the Side Effects of Paramol?

Like all medicines, Paramol can cause side effects, but not everyone will experience them.

If you experience any of the following, stop taking Paramol and seek immediate medical help:

  • Severe allergic reactions such as difficulty breathing, rapid heartbeat, severe skin reactions like itching, redness, peeling, blistering, or swelling of the face.

Contact your doctor if you notice any of these side effects:

  • Unexplained bruising or bleeding, fever, sore throat, or mouth ulcers.
  • Mood changes such as depression, hallucinations, confusion, restlessness, or nightmares.
  • Dizziness, feeling like you are spinning, drowsiness, seizures, involuntary muscle movements, or headaches.
  • Blurred or double vision, or smaller pupils.
  • Slow heartbeat, difficulty breathing, or a suppressed cough.
  • Stomach pain, nausea, constipation, vomiting, dry mouth, loss of bladder control, or diarrhea.
  • Muscle stiffness or pain.
  • Difficulty passing urine or pain when urinating.
  • Loss of libido, low body temperature, excessive sweating, tiredness, or feeling unwell.

How Do I Know If I'm Addicted?

It is unlikely that you will become addicted if you follow the instructions on the pack. However, you should speak with your doctor if:

  • You feel the need to take Paramol for longer than recommended.
  • You need to take more than the suggested dose.
  • You experience withdrawal symptoms when you stop taking the medicine, but feel better when you start it again.

Reporting Side Effects:

If you experience any side effects, consult your doctor, pharmacist, or nurse. This includes any side effects not listed here. You can also report side effects directly through the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.

Does Paramol Interact with Any Medicines?

Interactions with Other Medicines:

Paramol may interact with the following medicines:

  • Monoamine oxidase inhibitors (MAOIs) such as Pethidine.
  • Blood thinners like warfarin.
  • Medications for nausea and vomiting such as domperidone or metoclopramide.
  • Cholesterol-lowering medicines like cholestyramine.
  • Anxiety treatments like hydroxyzine and central nervous system depressants such as alcohol, anesthetics, hypnotics, and sedatives.
  • Antipsychotic drugs like phenothiazines, diuretics, and blood pressure-lowering medications.
  • Diarrhea treatments such as loperamide or kaolin.
  • Neuromuscular blocking drugs such as atropine and tracrium.
  • Medicines for malaria, high blood pressure, or irregular heartbeat, like quinidine and mexiletine, and reflux treatments like cisapride and cimetidine.
  • Medications for opioid addiction such as naloxone or naltrexone.
  • Sedative medicines including benzodiazepines.
  • Flucloxacillin, an antibiotic, which can cause severe blood and fluid imbalances, especially in cases of severe kidney issues, sepsis, malnutrition, or chronic alcoholism.

Take Special Care:

If you use a painkiller for headaches for more than three days, it can worsen the headaches.

Other Medicines and Paramol:

  • Always inform your doctor or pharmacist about any other medicines you are taking, have recently taken, or may take in the future.
  • Using Paramol with opioids, sedative medications, or other similar drugs increases the risk of drowsiness, breathing problems, coma, and even life-threatening conditions. It is important to only consider this combination if no other treatment options are available.
  • If your doctor prescribes Paramol alongside opioids or sedatives, they will carefully manage the dosage and duration of the treatment.
  • Ensure that your doctor knows about all opioids or sedatives you are taking and follow their guidance on dosage. It may be helpful to inform friends or family of the symptoms to watch for. If you notice any concerning signs, contact your doctor immediately.

Paramol FAQs

What is Paramol?

Paramol is a pain relief medication that contains a combination of paracetamol and dihydrocodeine. It is designed for short-term relief of moderate pain when other painkillers like paracetamol, ibuprofen, or aspirin are not enough.

What conditions can Paramol treat?

Paramol can help with moderate pain from a variety of conditions, including:

  • Headaches
  • Migraines
  • Period pain
  • Dental pain
  • Back pain
  • Muscular pain
  • Joint pain
  • Nerve pain

How should I take Paramol?

  • Adults and adolescents aged 16 years and older: Take 1 or 2 tablets every 4 to 6 hours as needed, up to a maximum of 8 tablets in 24 hours.
  • Adolescents aged 12-15: Take 1 tablet every 4 to 6 hours, with a maximum of 4 tablets in 24 hours.
  • Not suitable for children under 12 years.

Can I take Paramol if I am pregnant or breastfeeding?

No, Paramol is not safe during pregnancy or breastfeeding. Consult your doctor for alternative pain relief options.

What are the possible side effects of Paramol?

Common side effects include:

  • Constipation
  • Nausea
  • Drowsiness

Serious side effects may include:

  • Allergic reactions
  • Breathing problems
  • Dizziness
  • Unusual bruising or bleeding

If you experience any severe side effects, seek medical attention immediately.

Can I drive or operate machinery while taking Paramol?

Paramol may cause drowsiness, dizziness, or blurred vision. It is not recommended to drive or operate machinery until you know how this medication affects you.

Can Paramol cause addiction?

Yes, Paramol contains dihydrocodeine, which is an opioid and can be addictive if used for longer than recommended. Follow your doctor's instructions carefully and avoid using it for more than 3 days.

What should I do if I miss a dose of Paramol?

If you miss a dose, take it as soon as you remember. If it’s nearly time for the next dose, skip the missed dose and continue as normal. Do not double the dose.

What should I do if I take too much Paramol?

If you overdose on Paramol, seek medical help immediately, even if you feel fine. Overdose symptoms may include drowsiness, nausea, and difficulty breathing. Excessive paracetamol intake can cause serious liver and kidney damage.

Can I take Paramol with other medications?

Always inform your doctor or pharmacist if you are taking any other medications, especially:

  • MAOIs (e.g., Pethidine)
  • Blood thinners (e.g., warfarin)
  • Anti-nausea medicines (e.g., domperidone)
  • Antidepressants
  • Sedatives

Some medications can interact with Paramol and increase side effects.

Can I take Paramol with Ibuprofen?

Yes, it is safe to take Paramol with Ibuprofen or Aspirin. However, do not take Paramol with other paracetamol-containing products to avoid exceeding the recommended dose.

Can I take Paramol with Amoxicillin?

Yes, it is safe to take Paramol with amoxicillin. However, avoid combining it with other medications unless advised by your doctor.

What should I do if I overdose on Paramol?

If you think you have taken too much Paramol, stop taking it and seek medical advice immediately. Overdose symptoms may include:

  • Drowsiness
  • Dizziness
  • Difficulty breathing
  • Unconsciousness

Can I drink alcohol while taking Paramol?

It is not recommended to drink alcohol while taking Paramol, as alcohol can increase drowsiness and the risk of serious side effects.

How long can I take Paramol?

Paramol should only be used for up to 3 days. If your pain continues after this period, consult your doctor or pharmacist for alternative treatment options.

For more information or to purchase Paramol, visit courierpharmacy.co.uk after completing the online consultation form.

Download patient leaflet

Paramol PIL Medicalmojo.co.uk

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Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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