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Dutasteride 0.1%, minoxidil 5% in Trichosol topical hair loss solution

from£29.99

A personalised topical hair loss solution containing dutasteride 0.1% and minoxidil 5% in a Trichosol base free from propylene glycol and alcohol. Designed for adults who need a focused two-ingredient approach targeting the hormonal and circulatory drivers of pattern hair loss — with dutasteride at a clinically considered mid-range concentration, in a base their scalp can genuinely tolerate. Applied using a dropper bottle at night and washed off in the morning.

  • Propylene glycol FREE
  • Alcohol FREE
  • Two active ingredients
  • Pack size: 30ml bottle, around one month’s supply
  • Expiry date: 180 days from compounding date
  • Prescription only

TREATS:

Hair Loss

FORMAT:

Topical solution

Availability:

In stock

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Dutasteride 0.1%, minoxidil 5% in Trichosol topical hair loss solution
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Description

Dutasteride 0.1%, Minoxidil 5% in Trichosol (propylene glycol and alcohol FREE) topical hair loss solution — Product description

Dutasteride 0.1%, minoxidil 5% in Trichosol topical hair loss solution is a dual action formulation that is mild on the skin but tough on hair loss.

The problem with hair loss

Hair loss is easy to dismiss — until it happens to you. The visible signs are familiar: thinning at the crown, a wider parting, a hairline moving in the wrong direction. The less visible impact is often harder to carry. Confidence drops. Self-consciousness builds. The worry that things are getting worse — and that nothing tried so far has made a real difference — becomes part of daily life.

The problem with standard treatments

For many people, the frustration goes beyond the hair loss itself. It is about the experience of trying to treat it.

Standard topical hair loss liquids sting on application. The alcohol hits the scalp before the product has had a chance to absorb. The propylene glycol leaves a tight, uncomfortable residue that lingers for hours. After a few weeks of that, skipping a night feels less like failure and more like self-preservation.

Skipping nights is exactly what stops hair loss treatment from working.

Why this two-ingredient combination?

Pattern hair loss has more than one driver. DHT miniaturises follicles through the hormonal pathway. Poor scalp circulation and reduced follicle activity then accelerate visible thinning.

This formula addresses both dimensions directly. Dutasteride 0.1% targets the hormonal driver at a clinically considered mid-range compounded strength — blocking both type 1 and type 2 5-alpha reductase for a more comprehensive approach to DHT suppression. Minoxidil 5% stimulates follicle activity and improves scalp circulation. Together, they form a considered two-ingredient approach — not a default combination, but a formula selected because clinical assessment and, where used, TrichoTest results indicate this is the most appropriate treatment for the individual.

Why Trichosol?

The Trichosol base removes propylene glycol and alcohol entirely. No stinging. No tight scalp after application. No alcohol odour. Just two active ingredients, carried in a vehicle the scalp is far more likely to tolerate comfortably — applied night after night, for as long as treatment is needed.

Why 0.1% dutasteride?

The dutasteride concentration in this formula is 0.1%. This is a clinically considered mid-range compounded strength. The prescriber selects it when clinical assessment indicates this is the most appropriate concentration — whether as a starting point for patients whose profile suggests a moderate to strong anti-androgen requirement, or as an ongoing concentration supported by TrichoTest results. The concentration is not a default. It is a clinical decision made for you specifically.

A medically responsible route

At Courier Pharmacy, treatment starts with a proper assessment. Suitability is checked. The decision to prescribe this compounded solution is a clinical one — based on your scalp, your history, and your goals.

  • Prescription-only compounded Trichosol solution for pattern hair loss
  • Propylene glycol free, alcohol free base for a gentler daily experience
  • Dutasteride 0.1%, minoxidil 5% — a clinically considered two-ingredient combination
  • Reviewed for suitability by a UK-qualified prescriber

Additional information

Quantity

1 x 30ml, 2 x 30ml, 3 x 30ml, 4 x 30ml, 5 x 30ml, 6 x 30ml

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

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Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Safdar Ali
BSc Pharmacy

Pharmacist


What is Dutasteride 0.1%, Minoxidil 5% in Trichosol topical hair loss solution?

This compounded topical hair loss solution contains dutasteride 0.1% and minoxidil 5% in a Trichosol base that is completely free from propylene glycol and alcohol. It is designed for adults with pattern hair loss who need a focused two-ingredient approach — targeting the hormonal driver of hair loss at a mid-range dutasteride concentration and supporting follicle activity — particularly those who need a gentler base because standard topical products have caused irritation, or those whose clinical profile indicates this combination is the most appropriate starting point or next step.

