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Etoricoxib 90mg tablets

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Short description Etoricoxib 90mg Tablets

Etoricoxib 90mg Tablets are a once-daily, prescription-only COX-2 selective anti-inflammatory used for the symptomatic relief of rheumatoid arthritis, ankylosing spondylitis, and short-term postoperative dental pain in adults. Prescribed and dispensed in the UK by Courier Pharmacy with a personalised online consultation, GPhC-registered pharmacist oversight, and discreet home delivery.

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Description

Product description Etoricoxib 90mg Tablets

Etoricoxib 90mg Tablets are a prescription-only anti-inflammatory medicine licensed in the UK. Doctors use it for the symptomatic relief of rheumatoid arthritis (RA), ankylosing spondylitis, and short-term postoperative dental pain in adults aged 16 years and over.
Each film-coated tablet contains 90mg of etoricoxib. Etoricoxib is a selective COX-2 inhibitor, which means it targets inflammation in a more focused way than some traditional NSAIDs. The tablets come in packs of 28, so the pack usually lasts four weeks at the standard once-daily dose. As a result, it’s easy to build into a wider rheumatology plan.
If you’ve tried NSAIDs, paracetamol, or short appointments that never quite solve the problem, you’re not alone. However, Etoricoxib 90mg won’t suit everyone, and it isn’t always the first choice. Still, for some adults with inflammatory arthritis who need stronger anti-inflammatory cover than 60mg provides, it can make a real difference. Either way, our job is to help you decide if it fits, not to rush you.

Key features and specifications

  • Active ingredient: Etoricoxib 90mg
  • Form: Film-coated oral tablets
  • Pack size: 28 tablets (usually a one-month supply at standard dose)
  • Medicine class: COX-2 selective non-steroidal anti-inflammatory drug (NSAID)
  • Licensed UK indications at 90mg: Rheumatoid arthritis, ankylosing spondylitis, short-term postoperative dental pain (max 3 days)
  • Prescription status: POM (Prescription Only Medicine)
  • Dispensed by: Courier Pharmacy (UK GPhC-registered pharmacy)

Additional information

Quantity

1 x 28, 2 x 28, 3 x 28

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

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Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Safdar Ali
BSc Pharmacy

Pharmacist


Etoricoxib 90mg Tablets

Inflammatory arthritis has a way of stealing the small things. Doing up a button. Climbing the stairs without thinking. Sleeping a full night without your spine staging a protest. Etoricoxib 90mg tablets, a prescription COX-2 selective anti-inflammatory, can ease enough of that inflammation to give those small things back. At Courier Pharmacy, we believe pain relief should fit the person sitting with it, whether that’s someone living with rheumatoid arthritis, ankylosing spondylitis, or the cumulative weight of chronic inflammatory illness. You’re not broken. The immune signalling driving your joints is overheated. Here’s how this tablet works, who it suits, and how we’ll help you decide if it belongs in your treatment plan.

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Five key takeaways

  • Etoricoxib 90mg tablets are a prescription-only COX-2 selective NSAID licensed in the UK for the symptomatic relief of rheumatoid arthritis and ankylosing spondylitis, and for short-term postoperative dental pain.
  • Current MHRA guidance recommends starting at 60mg once daily for RA and ankylosing spondylitis, with 90mg used only when 60mg gives insufficient relief; down-titration is encouraged once symptoms stabilise.
  • Etoricoxib selectively targets the COX-2 enzyme, providing meaningful anti-inflammatory action with less impact on the stomach-protective COX-1 pathway than traditional NSAIDs.
  • Cardiovascular, renal and blood-pressure risks rise with dose and duration, so prescriber assessment and regular review are essential.
  • At Courier Pharmacy, every Etoricoxib 90mg prescription is reviewed by a UK prescriber and dispensed by a GPhC-registered pharmacist, with personalised follow-up and free community clinics in Derby.

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Treatment dosage Etoricoxib 90mg Tablets

For adults with rheumatoid arthritis or ankylosing spondylitis, current MHRA guidance recommends starting at 60mg once daily. If 60mg doesn’t bring sufficient relief, the dose may be increased to 90mg once daily, which is the maximum licensed daily dose for these indications. Once your condition is clinically stabilised, down-titration back to 60mg once daily may be appropriate. The tablet is swallowed whole with water and can be taken with or without food. On an empty stomach the onset of effect may be a little faster, which some people prefer for morning stiffness.

