A low-to-moderate dose pressurised metered-dose preventer inhaler containing beclometasone dipropionate 100 micrograms for the daily management of mild-to-moderate asthma in adults and children. Supplied at Courier Pharmacy after an online consultation reviewed by a UK pharmacist prescriber.
Soprobec 100 is a prescription-only preventer inhaler for the long-term management of asthma. Firstly, it contains beclometasone dipropionate 100 micrograms per puff (actuation) — an inhaled steroid (ICS). In plain English, it treats the swelling inside the airways that causes asthma symptoms and raises the risk of attacks.
Furthermore, Soprobec 100 is a pressurised metered-dose inhaler (pMDI) — a standard press-and-breathe inhaler. Additionally, each inhaler holds 200 puffs, which lasts about 50 days at a typical adult dose of 2 puffs twice daily (if your prescriber has set that dose).
Cut down how often you need your blue reliever inhaler
Lower the risk of asthma flare-ups over time
Above all, it is a controller medicine. So it works best when you use it every day, even when you feel well.
How beclometasone works (preventer vs reliever)
Firstly, asthma is mainly a long-term inflammatory condition. When the airway lining swells up, the airways become more sensitive and narrow more easily.
Meanwhile, your reliever inhaler (usually salbutamol) relaxes airway muscles quickly, so it helps in the moment. In contrast, your preventer inhaler (like Soprobec) treats the underlying swelling, so symptoms and attacks become less likely.
Furthermore, beclometasone helps by:
Calming inflammatory activity in the airway lining
Cutting mucus production
Reducing airway “twitchiness” to triggers
Lowering how often and how severely asthma attacks happen
As a result, the benefit builds over 1–2 weeks of regular use.
Who Soprobec 100 is usually for
Firstly, Soprobec comes in four strengths (50, 100, 200, 250 micrograms). Notably, the 100 microgram strength suits:
Adults newly diagnosed with ongoing asthma (often Step 2)
Adults with mild to moderate ongoing asthma as an initial maintenance dose
Children (usually age 4+) who need more than the lowest dose
People stepping up from Soprobec 50 because symptoms were not fully controlled
People stepping down from higher strengths once control is stable
In UK general practice, Soprobec 100 is often the standard starting point for many adults.
Soprobec 100 vs Clenil Modulite 100 vs Qvar: what’s the difference?
Firstly, Soprobec 100 vs Clenil Modulite 100 — both hold the same medicine (beclometasone) at the same strength, but different makers produce them. Clinically, they work the same, although some people notice small differences in taste or feel.
Furthermore, Soprobec 100 vs Qvar — Qvar is beclometasone too, but it is an extra-fine particle inhaler and uses different dosing. Roughly, Qvar 50 micrograms can match standard beclometasone 100 micrograms in effect. However, do not swap without clinical advice.
How to use Soprobec 100 (device and technique)
Because Soprobec 100 is a pMDI:
Firstly, shake the inhaler before each use
Then, use good press-and-breathe technique
Additionally, a spacer can make it easier and improve delivery to the lungs (especially for children)
Above all, if your technique is off, the medicine often lands in your mouth or throat instead of your lungs, which reduces benefit.
Mouth care: rinse after use
Like other inhaled steroids, Soprobec can sometimes cause:
Hoarse voice
Sore throat
Oral thrush
Therefore, to lower this risk:
Rinse your mouth and spit after use (or brush your teeth)
When to review your asthma control
Firstly, if you use your blue reliever inhaler more than 3 times a week, wake at night, or need bigger doses, this usually means your asthma needs a review. Furthermore, it may need a step-up in preventer treatment.
How we supply Soprobec 100 at Courier Pharmacy
At Courier Pharmacy, we supply Soprobec 100 only against a valid prescription. Furthermore, a UK pharmacist prescriber reviews every request. During the review, we will discuss your asthma control, how often you use your reliever, your inhaler technique (and spacer use if relevant). Then, we confirm that Soprobec 100 matches your current asthma management step.
Key features and specifications
Active ingredient: Beclometasone dipropionate 100 micrograms per actuation
Form: Pressurised metered-dose inhaler (pMDI)
Pack size: 200 actuations
Class: Inhaled steroid (ICS) preventer
Legal status (UK): Prescription-only medicine (POM)
Typical adult use (as directed): Often 2 puffs twice daily (total 400 micrograms daily)
Onset: Effect builds over 1–2 weeks with regular use
Storage: Store below 25°C
Additional information
Quantity
1 inhaler, 2 inhalers, 3 inhalers
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Asthma that needs more than a reliever — the cough that won’t quite settle, the wheeze most mornings, the reliever you’re reaching for 3 or 4 times a week.
