Name: Syndol Headache Relief Tablets (30)
Availability: InStock

What is Syndol?

Syndol Film-coated Tablets (referred to as Syndol) contain four active ingredients: caffeine, codeine phosphate, doxylamine succinate, and paracetamol. These ingredients work together to provide effective relief from pain and discomfort:

Paracetamol: A painkiller (analgesic) and fever reducer (antipyretic).
Codeine phosphate: A painkiller that enhances the effects of paracetamol.
Doxylamine succinate: An antihistamine that helps with symptoms like a runny nose and sneezing.
Caffeine: A mild stimulant that helps improve the effectiveness of the other ingredients.

Syndol offers combined pain relief for various conditions. You can purchase Syndol online from courierpharmacy.co.uk after completing an online consultation form.

What are the active ingredients in Syndol?

Syndol Headache Relief tablets contain three key active ingredients:

Paracetamol 500mg
Caffeine 30mg
Codeine Phosphate 8mg

These ingredients work together to provide effective relief from headache pain. You can purchase Syndol online from courierpharmacy.co.uk after completing the online consultation form.

What is Syndol used for?

Syndol is used to manage short-term moderate pain that is not relieved by common painkillers like paracetamol, ibuprofen, or aspirin. It is effective for treating various types of pain, such as:

Headaches, including muscle tension and contraction headaches
Migraines
Neuralgia (nerve pain)
Period pain
Toothache and other dental pain
Muscular and rheumatic pain
Post-surgery or post-dental procedure pain

Codeine, one of Syndol's active ingredients, can be used for children over 12 years old to relieve moderate pain when other painkillers aren’t effective. However, it is not suitable for children under 18 who have had tonsil or adenoid removal due to Obstructive Sleep Apnoea Syndrome.

You can order Syndol online at courierpharmacy.co.uk after completing the online consultation form.

How does Syndol work?

Syndol Headache Relief tablets contain a combination of active ingredients—paracetamol, codeine, and caffeine—that work together to provide quick and effective pain relief. Syndol Original tablets have the same ingredients, with the added benefit of doxylamine.

Paracetamol is a painkiller that helps relieve mild to moderate pain and reduce fever. It works by lowering the production of prostaglandins in the brain and spinal cord, chemicals that cause pain by making nerve endings more sensitive. This helps reduce the intensity of pain.
Codeine is an opioid painkiller that works by mimicking the body’s natural pain-relieving chemicals, known as endorphins. It blocks pain signals from the nerves to the brain, reducing the perception of pain while the cause remains.
Caffeine acts as a mild stimulant that boosts the pain-relieving effects of paracetamol while helping to reduce the drowsiness that can be caused by codeine.

Syndol Original tablets also contain doxylamine, an antihistamine commonly used to treat allergy symptoms. When combined with the other ingredients, doxylamine helps relieve muscle tension and contributes to alleviating tension headaches and muscle pain.

To purchase Syndol online, complete the online consultation form at courierpharmacy.co.uk.

How to take Syndol

Always follow the instructions provided by your doctor or pharmacist. If you have any doubts, ask them for advice.

Duration of Use

Do not use Syndol for longer than 3 days without consulting a healthcare professional. If you need to take it for longer, speak with your doctor or pharmacist.

Addiction Risk

Syndol contains codeine, which can lead to addiction if used for more than three days. If you stop taking it, you may experience withdrawal symptoms. If this happens, consult your doctor or pharmacist.

Dosage Instructions

Adults (including the elderly):

Take one or two tablets every 4 to 6 hours as needed.
Wait at least 4 hours before taking another dose.
Do not exceed 8 tablets in 24 hours.
If you are elderly or have a weakened state, ask your doctor for guidance on the correct dose.

Children aged 16 to 18 years:

Take 1 to 2 tablets every 6 hours as needed.
Do not exceed 8 tablets in 24 hours.

Children aged 12 to 15 years:

Take 1 tablet every 6 hours as needed.
Do not exceed 4 tablets in 24 hours.

Children under 12 years:

Syndol is not suitable for children under 12 years old due to the risk of serious breathing issues.