For postoperative dental pain, the recommended dose is 90mg once daily, limited to a maximum of 3 days. Some patients may need additional postoperative analgesia during that short window, which your dentist or prescriber will coordinate.

Older adults don’t usually need a dose change based on age alone, although prescribers tend to be more cautious about cardiovascular and renal monitoring. People with mild liver impairment should not exceed 60mg daily, which means 90mg isn’t appropriate for them. Moderate liver impairment caps the dose at 30mg once daily. Etoricoxib is contraindicated in severe liver impairment and in anyone with a creatinine clearance below 30 ml/min, which is why your prescriber will ask about kidney and liver history during your consultation.

Overview of Etoricoxib 90mg

The guiding principle, echoed throughout NICE and BNF guidance and reinforced by the 2016 MHRA Drug Safety Update on etoricoxib, is to use the lowest effective dose for the shortest time necessary to control symptoms. Etoricoxib is not licensed for under-16s, and the need for ongoing treatment should be reassessed regularly rather than left on autopilot. We’ll always check in with you, not just at the point of prescribing, but as your condition evolves.

Inflammatory arthritis isn’t simple wear and tear. Conditions like rheumatoid arthritis and ankylosing spondylitis are driven by immune-mediated inflammation, where the body’s own signalling pathways turn against joints, tendons, and in the case of ankylosing spondylitis, the spine. Etoricoxib 90mg targets one part of that picture, the inflammatory prostaglandin pathway, and does so more selectively than older NSAIDs like ibuprofen or naproxen.

The etoricoxib 90mg dose

The 90mg strength is the upper end of the licensed dosing range for RA and ankylosing spondylitis, used when 60mg isn’t quite enough. The MHRA’s clear message since 2016 is that this dose should be used judiciously and reviewed regularly. That matches how we work. A medicine that’s helping should keep helping; one that isn’t earning its place deserves to be re-evaluated, not refilled by default.

It’s worth saying clearly: COX-2 inhibitors are not safer in every way than traditional NSAIDs. They reduce certain gastrointestinal risks but do not eliminate them, and they carry their own cardiovascular profile. The European Medicines Agency and MHRA have both been explicit that the benefit-to-risk balance at 90mg is acceptable for RA and ankylosing spondylitis in carefully selected patients, but the assessment matters.

Many of our patients arrive after years of being told their pain is exaggerated or that they should just exercise more. We don’t subscribe to that framing. Inflammatory arthritis is a real, measurable, immune-driven process, and treating it effectively is the first step toward keeping the wider life you want. Whether you’re managing RA, ankylosing spondylitis, fibromyalgia overlap, or a more complex chronic pain pattern, the goal is to find a regimen that respects your body’s signals rather than overriding them.

The bigger picture for inflammatory arthritis almost always involves more than NSAIDs. Disease-modifying treatments like methotrexate or biologics under rheumatology supervision, physiotherapy, sustainable movement, sleep, stress regulation, and connection all matter. Tablets are one tool in a wider toolkit. Our community work in Derby is one way we try to live up to that, but the spirit of it travels with every prescription we send out.

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Why choose Courier Pharmacy for Etoricoxib 90mg Tablets

We started Courier Pharmacy because too many people were being handed prescriptions like takeaway flyers, with no conversation, no follow-up, and no sense that anyone had actually listened. Personalisation means looking at your blood pressure history, your kidney function, your other medicines and your wider rheumatology picture, then deciding together whether etoricoxib 90mg fits, and at what point down-titration to 60mg might be appropriate. It doesn’t mean clicking through a tickbox form and waiting for the parcel.

Guidance carries through after the prescription is issued. Our GPhC-registered pharmacists are reachable, not just for emergencies but for the smaller questions that often go unasked: should I keep taking this if I’m starting a new biologic? Is this headache the tablet or the flare? Can I cut down for a few weeks and see how I feel? You can ask. We’ll answer. Our medical lead, the figure behind much of our clinical thinking, is Dr Ada Jex-Cori, an evidence-led, community-rooted clinician who built her practice on the belief that people in chronic pain deserve to be heard before they’re prescribed.

