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Sildenafil 25mg Tablets

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Sildenafil 25mg tablets are a low-dose, effective treatment for erectile dysfunction that works by enhancing blood flow to the penis, helping men achieve and maintain erections.

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Sildenafil 25mg Tablets

Description

 

Product description: Sildenafil 25mg tablets

Sildenafil 25mg tablets offer a reliable and affordable solution for men experiencing erectile dysfunction. Containing the same active ingredient as the well-known brand Viagra, Sildenafil helps improve blood flow to the penis, making it easier to get and maintain an erection when sexually aroused.

This low-dose option is ideal for men who are starting treatment or those who experience side effects at higher doses. It is effective for many users, with benefits including:

  • Rapid onset of action, typically within 30 to 60 minutes
  • Duration of effect up to 6 hours, allowing flexibility in timing
  • Well-established safety profile with minimal side effects at this dose

Sildenafil 25mg tablets are available by prescription from courierpharmacy.co.uk following a quick online consultation with a licensed healthcare professional. Discreet packaging and fast delivery options ensure privacy and convenience.

 

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4 tablets, 8 tablets, 12 tablets, 16 tablets, 20 tablets

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Safdar Ali
BSc Pharmacy

Pharmacist


What are Sildenafil 25mg tablets?

Sildenafil 25mg tablets are a trusted, effective treatment for erectile dysfunction (ED), helping men regain confidence and enjoy a fulfilling sex life. This detailed guide covers everything you need to know about Sildenafil 25mg tablets—from how they work and dosage advice to safety tips and common questions. Whether you’re new to ED treatments or considering Sildenafil for the first time, this article will walk you through all the essentials in a friendly, straightforward way.

Five key takeaways

  • Sildenafil 25mg tablets are a safe, effective ED treatment with rapid onset.
  • They work by increasing blood flow to penile tissue during sexual arousal.
  • Effects last 4 to 6 hours, providing a useful treatment window.
  • The 25mg dose is suitable for those new to treatment or sensitive to side effects.
  • Available online at courierpharmacy.co.uk with confidential delivery.

Overview: Sildenafil 25mg tablets

Erectile dysfunction affects many men worldwide, impacting quality of life and relationships. Sildenafil 25mg tablets provide a proven, accessible option to manage ED symptoms effectively. By relaxing blood vessels in the penis, Sildenafil improves blood flow, which is essential for achieving a firm erection [1] [2].

Starting with a 25mg dose allows healthcare providers to assess tolerance and effectiveness, with options to adjust dosage if necessary. This flexibility helps balance efficacy with minimising potential side effects [3].

Infographic from courierpharmacy.co.uk showing how sildenafil 25mg tablets work, including dosage, side effects, warnings, and FAQs in a steampunk-inspired design.

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Active ingredient: Sildenafil 25mg tablets

The active ingredient in Sildenafil 25mg tablets is sildenafil citrate, a phosphodiesterase type 5 (PDE5) inhibitor. Sildenafil works by blocking the PDE5 enzyme, which normally breaks down cyclic guanosine monophosphate (cGMP)—a molecule that promotes relaxation of smooth muscle and blood vessel dilation in the penis [2] [4].

By inhibiting PDE5, Sildenafil allows cGMP to accumulate, leading to improved blood flow and enabling an erection in response to sexual stimulation. This mechanism is the basis for Sildenafil’s effectiveness in treating erectile dysfunction.

The 25mg tablets contain a lower dose of sildenafil citrate, making them suitable for men who need a gentler start or experience side effects at higher doses [3].

Infographic from courierpharmacy.co.uk explaining why it’s best to start with sildenafil 25mg tablets, showing the benefits of safety, effectiveness, and side effect management in a steampunk-inspired laboratory setting. Courierpharmacy.co.uk divider

What are sildenafil 25mg tablets used for?