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  • Two active ingredients working together to target DHT and support follicle activity
  • Propylene glycol free, alcohol free Trichosol base for a more comfortable daily experience
  • Dutasteride at 0.1%, minoxidil at 5% — a clinically considered mid-range combination
  • May suit people with androgenetic alopecia with a moderate to strong anti-androgen requirement whose scalps have reacted to standard topical bases
  • Safe prescribing still matters — hair loss treatment needs proper screening, review, and follow-up
  • Part of the Gro hair loss range, designed for personalised treatment at less than £1 per day

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Pattern hair loss is personal

Pattern hair loss is common, but that does not make it any less personal. Many people first notice extra shedding, reduced density, or a hairline that seems to be quietly retreating. Many then try a product that does not match their biology, see little result, and quietly give up — not because treatment cannot work, but because they were never on the right treatment to begin with.

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A formula for people who need a mid-range anti-androgen approach in a gentler base

This Trichosol solution is aimed at people who need a carefully considered two-ingredient approach — addressing the hormonal and circulatory drivers of pattern hair loss with dutasteride at a mid-range concentration — in a base their scalp can genuinely tolerate. It is particularly relevant for those whose TrichoTest results indicate a moderate to strong anti-androgen requirement alongside a strong minoxidil response profile, and those who have previously reacted to alcohol or propylene glycol-based products.

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The goal of treatment

Hair loss affects more than appearance. It chips away at confidence. It makes ordinary moments feel oddly loaded — a harsh bathroom mirror, a photo taken from an unexpected angle, a windy day when you would rather not think about what is visible.

The goal of treatment is not perfection. It is to slow loss, support healthier growth, and help you feel more in control — with a plan that addresses the full picture at the most clinically appropriate strength and a base that makes daily use something you can actually stick to.

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The Trichosol advantage

When the vehicle is the problem

For patients who have reacted badly to standard topical hair loss solutions, the problem is not always the active ingredients. Often it is the vehicle carrying them. Alcohol causes stinging on application and dries the scalp significantly over time. Propylene glycol is a common cause of contact irritation, particularly in patients with already sensitive or reactive scalps — and it is a standard excipient in most off-the-shelf hair loss products.

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What Trichosol removes

The Trichosol base removes both of these excipients entirely. The result is a solution that absorbs without stinging, does not dry the scalp, and does not leave the tight or uncomfortable residue that causes so many people to abandon their routine. The active ingredients are unchanged. Only the vehicle is different — and sometimes that difference is everything.

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Why tolerability drives outcomes

A treatment only works if you use it consistently. If the daily experience of applying it is uncomfortable, consistency breaks down. The Trichosol base exists to remove that barrier — making it possible to maintain the kind of steady, sustained daily routine that a two-ingredient hair loss formula requires. Anything that makes consistent application more achievable directly improves the chances of a good outcome.

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Why the Trichosol vehicle matters

The Trichosol base is clinically relevant as well as practically comfortable. It removes the excipients most likely to cause scalp irritation — making it possible for patients to apply their treatment consistently, which is one of the most important factors in whether any hair loss treatment succeeds over time.

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Why compounding?

What compounding means

Compounding means a medicine is prepared to order by a licensed pharmacy for an individual patient. It is not a mass-produced one-size-fits-all product. In the UK, this sits within a regulated framework and should only be supplied when clinically appropriate.

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Why compounding matters for this formula

Some people choose this compounded solution because no standard licensed product combines dutasteride at 0.1% and minoxidil in a Trichosol base — and this specific combination, at a mid-range dutasteride concentration, in a vehicle the scalp can actually tolerate, is what their clinical profile requires. Others come to compounding because standard topical bases have caused irritation and they need their two active ingredients delivered in a gentler vehicle. Others want the clinical flexibility to start with this combination and expand or adjust their formula over time.

The Trichosol base addresses the tolerability concern directly. It removes both propylene glycol and alcohol — the two most common causes of topical scalp irritation — without reducing the effectiveness of either active ingredient.

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Personalised medicine in practice

Hair loss is not identical from one person to the next. The right combination of ingredients, concentrations, and vehicle for one patient is not right for another. Compounding makes it possible to prescribe dutasteride 0.1% and minoxidil 5% together in a Trichosol base — a formulation that simply does not exist in any standard licensed product — when clinical assessment indicates that this is the most appropriate approach. The medicine is shaped around the patient, not the other way around.

