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Solpadeine Plus Capsules (24 pack)
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Solpadeine Plus Capsules (24 pack) are a triple-action painkiller combining paracetamol 500mg, codeine phosphate 8mg and caffeine 30mg per capsule, licensed in the UK for the short-term relief of acute moderate pain not relieved by paracetamol or ibuprofen alone.
Supplied in the UK by Courier Pharmacy with pharmacist-led advice and discreet home delivery.
Solpadeine Plus Capsules are red-and-white gelatin capsules containing paracetamol 500mg, codeine phosphate hemihydrate 8mg and caffeine 30mg. The 24-capsule pack is one of the two standard pack sizes (alongside 24). Each capsule combines three actives that work through different mechanisms, giving stronger pain relief than paracetamol alone for moderate pain that hasn’t responded to single-ingredient treatments.
Solpadeine has been a UK pain-relief staple for decades. We dispense it from a UK-registered pharmacy where every order is reviewed by a GPhC-registered pharmacist.
Codeine-containing medicines need a careful approach because of addiction risk and medication-overuse headache, and pharmacist oversight is genuinely useful, not just a regulatory formality. MHRA regulations also limit codeine-containing OTC supply to one pack per order in most cases.
If you’ve been combining paracetamol and ibuprofen and the pain still isn’t shifting, Solpadeine Plus adds two important elements: a low dose of codeine for stronger central analgesia, and caffeine which boosts paracetamol’s analgesic effect.
The capsule format is straightforward to swallow with water and travels well, although the trade-off is that solid capsules are absorbed slightly more slowly than soluble tablets. It’s not the right choice for everyone, particularly anyone with a history of opioid sensitivity, medication-overuse headache, or codeine intolerance.
Key features and specifications:
Active ingredients: paracetamol 500mg + codeine phosphate hemihydrate 8mg + caffeine 30mg per capsule
Form: red-and-white film-sealed gelatin capsules
Pack size: 24 capsules
Indication: short-term treatment of acute moderate pain when paracetamol or ibuprofen alone aren’t enough
Maximum duration: 3 days continuous use without medical advice
Suitable from: adults and adolescents aged 12 and over
Legal status: Pharmacy (P) medicine
Supplied by: Courier Pharmacy, UK GPhC-registered
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Migraine that’s still kicking after the paracetamol’s worn off. Back pain that won’t let you settle. Toothache that’s been brewing all weekend before the dentist’s open. Solpadeine Plus Capsules are one of the UK’s most familiar combination painkillers, pairing paracetamol, codeine and caffeine in a swallow-and-go capsule for moderate pain that hasn’t yielded to single-ingredient options.
The 24-capsule pack gives you a fortnight’s worth at the lower end of the dosing scale, while the codeine content means it’s strictly a short-term treatment. At Courier Pharmacy, we believe pain relief should suit the person, not the marketing budget. Whether you’re managing migraine, period pain, fibromyalgia support, or just a stubborn pain that needs more than paracetamol alone, this page is here to help you decide whether Solpadeine Plus fits your situation.
Five key takeaways
Solpadeine Plus Capsules are a UK Pharmacy (P) combination painkiller containing paracetamol 500mg, codeine phosphate hemihydrate 8mg and caffeine 30mg per capsule.
They’re licensed for the short-term treatment of acute moderate pain not relieved by paracetamol, ibuprofen or aspirin alone, including migraine, headache, period pain, dental pain, backache, sprains, strains and sciatica.
Adults take 2 capsules every 4 to 6 hours as needed, with a maximum of 8 capsules in 24 hours. The 24-capsule pack provides up to four days of treatment at full dose.
Because Solpadeine Plus contains codeine, it must not be used for more than three days continuously without medical advice, due to addiction and medication-overuse headache risks.
Courier Pharmacy supplies Solpadeine Plus with full pharmacist oversight, personalised guidance, and free fortnightly community clinics in Derby.
Overview of Solpadeine Plus Capsules
Combination painkillers exist for a clear reason: moderate pain that hasn’t yielded to one ingredient often does yield to a sensible combination working through different mechanisms. Solpadeine Plus’s pairing of paracetamol with low-dose codeine and a small amount of caffeine targets pain centrally (paracetamol, codeine) while caffeine provides a boost shown in trials to enhance paracetamol’s analgesic effect.