If You Take Too Much Syndol

Symptoms of overdose may include pale skin, nausea, vomiting, loss of appetite, stomach pain, pinpoint pupils, difficulty breathing, irregular heartbeat, or kidney pain.
Seek medical help immediately, even if you feel fine. Paracetamol overdose can cause severe liver damage, which may be delayed.
Take any remaining tablets and packaging with you when seeing a doctor.

If You Forget a Dose

Take your dose as soon as you remember, unless it’s almost time for your next dose. In this case, skip the missed dose.
Do not take two doses at once to make up for a missed one.
Always wait at least 4 hours between doses.

If You Stop Taking Syndol

As Syndol contains codeine, stopping after prolonged use may cause withdrawal symptoms. If this happens, contact your doctor or pharmacist for support.

To buy Syndol, visit courierpharmacy.co.uk and complete the online consultation form.

Who should not take Syndol?

Before taking Syndol, it's important to be aware of the following key warnings.

Addiction Warning

Syndol contains codeine, which can lead to addiction if used for more than 3 days. Stopping the medication after this time may cause withdrawal symptoms.

Headache Warning

Prolonged use of Syndol to treat headaches (over 3 days) could potentially make headaches worse.

Do Not Take Syndol If:

You are allergic to any of the ingredients, including codeine, paracetamol, doxylamine succinate, caffeine, or others listed in section 6.
You are currently having an asthma attack or have severe breathing issues.
You have recently had a head injury.
You have been diagnosed with increased pressure in your head (e.g., headaches, blurred vision, vomiting).
You have recently had surgery on your liver, gallbladder, or bile ducts.
You are at risk of a blocked intestine (paralytic ileus).
You are already taking other medications with codeine or paracetamol.
You are currently taking, or have recently taken, Monoamine Oxidase Inhibitors (MAOIs) for depression (e.g., selegiline, moclobemide).
You have a history of alcohol use disorder.
You are under 12 years old.
You are under 18 years old and have had your tonsils or adenoids removed due to Obstructive Sleep Apnoea Syndrome.
You metabolize codeine into morphine too quickly.
You are breastfeeding or planning to breastfeed.

Warnings and Precautions

Consult your doctor or pharmacist before taking Syndol if you have:

Liver, kidney, thyroid, or heart issues, or if you are elderly or frail.
High blood pressure, prostate problems, or any bowel issues.
Recent abdominal surgery or gastrointestinal issues like ulcers.
A history of seizures, gallstones, glaucoma, or myasthenia gravis.
Mental health issues, or if you are undergoing psychiatric treatment.
You are taking benzodiazepines (e.g., diazepam, lorazepam) for anxiety or sleep disorders.

How Codeine Works

Codeine is converted into morphine in the liver, providing pain relief. Some people may metabolize it too quickly, leading to serious side effects. If you experience slow breathing, confusion, dizziness, small pupils, nausea, constipation, or loss of appetite, stop taking Syndol and seek immediate medical attention.

Taking Syndol with Food and Drink

Avoid drinking alcohol while using Syndol.

For Children and Adolescents

Do not use Syndol for children who have had tonsil or adenoid surgery due to Obstructive Sleep Apnoea Syndrome.
Do not use Syndol for children with breathing issues as symptoms of morphine toxicity could be more severe.

Pregnancy and Breastfeeding

If you are pregnant, breastfeeding, or planning to have a baby, consult your doctor before using this medication.
Do not take Syndol if you are in the last trimester of pregnancy or in labor.
Avoid breastfeeding while taking Syndol, as it can pass into breast milk.

Driving and Using Machines

Syndol may cause drowsiness or dizziness, affecting your ability to drive.
Do not drive until you know how Syndol affects you. It’s an offense to drive impaired.
If prescribed for a medical condition and used as directed, you may drive if you feel able to do so safely.

Important Information About Ingredients

Lactose: Syndol contains lactose. If you are intolerant to certain sugars, consult your doctor.
Color Additives: This medication contains sunset yellow (E110) and quinoline yellow (E104), which may cause allergic reactions.
Sodium: Syndol contains less than 1 mmol sodium per tablet, making it essentially sodium-free.

For more information or to buy Syndol, complete an online consultation at courierpharmacy.co.uk.

What are the side effects of Syndol?