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Why this two-ingredient combination can be the right choice

Some patients need both mechanisms addressed — DHT suppression and follicle stimulation — at a mid-range dutasteride concentration. Unlike finasteride, dutasteride blocks both type 1 and type 2 5-alpha reductase, delivering a more comprehensive reduction in DHT. Think of dutasteride as taking the foot off the brake — more completely than finasteride can. Minoxidil then works alongside it, stimulating follicle activity and improving scalp blood flow. For patients whose TrichoTest results indicate a moderate to strong anti-androgen requirement alongside a strong minoxidil response via the SULT1A1 pathway, this two-ingredient Trichosol combination may be the most clinically efficient approach.

If tretinoin or other ingredients would add further benefit, or if dutasteride needs to be adjusted over time, TrichoTest and clinical assessment will guide that decision. Compounding makes either path possible.

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TrichoTest: personalising the approach

TrichoTest reduces guesswork. It is a pharmacogenetic test that analyses 26 genetic polymorphisms linked to nine key treatment pathways relevant to hair loss. Rather than prescribing from standard protocols alone, TrichoTest combines your genetic profile with your medical history to predict which ingredients, dosages, and delivery methods are most likely to work for your biology.

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How the TrichoTest informs this formula

This two-ingredient formula draws on multiple TrichoTest pathways simultaneously. The sulphotransferase (SULT1A1) pathway predicts minoxidil response — patients with high SULT1A1 expression are strong responders to minoxidil and may benefit particularly from its inclusion at 5%. The anti-androgen metabolism pathway identifies how effectively a patient responds to dutasteride — and whether 0.1% is the most appropriate concentration for their genetic profile.

TrichoTest can identify all of these factors before treatment begins — allowing the prescriber to arrive at the mid-range dutasteride concentration with clinical confidence, rather than defaulting to it or arriving at it only after months of trial and adjustment.

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How the TrichoTest informs this formula more broadly

If TrichoTest identifies that a different dutasteride concentration — lower or higher — would be more appropriate for the individual’s anti-androgen requirement, the prescriber can adjust accordingly. If results suggest that finasteride might be more appropriate than dutasteride, or that tretinoin or additional ingredients would add meaningful benefit, the prescriber can incorporate these from the outset or over time.

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The nine pathways TrichoTest analyses

  • Prostaglandins and sulphotransferase — how you process minoxidil and latanoprost
  • Anti-inflammatory response — your reaction to glucocorticoids and immunomodulators
  • Anti-androgen metabolism — how effectively you respond to dutasteride, finasteride, and 17?-oestradiol
  • Circulation stimulation — response to vasodilators
  • Collagen synthesis capacity
  • Insulin-like Growth Factor (IGF-1) response
  • Vitamin absorption — A, B7, B9, B12, C, D, E
  • Mineral absorption — zinc, magnesium, iron, selenium
  • Antioxidant needs and oxidative stress profile

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Beyond ingredient selection

TrichoTest also identifies nutritional gaps and metabolic factors that affect hair health independently of topical treatment. If genetic variants reduce zinc or iron absorption, the prescriber can recommend targeted supplementation alongside this Trichosol formula — moving treatment from guesswork towards something shaped by your actual biology.

TrichoTest does not guarantee results, but it gives the prescriber better information to decide whether this specific two-ingredient Trichosol formula at 0.1% dutasteride is right for you, or whether something different would serve you better.

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The Gro hair loss range

What is the Gro brand?

Gro is the compounded hair loss range created by Courier Pharmacy and Medical Mojo. It exists because hair loss treatment should not feel one-size-fits-all.

Some people want a traditional liquid spray — direct, efficient, and familiar. Some prefer a foam. Others need an alcohol-free and propylene glycol-free base because their scalp reacts to standard excipients. Gro brings those options together under one brand, matching treatment to the person using it, not the other way around.

Each Gro product comes in a 30ml bottle designed to last one month. Every option costs £29.99 for up to three active ingredients — less than £1 a day.