The codeine dose is intentionally low (8mg per capsule, up to 16mg per dose). Compared with prescription opioid analgesics, this is modest, but it still adds meaningful analgesia for many people. It’s also low enough that for most people, codeine-related side effects like constipation and drowsiness are limited unless tablets are taken at the maximum dose or for several days running.
It’s worth being honest about what Solpadeine Plus isn’t. It isn’t a long-term pain management strategy, and it isn’t a treatment for the underlying cause of recurrent pain. Codeine-containing medicines have a clear three-day limit, and codeine itself can drive medication-overuse headache, where the painkiller paradoxically causes more headaches over time. Solpadeine is also one of the most commonly cited products in UK codeine dependence cases, which is part of why pharmacist oversight matters.
Many of our patients arrive after years of cycling through over-the-counter painkillers without a clear plan for what comes next. We don’t subscribe to that framing. Whether you’re managing chronic pain, period pain, fibromyalgia support, MCAS care, or chronic fatigue care that fits your life, the goal is to find a regimen that respects your body’s signals rather than overriding them.
The bigger picture for any persistent pain pattern involves identifying what’s driving it, addressing modifiable factors, and where appropriate, considering prescription options or specialist input. Combination OTC painkillers are a tool, not the whole toolkit. Our community work in Derby is one way we try to live up to that.
Why choose Courier Pharmacy for Solpadeine Plus Capsules
We started Courier Pharmacy because too many people were being handed codeine medicines like takeaway flyers, with no conversation about the bigger picture. Personalisation means looking at your pain pattern, your other medicines, your wider health context, then deciding together whether Solpadeine Plus Capsules fit. For frequent pain, we’ll also flag whether referral for a longer-term plan makes sense.
Guidance carries through after the order goes out. Our GPhC-registered pharmacists are reachable for the smaller questions that often go unasked: am I at risk of medication-overuse headache? Should I be tracking my pain pattern? Is it time to think about prescription options? Our medical lead, the figure behind much of our clinical thinking, is Dr Ada Jex-Cori, an evidence-led, community-rooted clinician who built her practice on the belief that people in pain deserve to be heard before they’re prescribed.
Trust is the part that has to be earned, not claimed. We’re a UK-regulated pharmacy, we publish our processes, we tell you when something isn’t suitable, and we’d rather lose a sale than place a codeine-containing medicine where it doesn’t belong. Whether you’re navigating period pain, migraine, fibromyalgia support, MCAS care, or chronic fatigue care that fits your life, we’ll meet you where you are.
Buy Solpadeine Plus Capsules from Courier Pharmacy
Solpadeine Plus Capsules are a Pharmacy (P) medicine that contains codeine. That means you don’t need a prescription, but the sale must be supervised by a pharmacist who’s checked the product is appropriate for your situation, particularly given the codeine content and the three-day continuous-use limit. MHRA regulations also limit codeine-containing OTC supply to one pack per order in most cases. Here’s how the process works at Courier Pharmacy:
Complete a quick online consultation
A UK GPhC-registered pharmacist reviews your answers
If suitable, your order is approved
We dispense and deliver discreetly to your door
If it isn’t suitable for you, we’ll explain why and suggest the next best option. Sometimes that’s a different combination, sometimes a non-drug approach, sometimes a referral for prescription pain management if attacks are frequent. We also run free fortnightly drop-in clinics and talks at Insomnia, Derby, 10 am to 12 pm. No appointment, no cost, no obligation.
Summary
A UK Pharmacy triple-action painkiller in convenient capsule form
Combines paracetamol, codeine and caffeine for moderate pain
24-capsule pack offers multiple short courses across the year
Strictly short-term use; no more than three days continuously without medical advice
Available from Courier Pharmacy with pharmacist-led advice and discreet UK delivery
Active ingredients in Solpadeine Plus Capsules
Paracetamol 500mg is a familiar analgesic and antipyretic, working centrally on pain perception and the brain's temperature regulation. The exact mechanism remains debated but likely involves COX inhibition in the central nervous system and effects on the endocannabinoid and serotonin systems. It's well-tolerated at standard doses but causes severe liver injury in overdose.
Codeine phosphate hemihydrate 8mg is a weak opioid that converts to morphine in the body via the CYP2D6 enzyme. People vary genetically in how quickly they metabolise codeine, which is one reason responses to it differ. Codeine binds to mu-opioid receptors in the central nervous system, modifying how pain signals are perceived.