Sildenafil 25mg tablets are primarily prescribed to treat erectile dysfunction (ED), a condition where men have difficulty achieving or maintaining an erection sufficient for sexual activity. ED can result from various causes including cardiovascular disease, diabetes, stress, or age-related changes [1]. In addition to ED, Sildenafil is sometimes used off-label for conditions such as pulmonary arterial hypertension, but the 25mg tablet strength is specifically targeted for ED treatment [2]. By improving blood flow to the penis during sexual arousal, Sildenafil helps restore sexual function and confidence, enhancing quality of life. Illustration from courierpharmacy.co.uk showing a thoughtful man and a supportive woman sitting together in a steampunk-inspired bedroom, with the message “Sildenafil 25mg is the starting dose for erectile dysfunction.” Courierpharmacy.co.uk divider

How do sildenafil 25mg tablets work?

Sildenafil belongs to the class of medications known as PDE5 inhibitors. Under normal circumstances, sexual stimulation leads to the release of nitric oxide in the penis, which activates an enzyme that produces cGMP. This molecule causes smooth muscle relaxation and vasodilation, allowing blood to fill the penile chambers and create an erection [2] [4].

However, PDE5 breaks down cGMP, limiting the duration of an erection. Sildenafil blocks PDE5, preventing this breakdown and allowing cGMP to accumulate, sustaining the erection during sexual activity.

It’s important to note that Sildenafil does not cause an erection on its own; sexual arousal is still necessary for the medication to work. The sildenafil 25mg dose provides a mild but effective boost to this natural process, making it suitable for many men starting treatment [3].

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How to take sildenafil 25mg tablets?

Sildenafil 25mg tablets should be taken as directed by your healthcare provider, usually around one hour before planned sexual activity.

Infographic from courierpharmacy.co.uk detailing sildenafil 25mg dosage instructions, starting dose advice, and dosing frequency in a steampunk-inspired design.  

Swallow the tablet whole with a glass of water.

For best results, take Sildenafil on an empty stomach, as food—especially high-fat meals—can slow down absorption and delay the onset of action.

Do not take more than one tablet in a 24-hour period. If you find the 25mg dose effective but experience side effects, consult your doctor about adjusting your dose.

Avoid grapefruit juice, as it can interfere with how the medication works [1] [2].

Dr. Rosalind Jex of courierpharmacy.co.uk stands in her steampunk lab, wearing a chef’s hat, holding a spoon and a clock-shaped plate with a steak, reminding readers to take sildenafil on an empty stomach for best results. A medical infographic from courierpharmacy.co.uk Courierpharmacy.co.uk divider

Warnings and precautions: Sildenafil 25mg tablets

Before starting Sildenafil 25mg tablets, discuss your full medical history with your healthcare provider.

Do not take Sildenafil if you use nitrate medications for chest pain, as this combination can cause a dangerous drop in blood pressure.

The tablets are not suitable for those with severe heart or liver problems, recent history of stroke or heart attack, or certain rare inherited eye diseases.

Always inform your doctor if you have low blood pressure, bleeding disorders, or anatomical deformities of the penis

Sildenafil 25 mg tablets are only licensed for men and should not be used by women [1] [2] [3].

Infographic from courierpharmacy.co.uk outlining important warnings and precautions for sildenafil 25mg tablets, including contraindications, heart conditions, and drug interactions.   Courierpharmacy.co.uk divider

Side effects of sildenafil 25mg tablets

Most side effects of Sildenafil 25mg tablets are mild and temporary.

Infographic from courierpharmacy.co.uk showing common, uncommon, and rare side effects of sildenafil 25mg tablets, including headache, visual disturbances, facial flushing, and more, with advice to consult a doctor if severe symptoms occur.  

Common side effects include headache, flushing, indigestion, acid reflux, nasal congestion, dizziness, nausea, and visual disturbances (such as a blue tint to vision or blurred vision).

Less commonly, some may experience muscle aches, rash, or palpitations.

Rare but serious side effects include chest pain, prolonged or painful erections (priapism), sudden hearing or vision loss, and allergic reactions. If you experience any severe or persistent symptoms, seek medical attention immediately [4] [2].

Dr. Rosalind Jex of courierpharmacy.co.uk stands in her steampunk laboratory, holding a steaming mug and a tissue, beside a list of common sildenafil side effects such as headache and dizziness, highlighting the importance of being aware of potential reactions. Courierpharmacy.co.uk divider

Drug interactions with sildenafil 25mg tablets

Sildenafil 25mg tablets, used to treat erectile dysfunction, may interact with various other medications. Such interactions can alter the effectiveness of sildenafil or increase the risk of side effects.