Maybe your GP has started you on a preventer for the first time. Maybe you’ve stepped up from Soprobec 50 because the lower dose wasn’t holding control. Maybe your dispenser has supplied Soprobec instead of the Clenil you’d been on, and you want to know it’s the same drug.
Soprobec 100 is a pressurised metered-dose inhaler containing beclometasone dipropionate 100 micrograms per actuation — a low-to-moderate-dose inhaled corticosteroid (ICS) made by Glenmark Pharmaceuticals.
For most adults newly starting preventer therapy, this is the typical starting strength. At Courier Pharmacy we want you to understand exactly how it works, the rinse-and-spit technique, spacer use, and where it sits in the asthma management ladder.
Five key takeaways
Soprobec 100 is a pressurised metered-dose inhaler (pMDI) containing beclometasone dipropionate 100 micrograms per actuation. A low-to-moderate-dose inhaled corticosteroid (ICS) preventer used in the prophylactic management of mild-to-moderate asthma in adults and children. Standard pack contains 200 actuations. Manufactured by Glenmark Pharmaceuticals as a generic equivalent to Becotide and similar to Clenil Modulite.
This is a PREVENTER, not a reliever. Taken daily even when feeling well, not when you have an attack. The anti-inflammatory effect builds over 1-2 weeks of consistent use, with full benefit typically by 4-6 weeks. Reliever (SABA) remains essential for acute symptoms.
Standard adult use is 2 puffs twice daily (400 micrograms total daily dose) — the typical entry point for adult preventer therapy at Step 2 of asthma management. Step-up to Soprobec 200 or 250, or to a combination ICS-LABA, if control is inadequate.
Critical technique points: shake before use, slow inhalation coordinated with actuation, 10-second breath hold, and rinse-and-spit after use. A spacer (Volumatic, AeroChamber) significantly improves drug delivery and reduces oral side effects — strongly recommended.
Suitable as Step 2 of the BTS/SIGN asthma ladder for most newly-diagnosed adult asthma. The 100 microgram strength is the most commonly prescribed preventer dose in UK general practice. Generic equivalent of Becotide — cost-effective alternative to branded beclometasone inhalers.
Treatment dosage of Soprobec 100
The standard adult dose is 2 puffs twice daily, taken regularly even when feeling well.
Standard adult use:
2 puffs twice daily (morning and evening, approximately 12 hours apart)
Total daily dose: 400 micrograms beclometasone — the typical adult low-dose entry
Continue daily regardless of symptoms
Standard paediatric use (4-11 years):
1-2 puffs twice daily, individualised to control
Spacer recommended for all paediatric use
The pMDI technique step by step:
Remove the cap and check the mouthpiece is clean
Shake the inhaler vigorously for 5 seconds
Breathe out slowly and gently away from the inhaler
Hold the inhaler upright (mouthpiece down)
Place mouthpiece between teeth, seal lips around it
As you start a slow, deep breath in, press the canister down to release a puff
Continue inhaling slowly for 4-5 seconds
Hold breath 10 seconds
Exhale slowly away from the inhaler
Wait 30 seconds before second puff
Repeat for second puff
Rinse mouth with water and spit out
With a spacer (strongly recommended):
Shake inhaler
Insert into spacer
Place spacer mouthpiece in mouth (or use mask in children)
Press canister to release puff into spacer
Breathe in slowly and deeply through spacer (or 4-5 normal breaths for young child)
Hold breath 10 seconds if able
Wait 30 seconds, repeat for second puff
Rinse and spit afterwards
Why a spacer matters:
Lung deposition: 10-20% without spacer; 20-30% with spacer
Coordination problem largely solved
Less drug in mouth and throat = less thrush, less dysphonia
BTS strongly recommends spacer use; NICE NG80 includes spacer in technique guidance
Why rinse-and-spit matters:
The portion of dose deposited in mouth/throat can cause:
Oral candidiasis (thrush)
Dysphonia (hoarseness)
Mild systemic absorption from oral mucosa
A 10-second water rinse and spit prevents most of these problems. It’s not optional — it’s part of the dose technique.