Caffeine 30mg is a mild stimulant that boosts paracetamol's analgesic effect, helps combat the fatigue that often accompanies pain, and has a modest analgesic contribution of its own. Each capsule's caffeine is roughly equivalent to a third of a cup of coffee. Solpadeine Plus Capsules also contain maize starch, magnesium stearate, titanium dioxide, erythrosine, patent blue V, quinoline yellow and gelatin.
What is Solpadeine Plus Capsules for?
Solpadeine Plus Capsules are licensed in the UK for the short-term treatment of acute moderate pain that isn't adequately relieved by paracetamol, ibuprofen or aspirin alone. That includes migraine, headache, rheumatic pain, muscular pain, period pain, dental pain, backache, sprains, strains, neuralgia and sciatica.
Solpadeine Plus is not licensed for daily long-term pain management. The three-day continuous-use limit is genuinely important. Chronic pain that needs ongoing management is better served by a clinician-supervised plan, which may include non-opioid options, physical therapy, lifestyle approaches, and where appropriate, prescription analgesics that can be reviewed properly.
A note on chronic illness contexts. People with fibromyalgia, CFS/ME or MCAS often look for combination painkillers when standard options aren't enough. Solpadeine Plus can have a short-term role in flare management for some, but it's not a long-term answer, and the codeine can compound fatigue in CFS/ME. The caffeine can be useful for some but problematic in MCAS or anyone with caffeine sensitivities. We'll explore your specific pattern during the consultation.
How does Solpadeine Plus Capsules work?
Pain is a complex experience involving signalling at the site of damage, transmission through the spinal cord and brainstem, and processing in higher brain centres. A combination painkiller like Solpadeine Plus targets multiple points along that pathway, which can produce better relief than a single ingredient working at one site.
Paracetamol works centrally. Its precise mechanism is still being unpicked, but it likely inhibits central COX enzymes and affects descending pain pathways. The result is reduced pain perception without significant peripheral anti-inflammatory effect. Onset is typically within 30 minutes, peak effect at 60 to 90 minutes.
Codeine binds to mu-opioid receptors in the central nervous system after being converted to morphine by the CYP2D6 enzyme. People classed as 'poor metabolisers' make relatively little morphine and may get limited benefit; people classed as 'ultra-rapid metabolisers' make morphine quickly and can experience side effects more strongly. Most people fall somewhere in the middle.
Caffeine has been shown in trials to enhance paracetamol's analgesic effect by roughly 5-10%, which can translate to clinically meaningful relief at the margins. It also reduces fatigue, which can be a useful side benefit when pain is part of a wider crash. The caffeine dose in Solpadeine Plus (30mg per capsule, up to 240mg at maximum daily dose) is mild compared to coffee but not insignificant.
After you swallow Solpadeine Plus, the three ingredients are absorbed from the gut and reach peak blood levels within 30 to 90 minutes. The combined effect typically lasts four to six hours. Taking Solpadeine Plus with food doesn't change effectiveness but may reduce mild stomach upset for some users.
How to use Solpadeine Plus Capsules
Swallow 1 or 2 capsules with water every 4 to 6 hours as needed. Don't exceed 8 capsules in 24 hours for adults aged 16 and over, or 4 capsules in 24 hours for adolescents aged 12 to 15. Avoid taking Solpadeine Plus within 4 hours of any other paracetamol-containing medicine; check labels on cold-and-flu products, co-codamol, Ultramol, Migraleve and similar carefully.
Take Solpadeine Plus at the earliest point that pain is becoming an issue rather than waiting for it to peak. Painkillers generally work better when started earlier in a pain episode. Stay well hydrated; both codeine and caffeine can have effects compounded by dehydration.
Practical tips from our pharmacists: avoid Solpadeine Plus close to bedtime because caffeine can affect sleep; don't combine with energy drinks or strong coffee because the caffeine adds up; stop Solpadeine Plus as soon as your pain has settled rather than continuing 'just in case'; and keep a pain diary if you find yourself reaching for it more than occasionally, so you can spot patterns and have an evidence-based conversation with a clinician about next steps.
