Frequently asked questions
What is Sustanon 250?
Sustanon 250 is a UK-licensed long-acting testosterone depot injection. Each 1ml ampoule contains four testosterone esters (propionate, phenylpropionate, isocaproate and decanoate) in an arachis oil carrier, delivering 250mg of testosterone per ml.
Can I use Sustanon 250 if I am allergic to peanuts?
No. Sustanon 250 contains arachis (peanut) oil and is contraindicated in anyone with a known or suspected allergy to peanuts or soya. Testosterone Enantate (castor or sesame oil, brand-dependent) or a transdermal gel may be a safer alternative. Discuss with your prescriber.
What is the difference between Sustanon 250 and Testosterone Enantate?
Sustanon 250 is a four-ester blend with a staggered release, usually dosed every 3 weeks on the licensed SmPC schedule. Testosterone Enantate is a single long-ester preparation, usually dosed every 2 to 3 weeks or split into weekly doses. Both are UK-licensed. The choice is driven by prescriber preference, availability and how your bloods and symptoms respond.
How often should I inject Sustanon 250?
The licensed SmPC schedule is 1ml every 3 weeks IM. In modern UK TRT practice, many prescribers favour more frequent dosing (0.5ml every 10 days, 0.5ml weekly, or 0.25ml twice weekly) to smooth peak-to-trough variation.
Can I inject Sustanon 250 subcutaneously?
The licensed route is intramuscular only. Some clinicians use SC administration off-label for a smoother profile. This is not covered by the SmPC and should only be considered with explicit prescriber guidance.
What syringe and needle should I use?
A 1ml Luer Lock syringe (such as the Unifix 1ml Luer Lock) with a wider draw needle (21G x 1.5 inch) and a finer injection needle (23G or 25G x 1 inch). Fixed-needle insulin syringes are not suitable for drawing viscous oil-based testosterone.
How many ampoules come in a pack?
Sustanon 250 is supplied in packs of 1 or 3 x 1ml ampoules depending on the dispensing quantity. Courier Pharmacy dispenses the pack size appropriate to your prescription.
Is Sustanon 250 the same as the Sustanon used in bodybuilding?
The medicine itself is the same four-ester testosterone preparation. However, Sustanon 250 is a prescription-only medicine for men with diagnosed testosterone deficiency. We dose it at physiological replacement levels under medical supervision. Use for performance enhancement in men with normal testosterone is not a licensed indication and is not supported by Courier Pharmacy.
Does Sustanon 250 affect fertility?
Yes. Testosterone replacement suppresses the hypothalamic-pituitary-gonadal axis and reduces or stops sperm production. If you plan to father children, discuss sperm banking or alternative regimens (HCG monotherapy, HCG plus hMG) with your prescriber first.
What monitoring will I need?
BSSM 2023 UK guidelines recommend baseline, 3-month, 6-month and annual bloods. The panel covers total testosterone, free testosterone or SHBG, FBC with haematocrit, PSA, lipids and HbA1c, plus a symptom score. Your prescriber books these in with you.
Is Sustanon 250 a controlled drug?
Yes. In the UK, Sustanon 250 is a Schedule 4 Part 2 Controlled Drug (CD Anab) under the Misuse of Drugs Regulations 2001. Safe-custody and CD-register rules do not apply. Possession without a prescription is still a criminal offence.
How should I store Sustanon 250?
Room temperature below 25 degrees Celsius, upright, in the original carton to protect from light. Do not refrigerate (cold oil is hard to draw). Each ampoule is single-use, discard any residual solution after one draw.
What happens if I miss a dose?
For a 3-weekly schedule, inject the missed dose as soon as you remember and reset the schedule from that date. For a weekly or twice-weekly split schedule, skip the missed dose and continue as normal. Do not double up.
Will Sustanon 250 cause gynaecomastia?
It can, through peripheral conversion of testosterone to oestradiol by aromatase. The 3-weekly SmPC schedule, which produces an early peak, can be particularly associated with early gynaecomastia symptoms. A smoother dosing schedule often helps. An aromatase inhibitor is only considered in persistent symptomatic cases.
Can I take Sustanon 250 with other medicines?
Testosterone can interact with anticoagulants, insulin or oral hypoglycaemics, corticosteroids, cyclosporine and thyroxine. Tell your prescriber about every medicine, supplement and over-the-counter product you take.
Can I drink alcohol on Sustanon 250?
Moderate alcohol is not a contraindication. However, heavy or chronic alcohol affects liver function, mood, sleep and lipids. All of these are tracked on TRT. Keep within UK Chief Medical Officers' low-risk guidance of up to 14 units a week.
What is the difference between Sustanon 250 and Testosterone Enantate?
Sustanon 250 is a four-ester blend with a staggered release, usually dosed every 3 weeks on the licensed SmPC schedule. Testosterone Enantate is a single long-ester preparation, usually dosed every 2 to 3 weeks or split into weekly doses. Both are UK-licensed. The choice is driven by prescriber preference, availability and how your bloods and symptoms respond.
How often should I inject Sustanon 250?
The licensed SmPC schedule is 1ml every 3 weeks IM. In modern UK TRT practice, many prescribers favour more frequent dosing (0.5ml every 10 days, 0.5ml weekly, or 0.25ml twice weekly) to smooth peak-to-trough variation.