Do not use alongside nitrate medications (e.g., for angina) or medications called guanylate cyclase stimulators (such as riociguat), as this can cause a dangerous drop in blood pressure.

Use caution with alpha-blockers, antihypertensives, and certain antifungals or antibiotics.

Tell your doctor about all medicines and supplements you are taking, including over-the-counter remedies. Alcohol can worsen side effects, and grapefruit juice may increase the risk of adverse reactions [2], [3], [7], [8].

Common drug interactions

  • Nitrate Medications:
    • Examples: Nitroglycerin, isosorbide dinitrate, isosorbide mononitrate
    • Effect: Can cause a severe, life-threatening drop in blood pressure
    • Note: Do not use sildenafil with any form of nitrate medication.
  • Alpha-Blockers:
    • Examples: Doxazosin, tamsulosin
    • Effect: May lead to a significant drop in blood pressure, resulting in dizziness or fainting
    • Note: Use only under medical supervision.
  • Antihypertensives:
    • Examples: Amlodipine, enalapril
    • Effect: Enhanced blood pressure-lowering effects that could increase the risk of hypotension
    • Note: Regular blood pressure monitoring is advised.
  • Protease Inhibitors (for HIV):
    • Examples: Ritonavir, saquinavir
    • Effect: Can raise blood levels of sildenafil, increasing the risk of side effects
    • Note: A dosage adjustment of sildenafil may be necessary.
  • Antifungal Medications:
    • Examples: Ketoconazole, itraconazole
    • Effect: May increase sildenafil levels in the blood
    • Note: A dosage adjustment might be required.
  • Antibiotics:
    • Examples: Erythromycin, clarithromycin
    • Effect: Can elevate plasma levels of sildenafil, potentially enhancing side effects
    • Note: Consult your healthcare provider for possible dosage adjustments.
  • Rifampin (for tuberculosis):
    • Effect: May decrease the effectiveness of sildenafil due to faster metabolism
    • Note: A higher dose of sildenafil might be needed.
  • Other ED Medications:
    • Examples: Tadalafil, vardenafil
    • Effect: Combining these can increase the risk of severe side effects, such as a prolonged erection (priapism)
    • Note: Do not mix sildenafil with other erectile dysfunction treatments.
  • Grapefruit Juice:
    • Effect: Can raise blood levels of sildenafil, intensifying both its effects and side effects
    • Note: Avoid consuming grapefruit juice while taking sildenafil.
  • Alcohol:
    • Effect: May increase the likelihood of side effects like dizziness and further lower blood pressure
    • Note: Limit alcohol intake while using sildenafil.

Special Considerations

  • Age and Medical Conditions: Older adults and individuals with certain health issues may be more sensitive to drug interactions. Always share your full medical history with your healthcare provider.
  • Monitoring: Regular check-ups are recommended when sildenafil is taken along with other medications.
  • Emergency Situations: Seek immediate medical attention if you experience severe side effects such as chest pain, severe dizziness, or an erection that lasts too long.
Dr. Rosalind Jex, brand ambassador for courierpharmacy.co.uk, stands in a steampunk laboratory holding two flasks labelled “Nitrates” and “Sildenafil”, warning not to mix them. The scene highlights the importance of safety precautions before taking sildenafil. An infographic by courierpharmacy.co.uk

Courierpharmacy.co.uk divider

FAQ: Sildenafil 25mg tablets

What is sildenafil 25mg used for?

Sildenafil 25mg tablets are used to treat erectile dysfunction by improving blood flow to the penis during sexual arousal [1].

How quickly does sildenafil 25mg work?

It usually takes 30 to 60 minutes to work, but may take longer if taken with food [4].

How long does sildenafil 25mg last?

The effect typically lasts 4 to 6 hours [10].

Can I take sildenafil 25mg every day?

Only if prescribed. Do not exceed one dose in 24 hours [2].

Is sildenafil 25mg the same as Viagra?

Yes, both contain sildenafil citrate as the active ingredient [4].

Can I drink alcohol while taking sildenafil 25mg?

It’s best to limit alcohol, as it can make side effects more likely and reduce effectiveness [7].

What should I do if sildenafil 25mg doesn’t work?

Consult your doctor; they may recommend a dose adjustment or alternative treatment [3].