Warnings and precautions for Solpadeine Plus Capsules
Solpadeine Plus Capsules are not suitable for everyone. They must not be used by anyone allergic to paracetamol, codeine or caffeine, in children under 12 years, in adolescents under 18 who have had tonsils or adenoids removed for obstructive sleep apnoea, in known ultra-rapid codeine metabolisers, in anyone with severe breathing problems, in bowel obstruction, in recent head injury or raised intracranial pressure, or in anyone who is breastfeeding.
Codeine carries genuine risks of addiction and dependence with continuous use, which is why the three-day continuous-use limit is non-negotiable. Long-term codeine use can cause withdrawal symptoms when stopped, and regular use of painkillers for headache can cause medication-overuse headache. If your pain is frequent enough that you're using Solpadeine Plus most days, that's the signal to talk to a clinician about the underlying cause. Solpadeine is one of the most commonly named products in UK codeine dependence support services, which speaks to how easy it can be for a sensible short-term treatment to drift into a habit.
Solpadeine Plus must not be combined with other medicines containing paracetamol because of the risk of liver injury from inadvertent overdose. That includes co-codamol, Anadin, Lemsip, Beechams, Migraleve, Veganin, Ultramol, Sudafed combinations and many other cold and flu preparations. Check labels carefully and tell your prescriber and us about everything you take.
Use during pregnancy is not recommended without medical advice. Paracetamol alone is generally considered the safer painkiller in pregnancy, but codeine carries risks particularly late in pregnancy. Solpadeine Plus must not be used while breastfeeding because codeine passes into breast milk and can cause serious effects in babies, including respiratory depression.
Caffeine sensitivity warrants caution. People who are particularly sensitive to caffeine, or who have anxiety, atrial fibrillation, or other conditions affected by stimulants, may find Solpadeine Plus uncomfortable. The 30mg caffeine per capsule adds up at higher doses.
Side effects of Solpadeine Plus Capsules
Most people who use Solpadeine Plus short-term experience no problems beyond mild constipation or feeling slightly drowsy from the codeine. Common side effects include constipation, nausea, dry mouth, mild drowsiness or paradoxical alertness from the caffeine, and occasional dizziness. Many of these settle as the painful episode resolves.
Less common effects include skin rash, abdominal pain, palpitations from caffeine, restlessness, anxiety, and worsening of pre-existing conditions like glaucoma or prostatic hypertrophy. Codeine-related side effects can include itching, mild euphoria, and in some people, paradoxical agitation. Rarely, codeine can cause severe abdominal pain in people who have had their gallbladder removed (Sphincter of Oddi spasm).
Rare but serious effects include allergic reactions ranging from urticaria to anaphylaxis, severe codeine-related breathing problems particularly in ultra-rapid metabolisers, hepatotoxicity from paracetamol (almost always in overdose), and very rare cases of serious skin reactions including Stevens-Johnson syndrome. Long-term codeine use can cause dependence, withdrawal, and medication-overuse headache.
If something feels wrong, trust that signal. Stop Solpadeine Plus and seek urgent medical attention if you experience breathing difficulty, severe drowsiness or confusion, facial swelling, widespread rash, severe abdominal pain, dark urine, jaundice, or signs of paracetamol overdose.
Suspected side effects can and should be reported to the MHRA via the Yellow Card scheme at yellowcard.mhra.gov.uk. Reporting helps build the safety picture for everyone.
Drug interactions with Solpadeine Plus Capsules
Solpadeine Plus interacts with several common medicines. Most importantly, never combine Solpadeine Plus with other paracetamol-containing products. That risks accidental paracetamol overdose, which can cause severe liver injury. Read labels on cold-and-flu products, co-codamol, co-dydramol, Migraleve, Veganin, Ultramol and other combination painkillers carefully.
Other CNS depressants compound the sedative and respiratory-depressant effects of codeine. This includes alcohol, benzodiazepines (diazepam, lorazepam), gabapentin or pregabalin, sleeping tablets, and many antidepressants. Combining these with Solpadeine Plus increases drowsiness, confusion and breathing risk meaningfully.
Monoamine oxidase inhibitors (MAOIs) used for depression can interact unpredictably with codeine and caffeine. Solpadeine Plus should not be taken within two weeks of stopping an MAOI. Other antidepressants, particularly SSRIs, can interact with codeine via shared metabolic pathways.