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Why Gro is different

Gro was built around three practical goals:

  • Choice of formulation: topical liquid, topical foam, or Trichosol solution (propylene glycol free and alcohol free)
  • Personalisation: single, dual, and triple-ingredient combinations across multiple concentrations
  • Better tolerability: every format is designed to reduce the friction that stops people from maintaining their routine

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The three formulation types

  1. Topical hair loss liquid — a traditional spray solution containing alcohol and propylene glycol. Well-established, with efficient scalp penetration. Chosen by patients who want a direct, familiar format.
  2. Hair loss foam — lighter, faster-drying, and easier to apply without dripping. Chosen by patients who want clinical results in a format that fits more easily into daily life.
  3. Trichosol topical solution — propylene glycol free and alcohol free. Designed for patients with sensitive or reactive scalps who need a gentler base. This is the formulation described on this page.

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Ingredients used across the Gro range

Depending on the product selected, Gro formulations may include:

  • Dutasteride
  • Finasteride
  • Minoxidil 5%
  • Tretinoin 0.01%

These can be prescribed alone or in combination, and at varying concentrations, depending on the individual treatment plan.

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Gro product options

The Gro range includes the following compounded hair loss options, each supplied as a 30ml one-month bottle at £29.99.

Dutasteride + Minoxidil + Tretinoin
  • Dutasteride 0.05%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Dutasteride 0.05%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Dutasteride 0.05%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
  • Dutasteride 0.1%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Dutasteride 0.1%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Dutasteride 0.1%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
  • Dutasteride 0.2%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Dutasteride 0.2%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Dutasteride 0.2%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
Dutasteride only
  • Dutasteride 0.05% — topical liquid
  • Dutasteride 0.05% — topical foam
  • Dutasteride 0.05% in Trichosol — topical solution
  • Dutasteride 0.1% — topical liquid
  • Dutasteride 0.1% — topical foam
  • Dutasteride 0.1% in Trichosol — topical solution
  • Dutasteride 0.2% — topical liquid
  • Dutasteride 0.2% — topical foam
  • Dutasteride 0.2% in Trichosol — topical solution
Finasteride only
  • Finasteride 0.05% — topical liquid
  • Finasteride 0.05% — topical foam
  • Finasteride 0.05% in Trichosol — topical solution
  • Finasteride 0.1% — topical liquid
  • Finasteride 0.1% — topical foam
  • Finasteride 0.1% in Trichosol — topical solution
  • Finasteride 0.2% — topical liquid
  • Finasteride 0.2% — topical foam
  • Finasteride 0.2% in Trichosol — topical solution
Minoxidil only
  • Minoxidil 5% — topical liquid
  • Minoxidil 5% — topical foam
  • Minoxidil 5% in Trichosol — topical solution
Minoxidil + Tretinoin
  • Minoxidil 5%, tretinoin 0.01% — topical liquid
  • Minoxidil 5%, tretinoin 0.01% — topical foam
  • Minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
Finasteride + Minoxidil + Tretinoin
  • Finasteride 0.05%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Finasteride 0.05%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Finasteride 0.05%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
  • Finasteride 0.1%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Finasteride 0.1%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Finasteride 0.1%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
  • Finasteride 0.2%, minoxidil 5%, tretinoin 0.01% — topical liquid
  • Finasteride 0.2%, minoxidil 5%, tretinoin 0.01% — topical foam
  • Finasteride 0.2%, minoxidil 5%, tretinoin 0.01% in Trichosol — topical solution
Dutasteride + Minoxidil
  • Dutasteride 0.05%, minoxidil 5% — topical liquid
  • Dutasteride 0.05%, minoxidil 5% — topical foam
  • Dutasteride 0.05%, minoxidil 5% in Trichosol — topical solution
  • Dutasteride 0.1%, minoxidil 5% — topical liquid
  • Dutasteride 0.1%, minoxidil 5% — topical foam
  • Dutasteride 0.1%, minoxidil 5% in Trichosol — topical solution
  • Dutasteride 0.2%, minoxidil 5% — topical liquid
  • Dutasteride 0.2%, minoxidil 5% — topical foam
  • Dutasteride 0.2%, minoxidil 5% in Trichosol — topical solution
Finasteride + Minoxidil
  • Finasteride 0.05%, minoxidil 5% — topical liquid
  • Finasteride 0.05%, minoxidil 5% — topical foam
  • Finasteride 0.05%, minoxidil 5% in Trichosol — topical solution
  • Finasteride 0.1%, minoxidil 5% — topical liquid
  • Finasteride 0.1%, minoxidil 5% — topical foam
  • Finasteride 0.1%, minoxidil 5% in Trichosol — topical solution
  • Finasteride 0.2%, minoxidil 5% — topical liquid
  • Finasteride 0.2%, minoxidil 5% — topical foam
  • Finasteride 0.2%, minoxidil 5% in Trichosol — topical solution

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In simple terms

Gro makes personalised hair loss treatment accessible and liveable.