Practical tips:
Routine pairing — link inhaler use to teeth brushing morning and evening
Always shake — pMDIs need it
Slow inhalation — unlike DPIs, this is gentle and deep
Spacer when available
Always rinse and spit
Check dose counter if your device has one
Don’t double up missed doses — just resume
Store at room temperature
For specific situations:
Travel: carry-on luggage
During illness: continue preventer; reliever use may temporarily increase
Before exercise: SABA 15 minutes before; Soprobec daily continues
Stepping up: GP may suggest Soprobec 200 or 250, or move to combination inhaler
Stepping down: GP may suggest Soprobec 50, or reducing puffs
Don’t use Soprobec 100 if:
You have known hypersensitivity to beclometasone dipropionate or any excipient
You are using it as a reliever during acute attack (use SABA instead)
Use with care if:
You have active untreated TB or other chronic infections
You have recurrent oral candidiasis
You have diabetes (high doses can affect glucose; less concern at 400 mcg daily)
You are pregnant or breastfeeding (use generally considered acceptable)
You have severe hepatic impairment
You are an elderly patient with osteoporosis risk
When to seek medical attention:
Reliever use more than 3 times a week despite consistent Soprobec
Nocturnal symptoms
Worsening symptoms
Acute attack not responding to reliever — call 999
White mouth patches (thrush)
Persistent hoarseness
Worsening cough with sputum/fever (chest infection)
Overview of Soprobec 100
Five things worth knowing:
Soprobec 100 at 2 puffs twice daily is the typical entry point for adult preventer therapy. 400 micrograms beclometasone daily is firmly in the low-dose category and is suitable for most newly diagnosed mild-to-moderate adult asthma. If you’re starting preventer therapy for the first time, this is most likely the dose your GP will choose.
The preventer-not-reliever distinction is the foundation of effective use. Daily taken regardless of symptoms is the entire principle. Patients who only use the preventer when symptomatic experience repeated cycles of inflammation re-establishing itself.
Spacer use significantly improves outcomes. Studies consistently show 2-3x better lung deposition with spacer, and lower oral side effects. For children, BTS considers spacer use essential. For adults, evidence is strongly supportive.
Rinse and spit after every dose. Oral thrush and dysphonia are the most common preventable side effects. Ten seconds of rinsing prevents most cases.
Brand-switching context: Soprobec, Clenil, and Qvar all contain beclometasone, but Qvar has extra-fine particles meaning dosing differs (Qvar 50 ~ Soprobec 100). Standard beclometasone brands (Soprobec, Clenil) are clinically equivalent at matched strengths. Always tell your GP if your brand has been switched.
The UK asthma treatment ladder positions Soprobec 100 (and equivalent) at Step 2 — the foundational preventer step. Movement between strengths (50, 100, 200, 250) is based on:
Step up if reliever use exceeds 3 times a week
Step up if nocturnal symptoms more than 1 night a week
Step up if exacerbations needing oral steroids
Step down if good control sustained for 3+ months
For people living with asthma, the preventer is the foundational long-term medication. The reliever provides symptom relief but the preventer prevents the underlying disease worsening.
Why choose Courier Pharmacy for Soprobec 100
The preventer inhaler is the foundation of long-term asthma management — but it only works with consistent use and good technique. Every Soprobec supply at Courier Pharmacy is reviewed by a UK pharmacist prescriber who checks indication, technique, and your overall regimen.
We’ll discuss the preventer-not-reliever principle. Daily taken regardless of how you feel. The effect builds over weeks.
We’ll explain the pMDI technique. The shake, the slow coordinated inhalation, the breath hold, the wait between puffs, the rinse-and-spit. 60-80% of pMDI users have technique errors. We can check yours at our community drop-ins.
We’ll recommend spacer use. For children, essential per BTS. For adults, strongly recommended.
We’ll discuss strength choice. Soprobec 100 is the typical adult entry dose. If your control suggests you need more, we can discuss stepping up.
We’ll explain the brand context. Soprobec, Clenil, Qvar — all beclometasone, but Qvar dosing differs because of extra-fine particles. Soprobec and Clenil are interchangeable at matched strengths.
Our brand guide, Dr Ada Jex-Cori, sums it up: you’re not broken. The system that’s failed you might be. We want to do the part we can do, properly, and connect you with the rest. That includes our free fortnightly drop-in clinics and talks at Insomnia in Derby.
Buy Soprobec 100 from Courier Pharmacy
Soprobec 100 is a prescription only medicine in the UK.
Complete a quick online consultation
A UK pharmacist prescriber reviews your information
If suitable, a prescription is issued
We dispense and deliver discreetly
If it isn’t suitable, we’ll explain why and suggest the next best option.