Caffeine interacts with several medicines: theophylline (used for asthma), some quinolone antibiotics (ciprofloxacin), and some thyroid medicines. Combining Solpadeine Plus with strong coffee, energy drinks, or other caffeinated products can increase jitteriness, palpitations and sleep disruption. Anticoagulants like warfarin can have unpredictable interactions with paracetamol at higher doses, with INR sometimes affected. Lithium levels can be affected by caffeine.
Alcohol significantly increases the risks of both paracetamol-related liver injury and codeine-related sedation. Avoid alcohol while taking Solpadeine Plus. Smoking can affect codeine metabolism via CYP2D6 induction, although the clinical impact is usually modest.
Frequently asked questions about Solpadeine Plus Capsules
What are Solpadeine Plus Capsules used for?
Solpadeine Plus is licensed for the short-term relief of acute moderate pain that isn't adequately relieved by paracetamol, ibuprofen or aspirin alone. That includes migraine, headache, period pain, dental pain, neuralgia, sprains, strains, sciatica and rheumatic or muscular pain. It's not licensed for daily long-term pain management.
How quickly do Solpadeine Plus Capsules work?
Most people feel pain relief beginning within 30 to 45 minutes of taking the capsules. Peak blood levels of all three actives are reached at 30 to 90 minutes, and the combined effect typically lasts four to six hours per dose.
How are Solpadeine Plus Capsules different from Solpadeine Max?
Solpadeine Plus contains paracetamol 500mg, codeine 8mg and caffeine 30mg per capsule. Solpadeine Max contains paracetamol 500mg, codeine 12.8mg and caffeine 30mg per tablet, so it has a higher codeine dose. Solpadeine Max may suit more severe pain but carries a higher risk of codeine-related side effects.
Can I take Solpadeine Plus Capsules with ibuprofen?
Yes, ibuprofen works on a different pathway and can be taken alongside Solpadeine Plus safely. Many people find the combination more effective for stubborn pain than either alone. Stick to standard ibuprofen dosing (200-400mg up to three times daily with food) and mention everything you take during your consultation.
Can I take Solpadeine Plus Capsules with paracetamol or co-codamol?
No, never combine Solpadeine Plus with other paracetamol-containing products. Solpadeine Plus already contains 500mg of paracetamol per capsule, and accidentally exceeding 4g of paracetamol in 24 hours can cause severe liver injury. Read labels on cold-and-flu products, co-codamol and similar very carefully.
Will the caffeine in Solpadeine Plus Capsules keep me awake?
It can. Each capsule contains 30mg of caffeine, roughly a third of a cup of coffee. At maximum daily dose (8 capsules), that's around 240mg, similar to two coffees. Avoid Solpadeine Plus close to bedtime if you're caffeine-sensitive, and consider a non-caffeine alternative if sleep is being affected.
Can Solpadeine Plus Capsules make me drowsy?
The codeine can cause mild drowsiness in some people, while the caffeine can have the opposite effect and add alertness. The net effect varies between individuals. Most people don't experience significant drowsiness, but the first dose is worth taking somewhere where you can rest if it does make you sleepy.
How long can I take Solpadeine Plus Capsules for?
Solpadeine Plus must not be used for more than three days continuously without medical advice. Codeine carries addiction risk, and regular use of painkillers for headache can cause medication-overuse headache. The 24-pack is sized for several short courses over time, not one long stretch of use.
Why is there a one-pack limit on Solpadeine Plus Capsules?
MHRA regulations restrict codeine-containing OTC products to one pack per order in most pharmacies. This is to support the three-day continuous-use limit and reduce the risk of codeine dependence. If you need ongoing pain management, the right next step is a clinical conversation about prescription options or non-drug approaches.
Can I drink alcohol with Solpadeine Plus Capsules?
No. Alcohol significantly increases the risks of both paracetamol-related liver injury and codeine-related sedation and breathing depression. Avoid alcohol while taking Solpadeine Plus. If you've had alcohol earlier in the day and are now in pain, plain paracetamol or ibuprofen are usually safer choices until the alcohol has cleared.
Will Solpadeine Plus Capsules interact with my antidepressants?
It depends on the antidepressant. SSRIs can affect codeine metabolism. MAOIs interact unpredictably with codeine and caffeine and must not be taken within two weeks of Solpadeine Plus. Tricyclic antidepressants can compound the sedative effect. Tell us about every antidepressant during your consultation.
Can I drive while taking Solpadeine Plus Capsules?