You get a 30ml bottle for one month, £29.99 pricing, up to three active ingredients at a concentration chosen for you, and a choice of liquid, foam, or Trichosol alcohol-free and propylene glycol-free solution. If you want a treatment that fits your scalp, your sensitivities, and your treatment history — not a generic protocol — the Gro range gives you more than one route without making the choice unnecessarily complicated.

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Buy Dutasteride 0.1%, Minoxidil 5% in Trichosol (prescription only)

This is a Prescription Only Medicine. You can request it from courierpharmacy.co.uk by completing a quick online consultation, reviewed by a UK-qualified prescriber for suitability and safety. If appropriate, Courier Pharmacy will dispense the compounded Trichosol solution and deliver it discreetly.

  1. Complete the online consultation
  2. Prescriber reviews your answers for suitability and safety
  3. Prescription issued if clinically appropriate
  4. Dispensed and delivered discreetly to your door

If the treatment is not suitable, this will be explained clearly and the next best option may be suggested.

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Summary

  • Prescription-only compounded two-ingredient treatment for pattern hair loss
  • Targets DHT via dutasteride and supports follicle activity via minoxidil
  • Propylene glycol free, alcohol free Trichosol base for better scalp tolerability
  • Dutasteride at 0.1% — a clinically considered mid-range concentration — minoxidil at 5%
  • May help patients with a moderate to strong anti-androgen requirement or those who have not tolerated standard topical bases
  • Good outcomes depend on consistency, review, and realistic expectations
  • Comes in a convenient 30ml bottle designed to last around one month, at less than £1 per day

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Dutasteride 0.1%, Minoxidil 5% in Trichosol — Active ingredients

Dutasteride 0.1%

Dutasteride is a 5-alpha reductase inhibitor. Unlike finasteride, which selectively blocks type 2 5-alpha reductase, dutasteride blocks both type 1 and type 2 — delivering a more comprehensive reduction in the conversion of testosterone to dihydrotestosterone, or DHT, the key hormonal driver of androgenetic alopecia in susceptible hair follicles. At 0.1%, this is a clinically considered mid-range concentration — not a default, but a considered choice based on the individual's profile, history, and TrichoTest results where used. The concentration is not a compromise. It is a clinical decision made for the individual.

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Minoxidil 5%

Minoxidil is a topical vasodilator and follicle stimulant. It supports hair growth by prolonging the anagen (growth) phase of the hair cycle, improving blood supply to follicles, and stimulating follicle cells to produce thicker, healthier hair. At 5%, this is the standard compounded concentration for adults with pattern hair loss.

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Why the Trichosol vehicle matters

The Trichosol base is also clinically relevant. Standard hair loss solutions typically rely on alcohol and propylene glycol as delivery vehicles — both of which are common causes of scalp irritation. The Trichosol base removes these entirely, making it possible for patients to apply this two-ingredient formula comfortably and consistently, which is one of the most important factors in whether any hair loss treatment succeeds over time.

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What is the Dutasteride 0.1%, Minoxidil 5% in Trichosol solution used for?

Pattern hair loss in men and women

This product treats pattern hair loss, also called androgenetic alopecia. In men, this often appears as a receding hairline or thinning at the crown. In women, it may present as diffuse thinning or a widening parting. The aim is to support hair retention and encourage healthier growth where clinically appropriate.

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The problems of hair loss

The practical problem is visible thinning. The internal problem is the loss of confidence that builds quietly alongside it. The deeper issue is that people should not have to feel dismissed or left to navigate treatment alone for something that so clearly affects daily life.

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Who this formula is for

Some patients come to this formula because their clinical profile indicates that both drivers of hair loss — hormonal and circulatory — need to be addressed with dutasteride's dual-pathway DHT suppression at a mid-range concentration, in a base their scalp can actually tolerate. Others arrive because their TrichoTest results demonstrate both a moderate to strong anti-androgen requirement and strong SULT1A1 activity, making this two-ingredient Trichosol combination the most clinically efficient approach. Others still come because previous standard topical products caused too much irritation to use consistently — and the Trichosol base removes that barrier while dutasteride at 0.1% addresses their specific anti-androgen needs. In all cases, a compounded Trichosol solution at dutasteride 0.1% and minoxidil 5% offers a more considered, personalised path than anything available off the shelf.