Active ingredients in Soprobec 100
The active ingredient is beclometasone dipropionate.
Chemical and pharmacological class:
Inhaled corticosteroid (ICS)
Synthetic glucocorticoid
Pro-drug — converted to active beclometasone-17-monopropionate (B-17-MP) by esterases in lung tissue
Among the longest-used ICS molecules
Standard particle size formulation (vs Qvar extra-fine)
Mechanism of action:
Diffuses across bronchial cell membranes
Binds to cytoplasmic glucocorticoid receptors
Receptor-ligand complex enters nucleus
Modifies gene expression
Reduces inflammatory cell infiltration
Down-regulates cytokine production
Reduces mucus secretion
Reduces airway hyperreactivity
Effect builds over days to weeks
Pharmacokinetics:
Lung deposition with pMDI: 10-20% (higher with spacer)
Conversion to active B-17-MP in lung tissue
Half-life: B-17-MP approximately 2.5-3 hours
Metabolism: hepatic
Excretion: predominantly faecal
Dose-equivalence:
In ICS comparison:
Beclometasone (standard) 400 mcg ~ Beclometasone (extra-fine, Qvar) 200 mcg
Beclometasone 400 mcg ~ Fluticasone propionate 200 mcg
Beclometasone 400 mcg ~ Budesonide 400 mcg
400 mcg daily of beclometasone is at the upper edge of the low-dose range; some references classify 400-800 mcg as the medium range.
Other excipients include HFA-134a propellant and ethanol.
What is the Soprobec 100 inhaler used for
Soprobec 100 is used in adults and children (4+) for:
Initial preventer therapy in newly diagnosed mild-to-moderate persistent asthma
Maintenance therapy in patients with stable asthma controlled on this dose
Step-up from Soprobec 50 when control isn't adequate at the lower dose
Step-down option from higher-strength preventers
Appropriate for:
Daily long-term use
Combined with SABA reliever
Adults and older children with pMDI technique
Patients newly at Step 2 asthma management
Not appropriate for:
Acute attacks (use SABA)
Severe asthma where higher-strength or combination is needed
Patients with beclometasone hypersensitivity
Children under 4
Sole inhaler in asthma (SABA always needed)
NICE NG80, BTS/SIGN, and GINA all support low-dose ICS at the foundation of asthma management.
How does Soprobec 100 work?
Asthma involves chronic airway inflammation driving hyperreactivity and bronchoconstriction. Soprobec addresses the inflammation.
The inflammatory pathway:
Triggers activate immune cells in the airway
Th2 lymphocytes release cytokines
Eosinophils, mast cells, and other inflammatory cells accumulate
Inflammatory mediators released
Airway becomes hyperreactive
Mucus hypersecretion develops
Beclometasone breaks this cycle by:
Reducing inflammatory cell infiltration
Down-regulating cytokine production
Reducing mast cell sensitisation
Reducing eosinophil-mediated damage
Reducing baseline airway responsiveness
Reducing mucus secretion
Time course:
Days 1-3: small improvement
Week 1-2: clearer reduction in reliever use
Week 4-6: full benefit established
Months: continued protection while consistent use
Discontinuation: effect dissipates over 1-2 weeks
What it doesn't do:
Doesn't act as reliever
Doesn't cure asthma
Doesn't substitute for trigger avoidance
Doesn't replace SABA
How to use Soprobec 100
Standard pMDI technique:
Remove cap
Shake vigorously
Hold upright (mouthpiece down)
Breathe out slowly
Place mouthpiece in mouth, seal lips
As you start slow deep breath, press canister
Continue inhaling slowly
Hold breath 10 seconds
Exhale slowly
Wait 30 seconds before second puff
Repeat
Rinse mouth and spit
With spacer:
Shake inhaler
Insert into spacer
Mouth on spacer mouthpiece
Press canister, release into spacer
Slow deep inhalation
Hold breath 10 seconds
Wait, repeat for second puff
Rinse and spit
Practical tips:
Daily routine
Always shake
Slow inhalation
Spacer when available
Rinse and spit
Track usage
Don't double up
Store at room temperature
When the inhaler may not work as expected:
Insufficient shake
Poor coordination
Mouthpiece blockage
Cold inhaler
Empty canister
When to seek further advice:
Reliever use exceeds 3 times a week
Worsening symptoms
Acute attack not responding — call 999
Oral thrush
Persistent hoarseness
Warnings and precautions of Soprobec 100
Contraindicated in:
Known hypersensitivity to beclometasone
Use as reliever during acute attack
Use with care in:
Active untreated TB or other respiratory infections
Recurrent oral candidiasis
Diabetes
Pregnancy and breastfeeding
Severe hepatic impairment
Elderly with osteoporosis risk
History of adrenal suppression
The oral candidiasis warning:
ICS use is the principal risk factor for thrush. Rinse-and-spit reduces this significantly. Treatment: nystatin or miconazole; continue ICS.