Trust is the part that has to be earned, not claimed. We’re a UK-regulated pharmacy, we publish our processes, we tell you when something isn’t suitable, and we’d rather lose a sale than place a medicine where it doesn’t belong. Whether you’re navigating rheumatoid arthritis, ankylosing spondylitis, fibromyalgia support, MCAS care, or chronic fatigue care that fits your life, we’ll meet you where you are, not where the system wishes you were.

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Buy Etoricoxib 90mg Tablets (Prescription Only) from Courier Pharmacy

Etoricoxib 90mg Tablets are a Prescription Only Medicine (POM). That means you cannot buy them over the counter, and we cannot dispense them without a prescriber’s assessment. This isn’t bureaucracy; it’s the protection that stands between you and a cardiovascular event you didn’t know was coming. Here’s how the process works at Courier Pharmacy:

  • Complete a quick online consultation
  • A UK prescriber reviews your answers
  • If approved, a prescription is issued
  • We dispense and deliver discreetly to your door

If it isn’t suitable for you, we’ll explain why and suggest the next best option. Sometimes that’s a different medicine, sometimes a non-drug approach, sometimes a referral. We also run free fortnightly drop-in clinics and talks at Insomnia, Derby, 12 to 1pm, where you can sit down with a member of our team in person and ask anything you like. No appointment, no cost, no obligation.

 

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Summary

  • A prescription-only COX-2 selective NSAID, licensed at 90mg for rheumatoid arthritis, ankylosing spondylitis, and short-term postoperative dental pain
  • Works by reducing inflammation-driving prostaglandins, easing joint pain, stiffness and spine inflammation
  • Carries cardiovascular, blood pressure and renal considerations that rise with dose and duration, so prescriber assessment is essential
  • Best paired with a wider rheumatology plan, including DMARDs, physiotherapy, exercise and pacing where appropriate
  • Available from Courier Pharmacy with full prescriber review, GPhC-registered pharmacist oversight, and follow-up

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Active ingredient in Etoricoxib 90mg Tablets

The active ingredient is etoricoxib, a selective inhibitor of cyclooxygenase-2 (COX-2). COX-2 is one of two enzymes that produce prostaglandins, the chemical signals that drive inflammation, pain and fever. By targeting COX-2 while largely sparing COX-1, etoricoxib reduces inflammatory pain without the same impact on the stomach-protective prostaglandins or on platelet function that older non-selective NSAIDs cause.

Each tablet also contains pharmaceutical excipients used in the film-coat and tablet core. If you have known intolerances or are managing conditions like mast cell activation syndrome (MCAS) where excipients matter, ask us during your consultation. We'll review the full ingredient list with you and, where appropriate, discuss whether a compounded alternative might suit you better.

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What is Etoricoxib 90mg Tablets for?

At the 90mg strength, Etoricoxib is licensed in the UK for the symptomatic relief of rheumatoid arthritis and ankylosing spondylitis in adults, and for the short-term treatment of moderate postoperative dental pain. In rheumatoid arthritis, it eases the joint pain, stiffness and inflammation that characterise active disease. In ankylosing spondylitis, it targets the spine pain, morning stiffness and reduced mobility that can dominate someone's day.

Lower strengths of etoricoxib (30mg, 60mg) are licensed for osteoarthritis, and the highest strength (120mg) is licensed for acute gout flares. The 90mg tablet is the dose used when inflammatory arthritis symptoms aren't adequately controlled at 60mg, or for a short three-day course of postoperative dental pain relief.

A note on chronic illness contexts. People living with fibromyalgia, CFS/ME or MCAS sometimes ask whether a stronger NSAID will help. The honest answer is: it depends on whether inflammation is a meaningful driver of your specific pain pattern. For people with an inflammatory arthritis overlay, etoricoxib 90mg can be useful. For pain patterns dominated by central nervous system sensitisation rather than peripheral inflammation, it often does little. That's exactly the kind of conversation we want to have with you rather than leaving you to guess.

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How does Etoricoxib 90mg Tablets work?

Pain and inflammation are coordinated by tiny chemical messengers called prostaglandins. When immune cells are activated against joint tissues in conditions like rheumatoid arthritis or ankylosing spondylitis, the COX-2 enzyme ramps up prostaglandin production, which sensitises nerves, dilates local blood vessels and recruits more immune cells. The result is the familiar bundle of swelling, heat, stiffness and pain. Etoricoxib slots into the active site of COX-2 and blocks it, so the inflammatory signal is dialled down at the source.