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How does the Dutasteride 0.1%, Minoxidil 5% in Trichosol solution work?

Pattern hair loss is driven by multiple overlapping processes. This formula targets two of the most important directly.

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Dutasteride: blocking the hormonal signal more completely

In pattern hair loss, follicles gradually shrink under the influence of DHT. Dutasteride blocks both type 1 and type 2 5-alpha reductase — reducing the conversion of testosterone into DHT more comprehensively than finasteride. At 0.1%, the concentration reflects a clinical judgment that this mid-range strength is right for the individual. Think of dutasteride as taking the foot off the brake — suppressing DHT production across both enzymatic pathways, reducing the hormonal pressure that drives follicle miniaturisation over time.

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Minoxidil: stimulating the follicle

Minoxidil is a potassium channel opener and vasodilator. Applied topically, it improves blood flow to follicles, prolongs the growth phase of the hair cycle, and stimulates follicle cells to produce thicker, healthier hair. It works through an entirely different mechanism from dutasteride — addressing the circulatory and follicle-stimulating side of the equation rather than the hormonal side. Think of minoxidil as waking up the follicles — improving the conditions at the scalp so that existing follicles can produce more and healthier hair.

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How does the Dutasteride 0.1%, Minoxidil 5% in Trichosol solution work?

Pattern hair loss is driven by multiple overlapping processes. This formula targets two of the most important directly.

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Dutasteride: blocking the hormonal signal more completely

In pattern hair loss, follicles gradually shrink under the influence of DHT. Dutasteride blocks both type 1 and type 2 5-alpha reductase — reducing the conversion of testosterone into DHT more comprehensively than finasteride. At 0.1%, the concentration reflects a clinical judgment that this mid-range strength is right for the individual. Think of dutasteride as taking the foot off the brake — suppressing DHT production across both enzymatic pathways, reducing the hormonal pressure that drives follicle miniaturisation over time.

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Minoxidil: stimulating the follicle

Minoxidil is a potassium channel opener and vasodilator. Applied topically, it improves blood flow to follicles, prolongs the growth phase of the hair cycle, and stimulates follicle cells to produce thicker, healthier hair. It works through an entirely different mechanism from dutasteride — addressing the circulatory and follicle-stimulating side of the equation rather than the hormonal side. Think of minoxidil as waking up the follicles — improving the conditions at the scalp so that existing follicles can produce more and healthier hair.

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Dutasteride 0.1%, Minoxidil 5% in Trichosol — Warnings and precautions

Who should not use this product

This product is not suitable for everyone. Extra care is needed if you are pregnant, trying to become pregnant, breastfeeding, have a scalp condition affecting absorption, or have a history of allergy to any ingredient in the formulation.

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Dutasteride warnings

Dutasteride affects hormone pathways. Women who are pregnant or may become pregnant must not use this product — it can affect male foetal development. Men with a history of prostate cancer, BPH, or elevated PSA levels need careful assessment before starting. Dutasteride lowers PSA levels, which may mask early prostate cancer. Baseline PSA screening may be required. The prescriber will discuss these risks during consultation.

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Minoxidil warnings

Minoxidil is a vasodilator. Patients with a history of cardiovascular disease, low blood pressure, or cardiac conditions need careful assessment before starting. Systemic absorption is lower with topical use than oral minoxidil, but cardiovascular status will still be reviewed.

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A note on concurrent treatments

If you are using other topical hair loss agents alongside this solution, disclose this during consultation. Concurrent use of multiple topical hair loss agents is not usually recommended without prescriber guidance.

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Compounded does not mean casual

The Trichosol base and two-ingredient formula do not reduce the need for proper prescribing review. The same thorough safety and suitability checks apply here as with any other prescription treatment. A full medical history — including cardiovascular status, prostate health, pregnancy status, previous medication reactions, and liver function where relevant — will be reviewed during consultation.

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Dutasteride 0.1%, Minoxidil 5% in Trichosol — Side effects

Common side effects

Common side effects may include scalp irritation, dryness, redness, itching, flaking, or temporary shedding early in treatment. The Trichosol base reduces the likelihood of alcohol and propylene glycol-related dryness and stinging, but it does not eliminate the possibility of local reactions entirely. Early shedding is common when starting minoxidil — it occurs as follicles shift through the hair cycle and usually settles within a few months.