The dysphonia warning:
Hoarseness, weak voice. Spacer and rinse-and-spit reduce risk.
The systemic effects consideration:
At Soprobec 100 doses (400 mcg daily), systemic effects are minimal. Higher doses (above 1000 mcg) carry more concern for:
HPA axis suppression
Bone density effects
Cataracts and glaucoma
Growth velocity in children
At 100 microgram strength used standardly, these are not significant concerns for most patients.
Pregnancy and breastfeeding:
ICS generally considered acceptable. Uncontrolled asthma is more dangerous.
Drug interactions:
CYP3A4 inhibitors (ritonavir): rarely significant at this dose
Combined oral corticosteroids: additive systemic effects with long-term use
Hypokalaemia-causing medications: minor concern at this dose
If you experience signs of an allergic reaction (rash, swelling, breathing difficulty), seek immediate medical attention.
Skin rashes, paradoxical bronchospasm (discontinue), behavioural changes (especially in children).
Rare (less than 0.1%):
Angioedema, adrenal suppression (long-term high-dose), bone density changes (long-term high-dose).
Very rare and serious:
Severe allergic reactions, glaucoma, cataracts, severe adrenal crisis.
Report any concerning side effects to MHRA Yellow Card scheme.
Drug Interactions with Soprobec 100
Ritonavir and strong CYP3A4 inhibitors: theoretical concern; rarely significant
Other corticosteroids: additive systemic with high-dose ICS
Diuretics, beta-2 agonists, theophylline: combined hypokalaemia at high doses
Tell your pharmacist about all medicines.
Frequently Asked Questions?
What is Soprobec 100 used for?
Soprobec 100 is a preventer inhaler containing beclometasone 100 micrograms per actuation, used for the daily prophylactic management of mild-to-moderate asthma in adults and children.
Is Soprobec a reliever?
No. Soprobec is a PREVENTER taken daily even when feeling well. For acute attacks you need a SABA (Ventolin, Salbutamol Easyhaler, etc.).
How quickly does it work?
The anti-inflammatory effect builds over 1-2 weeks of consistent use. Full benefit typically by 4-6 weeks.
How is Soprobec 100 different from Clenil 100?
Same drug at same dose; Clenil is by Chiesi, Soprobec by Glenmark. Clinically equivalent.
How is Soprobec 100 different from Qvar 50?
Both contain beclometasone but Qvar uses extra-fine particles. Qvar 50 mcg has roughly the same clinical effect as Soprobec 100 mcg.
What's the typical starting dose for adults?
Soprobec 100 at 2 puffs twice daily (400 mcg daily) is the typical entry dose for adult preventer therapy at Step 2.
Should I use a spacer?
Strongly recommended, particularly for children. Adults benefit too — better lung deposition and lower side effects.
Why must I rinse and spit?
To prevent oral thrush and dysphonia from dose deposited in mouth/throat. 10 seconds, every dose.
Can children use Soprobec 100?
Yes, from age 4+ at appropriate paediatric doses with spacer.
Can I use it during pregnancy?
Yes. ICS generally considered acceptable; uncontrolled asthma is more dangerous to mother and baby.
Is it safe while breastfeeding?
Yes. Negligible transfer to breast milk.
What if I forget a dose?
Take as soon as you remember unless near next dose; don't double up.
Can I stop Soprobec if I feel well?
Don't stop without medical advice. Effect dissipates over 1-2 weeks; symptoms return.
Will Soprobec cure asthma?
No. Controls it. Asthma is chronic; preventer therapy is typically lifelong.
Why does my voice sound different?
ICS deposit in larynx. Rinse-and-spit and spacer use reduce. Persistent dysphonia warrants GP review.
What if I develop thrush?
Treatable with antifungal lozenges or gel. Continue Soprobec; improve technique.
Can I exercise on Soprobec?
Yes. Many patients find exercise tolerance improves. SABA 15 minutes before if needed.
How long should I use it?
For as long as you have asthma — typically lifelong with periodic review.
What if I have a cold?
Continue Soprobec as normal. Reliever use may temporarily rise.