For most people, yes. A minority experience drowsiness from the codeine that could affect concentration. If you notice any unusual sedation, don't drive or operate machinery. UK driving laws also include specific limits for codeine; for therapeutic use at recommended doses, you should be fine, but stop driving if you feel impaired.
Are Solpadeine Plus Capsules safe in pregnancy?
Solpadeine Plus is not recommended in pregnancy without medical advice. Paracetamol alone is generally considered the safer painkiller in pregnancy. Codeine carries risks particularly late in pregnancy. Solpadeine Plus must not be used while breastfeeding because codeine passes into breast milk and can cause serious effects in babies.
Can children take Solpadeine Plus Capsules?
Solpadeine Plus is suitable for adolescents aged 12 and over at an age-appropriate dose. Children aged 12-15 take 1 capsule every 6 hours, maximum 4 in 24 hours. Children under 12 must not take Solpadeine Plus because of codeine breathing risks. Under-18s who have had tonsils or adenoids removed for sleep apnoea must also not take it.
What is medication-overuse headache?
Medication-overuse headache is a paradox: using painkillers regularly for headache eventually causes more headaches. Codeine-containing products like Solpadeine Plus are particularly likely to cause this. If you find yourself needing headache treatment most days, see a clinician about prevention rather than continuing acute treatment.
Can Solpadeine Plus Capsules cause addiction?
Yes. Codeine is an opioid, and even at the low 8mg dose in Solpadeine Plus, continuous use beyond three days can lead to physical dependence and addiction. This is well recognised, and Solpadeine is one of the more commonly named products in UK codeine dependence support services. Stick to the three-day limit and talk to a clinician if you find pain returning whenever you stop.
Can people with MCAS take Solpadeine Plus Capsules?
Some people with MCAS tolerate Solpadeine Plus well; others react to codeine, caffeine, or excipients including the capsule shell colourings (erythrosine, patent blue V, quinoline yellow). We always review the full ingredient list during your consultation if you have known mast cell reactivity, and where appropriate we can discuss whether a different formulation suits you better.
How are Solpadeine Plus Capsules stored?
Store below 25°C, in the original packaging, away from direct sunlight and moisture. Keep out of sight and reach of children. The codeine content means safe storage matters more than for some other medicines. Return any unused capsules to a pharmacy for safe disposal rather than household waste.
What happens if I take too much Solpadeine Plus Capsules?
Seek immediate medical advice, even if you feel okay. Paracetamol overdose can cause severe liver damage that may not be apparent for hours. Codeine overdose can cause drowsiness, breathing problems and unconsciousness. Take the packaging with you to the hospital or call 999.
How do I order Solpadeine Plus Capsules from Courier Pharmacy?
Complete the short online consultation on our site, and a UK GPhC-registered pharmacist will review your answers, paying particular attention to codeine safety and any history of medication-overuse headache. If Solpadeine Plus is suitable, your order is approved, our pharmacy dispenses the pack and delivers it discreetly to your door. If it isn't suitable, we'll tell you why.
Disclaimer: This article is for general information only and isn’t a substitute for personal medical advice, diagnosis, or treatment. Always check with a GP, pharmacist, or specialist before starting a new supplement if you have a medical condition or take regular medicines.
More than a prescription: our community
Healthcare shouldn't only happen when you're paying for it. Every fortnight we run free drop-in talks and clinics at Insomnia, Derby, from 12pm to 1pm. Bring a question, bring a friend, bring a stack of bewildering letters from another clinic; we'll sit with you. We cover chronic pain, hair loss, men's health, MCAS, fibromyalgia, low-dose naltrexone, and whatever else people bring through the door. No appointment. No cost. No pressure.
How this content was created
Written by the Courier Pharmacy editorial team and reviewed by a GPhC-registered pharmacist. Grounded in the latest NHS, NICE, BNF and EMC guidance, peer-reviewed studies, and the real questions patients bring to our drop-in clinics in Derby.
Joint Formulary Committee (2026) British National Formulary: Paracetamol. London: BMJ Group and Pharmaceutical Press. Available at: https://bnf.nice.org.uk/drugs/paracetamol/
National Institute for Health and Care Excellence (2021) Headaches in over 12s: diagnosis and management. NICE Guideline CG150. London: NICE. Available at: https://www.nice.org.uk/guidance/cg150