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Dutasteride-related effects

Dutasteride at 0.1% topical strength may cause sexual dysfunction in some patients — including reduced libido, erectile dysfunction, or ejaculation disorders. These effects are uncommon with topical application but have been reported. Mood changes, depression, or anxiety have also been documented. The prescriber will discuss this during consultation. Report mood changes, persistent sexual dysfunction, or any other concerning symptoms promptly.

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Minoxidil-related effects

Topical minoxidil may cause unwanted facial hair growth if the product spreads beyond the scalp. Apply only to the scalp and avoid contact with the face. Systemic effects are uncommon with topical use but can include dizziness, palpitations, fluid retention, or low blood pressure.

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When to seek advice

Seek advice if you develop chest pain, dizziness, palpitations, swelling, marked irritation, signs of allergy, severe mood changes, persistent sexual dysfunction, or unwanted hair growth in areas other than the scalp.

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Dutasteride 0.1%, Minoxidil 5% in Trichosol — Side effects

Common side effects

Common side effects may include scalp irritation, dryness, redness, itching, flaking, or temporary shedding early in treatment. The Trichosol base reduces the likelihood of alcohol and propylene glycol-related dryness and stinging, but it does not eliminate the possibility of local reactions entirely. Early shedding is common when starting minoxidil — it occurs as follicles shift through the hair cycle and usually settles within a few months.

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Dutasteride-related effects

Dutasteride at 0.1% topical strength may cause sexual dysfunction in some patients — including reduced libido, erectile dysfunction, or ejaculation disorders. These effects are uncommon with topical application but have been reported. Mood changes, depression, or anxiety have also been documented. The prescriber will discuss this during consultation. Report mood changes, persistent sexual dysfunction, or any other concerning symptoms promptly.

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Minoxidil-related effects

Topical minoxidil may cause unwanted facial hair growth if the product spreads beyond the scalp. Apply only to the scalp and avoid contact with the face. Systemic effects are uncommon with topical use but can include dizziness, palpitations, fluid retention, or low blood pressure.

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When to seek advice

Seek advice if you develop chest pain, dizziness, palpitations, swelling, marked irritation, signs of allergy, severe mood changes, persistent sexual dysfunction, or unwanted hair growth in areas other than the scalp.

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Dutasteride 0.1%, Minoxidil 5% in Trichosol — FAQs

How long does it take to see results?

Hair loss treatment needs patience. Most people need several months of consistent use before visible improvement becomes apparent. Early shedding in the first few weeks is common with minoxidil and is not a sign that treatment is failing. The Trichosol base makes consistent nightly application more comfortable — and comfort supports the consistency that treatment outcomes depend on.

Is this suitable for both men and women?

It may suit some adults, but the prescriber will assess this carefully. Women who are pregnant or trying to become pregnant must not use this product — it contains dutasteride, which is contraindicated in pregnancy. Suitability is always assessed individually.

Why does this formula contain two ingredients rather than three?

Some patients need dutasteride and minoxidil together without tretinoin at this stage — whether because the prescriber wants to assess response to this combination before expanding the formula, or because clinical judgment indicates that two ingredients are the most appropriate approach. If tretinoin or other additions are indicated over time, the formula can be adjusted.

Why is the dutasteride concentration 0.1%?

0.1% is a mid-range compounded dutasteride concentration. The prescriber selects it when clinical assessment — and where used, TrichoTest results — indicates a moderate to strong anti-androgen requirement. It is not a default. It is the appropriate concentration for the individual being treated.

Why is this formula in Trichosol?

Standard topical solutions contain alcohol and propylene glycol — both of which can cause stinging, dryness, and scalp irritation. Trichosol removes both entirely. For patients who have experienced these reactions with standard products, it can make daily treatment significantly more comfortable — and comfort drives the consistency that good outcomes depend on.

How is dutasteride different from finasteride?

Both are 5-alpha reductase inhibitors that reduce DHT. Finasteride selectively blocks type 2 5-alpha reductase. Dutasteride blocks both type 1 and type 2, producing a more comprehensive reduction in DHT. TrichoTest can help identify which is the more appropriate anti-androgen for the individual's genetic profile. The prescriber will discuss the most suitable option.

Can tretinoin be added to this formula later?