What sets COX-2 selective inhibitors apart from older NSAIDs is what they leave alone. COX-1, the sister enzyme, makes prostaglandins that help maintain the stomach lining and support normal platelet function. Traditional NSAIDs like ibuprofen, naproxen and diclofenac inhibit both COX-1 and COX-2, which is part of why long-term use carries a meaningful risk of gastric irritation and bleeding. Etoricoxib's preferential action on COX-2 means it tends to be gentler on the stomach lining, although it does not eliminate gastrointestinal risk entirely.

Clinical trials in ankylosing spondylitis have shown pain relief observable as early as four hours after the first dose, with significant improvements in spine pain, inflammation, stiffness and function over the treatment period. In rheumatoid arthritis, etoricoxib 90mg once daily has demonstrated meaningful improvements in pain, inflammation and mobility, with effects maintained over 12-week studies. That matters because inflammatory arthritis is rarely a short-term problem; it needs a medicine that keeps working without losing effect.

After you swallow the tablet, etoricoxib is absorbed from the gut, reaches peak blood levels within roughly one hour on an empty stomach, and has a half-life of around 22 hours. That long half-life is why once-daily dosing works. Steady-state concentrations are reached within a few days of regular use, which is also when people typically start to feel the most consistent benefit.

The trade-off worth understanding is cardiovascular. Because COX-2 inhibitors don't reduce platelet aggregation in the way non-selective NSAIDs do, they don't provide the small anti-clotting effect that some older drugs offer. Combined with prostaglandin pathway effects on blood pressure and the kidneys, this is why the MHRA advises careful cardiovascular risk assessment before prescribing any COX-2 inhibitor, and why the 90mg dose for RA and ankylosing spondylitis is reserved for people whose symptoms aren't controlled at 60mg.

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How to use Etoricoxib 90mg Tablets

Take one 90mg tablet by mouth once a day, swallowed whole with water. You can take it with or without food, but on an empty stomach the onset of effect may be a little faster, which some people find useful for morning joint stiffness. Try to take it at roughly the same time each day. Routine helps, both for memory and for steady blood levels.

Don't increase the dose on your own initiative if a tablet doesn't feel like enough on a bad day. The 90mg dose is already the maximum licensed daily dose for RA and ankylosing spondylitis. Doubling up brings risk without proportional benefit. If your symptoms aren't being managed, get in touch with us. Sometimes the answer is a referral to rheumatology for review of disease-modifying treatment; sometimes it's adding a non-drug strategy like targeted physiotherapy or a topical option. The decision belongs with a clinician who knows your context.

Practical tips from our pharmacists: keep the pack visible (kitchen counter, not bathroom cabinet); pair the dose with an existing habit like morning coffee or brushing your teeth; if you miss a dose, take it as soon as you remember unless it's nearly time for the next one, in which case skip the missed dose. Never double up to catch up. Store at room temperature, away from direct sunlight, and out of reach of children.

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Warnings and precautions for Etoricoxib 90mg Tablets

Etoricoxib is not suitable for everyone, and the list of cautions matters more at the 90mg strength than at lower doses. It is contraindicated in active peptic ulceration or active gastrointestinal bleeding, severe heart failure, established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease, uncontrolled hypertension where blood pressure persistently sits above 140/90 mmHg, severe liver impairment and severe kidney impairment (creatinine clearance below 30 ml/min). It is also not recommended during pregnancy or while trying to conceive.

Blood pressure deserves special attention. Etoricoxib can raise blood pressure, and the risk increases with dose. NICE and the MHRA recommend that blood pressure is checked before starting and monitored within two weeks of starting, then periodically thereafter. If you have a home blood pressure monitor, share readings with us. If you don't, we can talk you through a simple checking routine and arrange in-pharmacy checks at our Derby clinic.

Cardiovascular risk factors deserve specific consideration at the 90mg dose. People with diabetes, high cholesterol, smoking history, family history of early heart disease or established cardiovascular disease should only take etoricoxib after a careful weighing of benefits and risks. The MHRA's 2016 Drug Safety Update reinforced that the cardiovascular risks of etoricoxib increase with dose and duration of exposure, and recommended down-titration once symptoms stabilise. Tell your prescriber about every medication and supplement you take, including herbal products, and any history of stomach ulcers, asthma, or allergic reactions to NSAIDs or aspirin.