What are the alternatives to sildenafil 25mg?

Other PDE5 inhibitors like tadalafil or vardenafil, vacuum pumps, or counselling for psychological causes [11].

Can women use sildenafil 25mg?

Sildenafil is not licensed for use in women for sexual problems in the UK [1].

Can I take sildenafil 25mg with food?

Yes, but it may take longer to work if taken after a meal [4].

Will sildenafil 25mg make my erection bigger?

It helps you achieve your natural maximum erection size, but won’t make it bigger than normal [6].

Is sildenafil 25mg cheaper than Viagra?

Yes, it’s the generic form and is more affordable [9].

Can I take sildenafil 25mg with blood thinners?

Consult your doctor first, as interactions may occur [8].

Can I take sildenafil 25mg if I have heart problems?

Only under medical supervision. Do not use if you take nitrates or have certain heart conditions [2].

What should I do if I get side effects?

Contact your doctor if side effects persist or are severe [4].

Can I buy sildenafil 25mg over the counter?

No, it’s prescription-only, but Viagra Connect (containing sildenafil) is available after pharmacist assessment [4].

Can I take sildenafil 25mg with other ED medications?

No, never combine ED medications unless directed by your doctor [2].

Is sildenafil 25mg safe for long-term use?

It can be used long-term if prescribed, with regular medical reviews [3].

Can sildenafil 25mg be used for conditions other than ED?

It is sometimes used off-label for other conditions, but only under specialist supervision [2].

How should I store sildenafil 25mg tablets?

Store at room temperature, away from moisture and out of reach of children [4].

Courierpharmacy.co.uk divider

Disclaimer: This article is for informational purposes only and does not replace professional medical advice.

References

  1. NHS. (2024). Erection problems (erectile dysfunction). Available at: https://www.nhs.uk/conditions/erection-problems-erectile-dysfunction/ (Accessed: 25 October 2025).
  2. BNF. (2025). Sildenafil. Available at: https://bnf.nice.org.uk/drugs/sildenafil/ (Accessed: 25 October 2025).
  3. NICE. (2025). Erectile dysfunction: management. Available at: https://cks.nice.org.uk/topics/erectile-dysfunction/management/management/ (Accessed: 25 October 2025).
  4. Electronic Medicines Compendium (EMC). (2025). Viagra 50 mg film-coated tablets. Available at: https://www.medicines.org.uk/emc/product/3172/pil#gref (Accessed: 25 October 2025).
  5. Courier Pharmacy. (2025). Can Viagra cause blood clots? Available at: https://courierpharmacy.co.uk/can-viagra-cause-blood-clots-2/ (Accessed: 25 October 2025).
  6. Courier Pharmacy. (2025). Can Viagra make you bigger? Available at: https://courierpharmacy.co.uk/can-viagra-make-you-bigger-2/ (Accessed: 25 October 2025).
  7. Courier Pharmacy. (2025). Can you drink alcohol while taking sildenafil? Available at: https://courierpharmacy.co.uk/can-you-drink-alcohol-while-taking-sildenafil/ (Accessed: 25 October 2025).
  8. Courier Pharmacy. (2025). Can you take Viagra with blood thinners? Available at: https://courierpharmacy.co.uk/can-you-take-viagra-with-blood-thinners-2/ (Accessed: 25 October 2025).
  9. Courier Pharmacy. (2025). Is it cheaper to buy sildenafil from Tesco or Boots? Available at: https://courierpharmacy.co.uk/is-it-cheaper-to-buy-sildenafil-from-tesco-or-boots/ (Accessed: 25 October 2025).
  10. Courier Pharmacy. (2025). How long does sildenafil last for and how long does it take to work? Available at: https://courierpharmacy.co.uk/how-long-does-sildenafil-last-for-and-how-long-does-it-take-to-work/ (Accessed: 25 October 2025).
  11. Courier Pharmacy. (2025). Sildenafil vs tadalafil: which one is right for you? Available at: https://courierpharmacy.co.uk/sildenafil-vs-tadalafil-which-one-is-right-for-you/ (Accessed: 25 October 2025).Courierpharmacy.co.uk divider

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.3172.pdf

Checked By
Safdar Ali
BSc Pharmacy

Pharmacist


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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