Syndol, like all medications, can cause side effects, although not everyone experiences them. Below are some potential side effects.

Seek Medical Help Immediately If You Experience:

A rash, fever, swelling, bruising, or unusual tiredness.
Difficulty breathing or feeling dizzy.
Swelling in the hands, feet, ankles, face, lips, or throat, which could cause trouble swallowing or breathing.
An itchy rash (hives) or nettle rash (urticaria), which could indicate an allergic reaction.
Rare but serious skin reactions.

Contact Your Doctor Right Away If You Notice:

Severe stomach pain that radiates to your back, which could signal inflammation of the pancreas (pancreatitis).
Increased likelihood of infections or easy bruising, which could point to a blood disorder like agranulocytosis or thrombocytopenia.
Yellowing of the skin or eyes (jaundice).

Tell Your Doctor or Pharmacist If You Experience These Side Effects:

Nausea or vomiting.
Low blood pressure, causing dizziness or fainting when standing.
Confusion or depression.
Trouble sleeping, shaking, or seizures.
Irregular heartbeat.
Stomach pain, sweating, or facial flushing.
General discomfort or loss of appetite.
Very slow or shallow breathing.
Shortness of breath.
Hallucinations or nightmares.
Muscle cramps or stiffness.
Developing a dependence on codeine.

Other Possible Side Effects:

Constipation, headache, drowsiness, dizziness, restlessness.
Trouble passing urine, dry mouth, blurred vision.
Diarrhea or thick phlegm.

How Do I Know if I’m Addicted?

While following the instructions should prevent addiction, it’s important to consult your doctor if:

You feel the urge to take the medicine longer than recommended.
You need to take higher doses to achieve the same effect.
You feel unwell when stopping the medication, but better when resuming it.

Reporting Side Effects

If you experience any side effects, including those not listed here, speak to your doctor, pharmacist, or nurse. You can also report side effects through the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or by searching for "MHRA Yellow Card" in the Google Play or Apple App Store. Reporting side effects helps improve the safety of this medicine.

To purchase Syndol online, complete the online consultation form at courierpharmacy.co.uk.

Does Syndol interact with other medicines?

It's important to inform your doctor or pharmacist if you are currently taking or have recently taken any other medications, including those available without a prescription, such as herbal remedies. Syndol can interact with other medicines, potentially affecting how they work or how Syndol works.

Avoid Other Medications Containing Paracetamol

While using Syndol, do not take any other medicines that contain paracetamol. This includes many painkillers, cough and cold treatments, and various over-the-counter medications.

Do Not Take Syndol If You Are Taking:

Medicines for depression known as MAOIs (monoamine oxidase inhibitors), or if you have taken them in the last two weeks. Examples include moclobemide, phenelzine, and tranylcypromine.

Tell Your Doctor or Pharmacist If You Are Taking or Have Recently Taken:

Medicines that cause drowsiness or sleepiness (CNS depressants), such as barbiturates, anesthetics, hypnotics, other opioid painkillers, anxiolytic sedatives, antipsychotics, tricyclic antidepressants, phenothiazines, or benzodiazepines used for anxiety or sleep disorders.
Medicines for high blood pressure (diuretics and antihypertensives).
Antidepressants used to treat clinical depression.
Antipsychotics for mental health conditions.
Antimuscarinics, such as atropine or hyoscine.
Neuromuscular blockers like tubocurarine.
Blood thinners like warfarin (or other coumarins).
Metoclopramide or domperidone, used for nausea or vomiting.
Colestyramine, for lowering cholesterol.
Hydroxyzine, for anxiety and tension.
Mexiletine, for irregular heartbeat.
Kaolin or loperamide, for diarrhea.
Naloxone, for narcotic overdose.
Naltrexone, used for drug or alcohol dependence.
Cimetidine, for stomach ulcers.
Cisapride, for gastroesophageal reflux disease.
Quinidine, for irregular heart rate.
Oral contraceptive pills.

Consult Your Doctor or Pharmacist Before Taking Syndol If:

If you are unsure whether any of the above applies to you, always consult your doctor or pharmacist before using Syndol.