Rare but serious skin reactions, including Stevens-Johnson syndrome and toxic epidermal necrolysis, have been reported with etoricoxib. These usually appear in the first month of treatment. If you develop a new rash, blistering, peeling, or mucosal involvement (eyes, mouth, genitals), stop the tablet and seek urgent medical attention. The same applies to symptoms of liver problems, including yellowing of the skin or eyes, dark urine, or persistent nausea.

If you become pregnant while taking etoricoxib, or are planning a pregnancy, contact us. The medicine is not recommended in pregnancy, particularly in the third trimester. Breastfeeding caution applies because excretion in human milk hasn't been fully characterised.

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Side effects of Etoricoxib 90mg Tablets

Most people taking etoricoxib 90mg tolerate it well, although side effects tend to be slightly more common at higher doses than at lower ones. Common side effects, occurring in up to one in ten people, include headache, dizziness, palpitations, raised blood pressure, indigestion, abdominal discomfort, nausea, fluid retention (ankle or leg swelling), and feeling generally fatigued or flu-like. Many of these settle within the first couple of weeks. Tell us early if they don't.

Less common effects, occurring in fewer than one in a hundred, include sleep disturbance, mood changes, blurred vision, taste changes, tinnitus, mouth ulcers, constipation, diarrhoea, muscle cramps, raised liver enzymes on blood tests, and changes in kidney function. Rarer effects include serious gastrointestinal events such as ulcer or bleeding, severe skin reactions, hepatitis, kidney failure, and hypersensitivity reactions including angioedema.

Cardiovascular events, including heart attack, stroke and worsening heart failure, are recognised risks of all NSAIDs, including COX-2 selective inhibitors. The absolute risk for any individual depends heavily on baseline cardiovascular risk, dose and duration, and is one of the key reasons the MHRA recommends regular reassessment for anyone on long-term etoricoxib 90mg.

If something feels wrong, trust that signal. Stop the tablet if you experience symptoms suggesting a serious reaction (chest pain, shortness of breath, sudden weakness or speech difficulty, severe rash, severe abdominal pain, vomiting blood, black stools, swelling of the face or throat) and seek emergency medical attention.

Suspected side effects can and should be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Reporting helps build the safety picture for everyone. We can help you complete a Yellow Card report if you'd like a hand.

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Drug interactions with Etoricoxib 90mg Tablets

Etoricoxib interacts with a range of medicines, and the interactions are worth taking seriously, particularly during long-term treatment for inflammatory arthritis. Warfarin and other oral anticoagulants need close INR monitoring when etoricoxib is introduced or stopped, because etoricoxib can raise INR and the bleeding risk that goes with it. Direct oral anticoagulants like rivaroxaban, apixaban, edoxaban and dabigatran are not formally restricted, but combined bleeding risk should be weighed up by a clinician.

Blood pressure medicines, including ACE inhibitors (such as ramipril, lisinopril), angiotensin II receptor blockers (such as losartan, candesartan) and diuretics, can have their effect blunted by etoricoxib. The combination also raises the risk of acute kidney injury, particularly in older adults or those who become dehydrated. If you take any of these, expect more frequent blood pressure and kidney function monitoring.

Other NSAIDs, including over-the-counter ibuprofen and aspirin at anti-inflammatory doses, should not be combined with etoricoxib because the gastrointestinal risk compounds without much extra benefit. Low-dose aspirin used for cardiovascular protection is a different question and is usually allowed, but discuss it with your prescriber. Methotrexate, commonly used in rheumatoid arthritis, can have raised levels on co-administration with etoricoxib, so people on methotrexate need careful supervision; this combination is often appropriate but always under shared care.

Hormonal contraception, lithium, ciclosporin, tacrolimus, rifampicin and some antifungals can also interact with etoricoxib in clinically meaningful ways. People taking biologic therapies for inflammatory arthritis should let us know during the consultation, as combination therapy is often appropriate but needs sensible co-ordination. Always give a full medicines history during your consultation, including supplements, herbal products and recreational substances. Honesty here is genuinely safer than discretion.