Yes. One of the advantages of compounded treatment is that the formula can evolve over time. If clinical assessment or TrichoTest results indicate that tretinoin or other ingredients would add meaningful benefit, the prescriber can adjust the formula accordingly. Discuss this during your consultation or at review.

What is compounding and why does it matter?

Compounding is the preparation of a medicine to order for an individual patient by a licensed pharmacy. This specific two-ingredient combination at 0.1% dutasteride in a Trichosol base does not exist in any standard licensed product — compounding is what makes it possible.

Can I use it if standard hair loss products have irritated my scalp?

Quite possibly. The absence of propylene glycol and alcohol removes two of the most common causes of scalp irritation. Suitability still needs to be assessed by a prescriber, but for patients with reactive scalps this Trichosol formulation is often a more comfortable and sustainable option.

How can TrichoTest help with this treatment?

TrichoTest analyses 26 genetic markers across nine key pathways. It helps the prescriber identify whether dutasteride is the most appropriate anti-androgen, whether 0.1% is the right concentration for the individual's anti-androgen metabolism profile, and whether minoxidil response is likely to be strong via the SULT1A1 pathway — all before treatment begins.

Does TrichoTest guarantee the right treatment?

No. It reduces guesswork and supports more informed prescribing, but it does not guarantee results. Genetic testing works best alongside clinical assessment and your personal treatment history.

Will I need a prescription?

Yes. This is a Prescription Only Medicine. A UK-qualified prescriber must review suitability before supply. The consultation can be completed online at courierpharmacy.co.uk.

Can I stop if I see improvement?

Do not stop or change treatment without advice. Hair loss often returns to its previous pattern if treatment stops, even when results have been encouraging.

What is the Gro hair loss range?

Gro is the compounded hair loss brand from Courier Pharmacy and Medical Mojo. It offers liquid, foam, and Trichosol formulations, all priced at £29.99 for up to three active ingredients — less than £1 per day.

How much does this cost?

£29.99 for a 30ml bottle, designed to last around one month. Less than £1 per day.

How long does a 30ml bottle last?

Around one month when applied as directed — 1ml applied to the scalp at night using the dropper bottle.

What is the difference between liquid, foam, and Trichosol?

Liquid is a traditional spray solution containing alcohol and propylene glycol. Foam is lighter, faster-drying, and easier to apply without dripping. Trichosol is a propylene glycol free and alcohol free option for patients with sensitive or reactive scalps. All are available across the Gro range.

Is Trichosol better than liquid or foam for this formula?

It depends on your scalp and your previous experience with topical treatments. Trichosol is often the most appropriate choice for patients who have reacted to standard bases or who want a more comfortable daily experience. The prescriber can help you decide.

Can I use other hair loss products at the same time?

Concurrent use of multiple topical hair loss agents is not usually recommended without prescriber guidance. Disclose all current treatments during consultation.

I have a heart condition — can I use topical minoxidil?

Disclose any cardiovascular history during consultation. The prescriber will assess suitability carefully. Topical minoxidil carries lower systemic absorption than oral forms, but cardiovascular status is always reviewed before prescribing.

What if I have had problems with dutasteride or finasteride before?

Disclose this during consultation. Any previous adverse effects from either anti-androgen are essential information for the prescriber to assess your suitability safely.

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Disclaimer

This article is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any new treatment.

References

[1] NHS. Hair loss. Available at: https://www.nhs.uk/conditions/hair-loss/

[2] NICE CKS. Alopecia — androgenetic. Available at: https://cks.nice.org.uk/topics/alopecia-androgenetic/

[3] Suchonwanit, P., Thammarucha, S. and Leerunyakul, K. (2019) Minoxidil and its use in hair disorders: a review. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6691938/

[4] Courier Pharmacy (n.d.) Dutasteride and minoxidil: a powerful combination for hair loss in the UK. Available at: https://courierpharmacy.co.uk/dutasteride-and-minoxidil-a-powerful-combination-for-hair-loss-in-the-uk/

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Byline

Written by the Courier Pharmacy clinical content team and reviewed in line with UK pharmacy standards.

How this content was created

This content was created using UK clinical guidance, peer-reviewed evidence, and patient-focused healthcare writing principles. It supports safe understanding, not self-prescribing, and has been reviewed in line with pharmacy standards.

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Gro Dutasteride 0.1%, minoxidil 5% in Trichosol topical hair loss solution courierpharmacy.co.uk
Dutasteride 0.1%, minoxidil 5% in Trichosol topical hair loss solution
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