Risk of Taking Opioids and Benzodiazepines Together

Taking opioids and benzodiazepines together increases the risk of drowsiness, breathing problems (respiratory depression), coma, and even death. Always follow your doctor’s dosage instructions carefully. It's also recommended to have friends or family observe you for any signs or symptoms. Contact your doctor immediately if you notice any concerning symptoms.

To purchase Syndol online, complete the online consultation form at courierpharmacy.co.uk.

Syndol Tablets FAQs

What are Syndol Tablets?

Syndol Tablets are designed to offer fast and effective short-term pain relief when typical over-the-counter painkillers like paracetamol are not enough. These tablets help with mild to moderate pain caused by conditions such as headaches, migraines, nerve pain (neuralgia), period pain, toothache, and rheumatic aches. Syndol provides a stronger pain relief option for people whose pain isn’t managed by regular painkillers like paracetamol or ibuprofen.

What are Syndol Tablets used for?

Syndol Tablets are intended to provide short-term relief for various types of acute pain, including:

Headaches
Migraines
Toothache
Nerve pain (neuralgia)
Period pain
Muscle pain

There are two main types of Syndol Tablets:

Syndol Headache Relief Tablets: Contain paracetamol, codeine, and caffeine, specifically targeting headaches and migraines.
Syndol Original Pain Relief Tablets: Include doxylamine, a muscle relaxant that helps relieve tension headaches, muscle pain, toothache, period pain, and neuralgia.

Syndol should only be used when regular painkillers such as paracetamol or ibuprofen aren’t enough and is intended for short-term use (up to 3 days) due to the risk of addiction.

How does Syndol work?

Syndol tablets combine multiple active ingredients to relieve pain effectively:

Paracetamol reduces mild to moderate pain and fever by lowering the production of pain-causing chemicals in the body.
Codeine is an opioid painkiller that helps block pain signals to the brain.
Caffeine acts as a mild stimulant, boosting the effects of paracetamol while reducing the drowsiness caused by codeine.
Doxylamine (in Syndol Original) is a sedating antihistamine that also works as a muscle relaxant to reduce muscle pain and tension.

What are alternatives to Syndol Tablets?

If you’re looking for other non-prescription pain relief options, consider:

Ibuprofen
Paracetamol
Aspirin
Topical treatments (e.g., ibuprofen gel)

For migraines, you may find Migraleve Yellow and Migraleve Pink tablets helpful, as they combine pain relief with a substance that can reduce nausea linked to migraines.

If Syndol does not relieve your pain within 3 days, you should consult your doctor or pharmacist.

Can I take Syndol Tablets with paracetamol?

No, you should not take Syndol alongside any other product that contains paracetamol. This can lead to an overdose, causing potential damage to your liver and kidneys. Always check the ingredients of other medications before taking Syndol. If you're unsure, ask your pharmacist for guidance.

What are the ingredients in Syndol Tablets?

Syndol Headache Relief Tablets: Paracetamol 500mg, Caffeine 30mg, Codeine Phosphate 8mg.
Syndol Original Tablets: Includes Doxylamine Succinate 5mg.

Other ingredients in both variants include povidone, maize starch, methylcellulose, talc, purified water, and calcium stearate.

What should I be aware of before taking Syndol Tablets?

Do not take Syndol if:

You are allergic to any of the ingredients.
You have asthma, severe respiratory issues, alcohol dependency, or have recently undergone bile duct surgery.
You have paralytic ileus (a condition where the bowel doesn’t function), or have recently had a head injury or raised skull pressure.
You are pregnant or breastfeeding.

Consult your doctor if you have any of the following conditions:

Kidney or liver problems
Enlarged prostate
Low blood pressure
Bowel issues
Underactive thyroid

Can Syndol interact with other medicines?

Yes, Syndol can interact with various medications. Do not take it if you are currently using or have recently used:

Monoamine Oxidase Inhibitors (MAOIs), antidepressants, or similar medications.

Always speak to your doctor or pharmacist before taking Syndol if you're using other medications, whether prescribed or over-the-counter.

Can I drive while taking Syndol?

Syndol may cause drowsiness. If you feel drowsy, avoid driving, operating heavy machinery, or consuming alcohol while taking Syndol.

To purchase Syndol online, complete the online consultation form at courierpharmacy.co.uk.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.750.pdf

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How does Syndol work?