Alcohol doesn't directly interact pharmacokinetically with etoricoxib, but heavy or regular drinking adds to stomach, liver and cardiovascular risks. Moderation matters more on long-term NSAIDs than off them.

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Frequently asked questions about Etoricoxib 90mg Tablets

Is Etoricoxib 90mg Tablets an opioid?

No. Etoricoxib is a non-steroidal anti-inflammatory drug (NSAID), specifically a selective COX-2 inhibitor. It works on inflammation-driving prostaglandins, not on opioid receptors. It isn't addictive in the way opioids are, doesn't cause respiratory depression, and isn't a controlled drug. That said, it isn't risk-free, which is why it remains prescription-only.

How quickly does Etoricoxib 90mg start working?

Many people notice some pain relief within one to two hours of the first dose, particularly when taken without food. In ankylosing spondylitis trials, pain relief was observed as early as four hours after the first dose. The full anti-inflammatory effect builds over several days of regular dosing as steady-state concentrations are reached.

Why does the MHRA recommend starting at 60mg rather than 90mg?

The MHRA's 2016 Drug Safety Update reinforced that cardiovascular and other risks of etoricoxib rise with dose and duration. For rheumatoid arthritis and ankylosing spondylitis, starting at 60mg keeps risk lower for those who respond at that dose. 90mg is reserved for people whose symptoms aren't adequately controlled at 60mg, with down-titration once stable.

Can I take Etoricoxib 90mg with paracetamol?

In most cases, yes. Paracetamol works on a different pathway and is often combined with NSAIDs for layered pain relief. Stick to standard paracetamol dosing (no more than 4g per 24 hours in adults) and let us know during your consultation if you're already taking paracetamol-containing combination products.

Can I take ibuprofen at the same time?

No. Combining etoricoxib with another NSAID like ibuprofen, naproxen or aspirin at anti-inflammatory doses significantly increases the risk of stomach ulcers, bleeding and kidney problems without adding meaningful benefit. Low-dose cardiac aspirin (75mg) is a different conversation, and your prescriber will guide you.

Can I take Etoricoxib 90mg with methotrexate?

Often yes, but with supervision. Etoricoxib can raise methotrexate levels, so people on methotrexate for rheumatoid arthritis need careful monitoring of blood counts and kidney function. This combination is regularly used in rheumatology under shared care, but it should always be coordinated between your rheumatology team and our pharmacists.

Does Etoricoxib 90mg raise blood pressure?

It can. Etoricoxib affects renal prostaglandins involved in sodium balance and vascular tone, and the risk rises with dose. The MHRA recommends blood pressure monitoring before starting and within two weeks of starting, then periodically thereafter. People with uncontrolled hypertension should not take etoricoxib 90mg.

Can I drink alcohol while taking Etoricoxib 90mg?

There is no direct pharmacokinetic interaction, but alcohol increases the risk of stomach irritation, liver stress and cardiovascular complications. NICE guidance generally favours moderation while on any NSAID, particularly long-term. If you drink regularly or heavily, let us know during your consultation.

Can I drive while taking Etoricoxib 90mg?

For most people, yes. A minority experience dizziness, drowsiness or blurred vision, particularly during the first few days. If you notice any of these, don't drive or operate machinery until they settle, and contact us for advice. The DVLA does not list etoricoxib as a notifiable medication for driving.

Is Etoricoxib 90mg safe long-term?

Long-term use is possible for some people with rheumatoid arthritis or ankylosing spondylitis, but requires regular review. The MHRA recommends reassessing the need for ongoing treatment and considering down-titration to 60mg once symptoms stabilise. Annual checks of blood pressure, kidney function, liver function and cardiovascular risk are sensible.

What's the difference between Etoricoxib 90mg and naproxen?

Naproxen inhibits both COX-1 and COX-2, while etoricoxib selectively inhibits COX-2. That selectivity tends to make etoricoxib gentler on the stomach but doesn't reduce cardiovascular risk in the same way. Naproxen is generally considered to have a more favourable cardiovascular profile than other NSAIDs, which is why some rheumatologists prefer it for long-term use.

Does Etoricoxib 90mg work for ankylosing spondylitis?

Yes. Clinical trials show etoricoxib 90mg once daily significantly improves spine pain, inflammation, stiffness and function in ankylosing spondylitis, with pain relief observable as early as four hours after the first dose. It is one of several NSAID options for symptom control alongside physiotherapy and, where appropriate, biologic therapy.

Can I take Etoricoxib 90mg if I have asthma?

People with NSAID-sensitive asthma or aspirin-exacerbated respiratory disease should generally avoid all NSAIDs, including COX-2 selective ones, unless a specialist has assessed and approved use. Tell your prescriber if you've ever had asthma worsen after taking ibuprofen, aspirin or any other NSAID.

Does Etoricoxib 90mg help with fibromyalgia?

Etoricoxib is not licensed for fibromyalgia, and the evidence base is mixed because central nervous system sensitisation, not classical inflammation, drives much of fibromyalgia pain. Some people with overlapping inflammatory conditions do benefit. We'll explore your specific pain pattern during the consultation and only prescribe where there's a clear rationale.

What should I do if I miss a dose?

Take the missed dose as soon as you remember unless it's nearly time for the next one. In that case, skip the missed dose and continue with your regular schedule. Don't take a double dose to make up. Missing the occasional dose is rarely a clinical issue.

Can I take Etoricoxib 90mg with antidepressants?

It depends on the antidepressant. SSRIs (such as sertraline, citalopram, fluoxetine) can increase bleeding risk when combined with NSAIDs, particularly in older adults or those on other antiplatelets. Tell your prescriber about every antidepressant, including those you've recently stopped, so the combined risk can be weighed.

Is Etoricoxib 90mg available on the NHS?

Yes, etoricoxib is available on NHS prescription where clinically appropriate, although prescribing is generally restricted to specific indications and after other options have been considered. If you'd rather avoid waiting lists or your local formulary doesn't routinely list it, a private online consultation is one route to access.

Can people with MCAS take Etoricoxib 90mg?

Some people with MCAS tolerate etoricoxib well; others react to either the active or to excipients in the tablet. We always review the full excipient list during your consultation if you have known mast cell reactivity, and where appropriate we can discuss whether a compounded, simpler formulation is a better fit.

How is Etoricoxib 90mg stored?

Store at room temperature, below 30°C, in the original pack, away from direct sunlight and moisture. Keep out of sight and reach of children. Don't use beyond the expiry date printed on the pack, and return any unused tablets to a pharmacy for safe disposal.

How do I order Etoricoxib 90mg Tablets from Courier Pharmacy?

Complete the short online consultation on our site, and a UK prescriber will review your answers. If etoricoxib 90mg is suitable, a prescription is issued, our GPhC-registered pharmacy dispenses your tablets and delivers them discreetly to your door. If it isn't suitable, we'll tell you why and suggest a next step. You can also drop into our free fortnightly clinic at Insomnia, Derby, to ask in person.

More than a prescription: our community

Healthcare shouldn't only happen when you're paying for it. Every fortnight we run free drop-in talks and clinics at Insomnia, Derby, from 12pm to 1pm. Bring a question, bring a friend, bring a stack of bewildering letters from another clinic; we'll sit with you. We cover inflammatory arthritis, chronic pain, hair loss, men's health, MCAS, fibromyalgia, low-dose naltrexone, and whatever else people bring through the door. No appointment. No cost. No pressure. Learn more about our community talks.

How this content was created

Written by the Courier Pharmacy editorial team and reviewed by a GPhC-registered pharmacist. Grounded in the latest NHS, NICE, BNF and EMC guidance, peer-reviewed studies, and the real questions patients bring to our drop-in clinics in Derby.

Author: The Courier Pharmacy Clinical Editorial Team

Reviewed by: GPhC-registered pharmacist, Courier Pharmacy

Last reviewed: 11 May 2026

References

  1. Milpharm Limited (2026) Etoricoxib 90 mg film-coated tablets: Summary of Product Characteristics (SmPC). Uxbridge: Milpharm Limited. Available at: https://www.medicines.org.uk/emc/product/9317/smpc
  2. Joint Formulary Committee (2026) British National Formulary: Etoricoxib. London: BMJ Group and Pharmaceutical Press. Available at: https://bnf.nice.org.uk/drugs/etoricoxib/

Disclaimer: This article is for information only and isn’t a substitute for personal medical advice, diagnosis, or treatment.

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Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.9317.pdf

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Etoricoxib 90mg tablets
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