Can I inject Sustanon 250 subcutaneously?
The licensed route is intramuscular only. Some clinicians use SC administration off-label for a smoother profile. This is not covered by the SmPC and should only be considered with explicit prescriber guidance.
What syringe and needle should I use?
A 1ml Luer Lock syringe (such as the Unifix 1ml Luer Lock) with a wider draw needle (21G x 1.5 inch) and a finer injection needle (23G or 25G x 1 inch). Fixed-needle insulin syringes are not suitable for drawing viscous oil-based testosterone.
How many ampoules come in a pack?
Sustanon 250 is supplied in packs of 1 or 3 x 1ml ampoules depending on the dispensing quantity. Courier Pharmacy dispenses the pack size appropriate to your prescription.
Is Sustanon 250 the same as the Sustanon used in bodybuilding?
The medicine itself is the same four-ester testosterone preparation. However, Sustanon 250 is a prescription-only medicine for men with diagnosed testosterone deficiency. We dose it at physiological replacement levels under medical supervision. Use for performance enhancement in men with normal testosterone is not a licensed indication and is not supported by Courier Pharmacy.
Does Sustanon 250 affect fertility?
Yes. Testosterone replacement suppresses the hypothalamic-pituitary-gonadal axis and reduces or stops sperm production. If you plan to father children, discuss sperm banking or alternative regimens (HCG monotherapy, HCG plus hMG) with your prescriber first.
What monitoring will I need?
BSSM 2023 UK guidelines recommend baseline, 3-month, 6-month and annual bloods. The panel covers total testosterone, free testosterone or SHBG, FBC with haematocrit, PSA, lipids and HbA1c, plus a symptom score. Your prescriber books these in with you.
Is Sustanon 250 a controlled drug?
Yes. In the UK, Sustanon 250 is a Schedule 4 Part 2 Controlled Drug (CD Anab) under the Misuse of Drugs Regulations 2001. Safe-custody and CD-register rules do not apply. Possession without a prescription is still a criminal offence.
How should I store Sustanon 250?
Room temperature below 25 degrees Celsius, upright, in the original carton to protect from light. Do not refrigerate (cold oil is hard to draw). Each ampoule is single-use, discard any residual solution after one draw.
What happens if I miss a dose?
For a 3-weekly schedule, inject the missed dose as soon as you remember and reset the schedule from that date. For a weekly or twice-weekly split schedule, skip the missed dose and continue as normal. Do not double up.
Will Sustanon 250 cause gynaecomastia?
It can, through peripheral conversion of testosterone to oestradiol by aromatase. The 3-weekly SmPC schedule, which produces an early peak, can be particularly associated with early gynaecomastia symptoms. A smoother dosing schedule often helps. An aromatase inhibitor is only considered in persistent symptomatic cases.
Can I take Sustanon 250 with other medicines?
Testosterone can interact with anticoagulants, insulin or oral hypoglycaemics, corticosteroids, cyclosporine and thyroxine. Tell your prescriber about every medicine, supplement and over-the-counter product you take.
Can I drink alcohol on Sustanon 250?
Moderate alcohol is not a contraindication. However, heavy or chronic alcohol affects liver function, mood, sleep and lipids. All of these are tracked on TRT. Keep within UK Chief Medical Officers' low-risk guidance of up to 14 units a week.
What is Sustanon?
Sustanon is the brand name for a UK-licensed four-ester testosterone depot injection manufactured by Aspen Pharma. Each 1ml ampoule delivers 250mg of testosterone across propionate, phenylpropionate, isocaproate and decanoate esters.
Where can I buy Sustanon 250 in the UK?
From a UK-registered pharmacy with a valid UK prescription. Courier Pharmacy dispenses Sustanon 250 following a BSSM-aligned TRT consultation. Purchase without a UK prescription is a criminal offence under the Misuse of Drugs Act 1971.
Where to buy Sustanon 250
A UK-registered pharmacy with a valid UK prescription is the only legal route. Our TRT consultation pathway at courierpharmacy.co.uk/trt covers new patients. Established TRT patients can upload an existing prescription at checkout.
Sustanon 250 where to buy
From a UK-registered pharmacy against a valid UK prescription. Courier Pharmacy supplies the 1ml ampoule following a BSSM-aligned consultation. No supply is permitted without a UK prescription.
How often to inject Sustanon 250?
The licensed SmPC schedule is 1ml every 3 weeks IM. Many UK prescribers now favour more frequent dosing (0.5ml every 10 days, 0.5ml weekly, or 0.25ml twice weekly) to smooth peak-to-trough variation.
Is Sustanon good for TRT?
Yes. Sustanon 250 is a UK-licensed TRT option backed by decades of clinical use. The four-ester blend produces a staggered release of testosterone. BSSM 2023 UK guidelines support it as a first-line long-acting injectable for male hypogonadism.
How much is Sustanon 250 cost?
UK private pricing varies by pack size (1 or 3 ampoules) and dispensing fees. See the live product page at courierpharmacy.co.uk for current pricing. Advertising prices for Controlled Drugs sits under UK regulatory restrictions.
What does Sustanon 250 do to your body?
It replaces missing testosterone in men with hypogonadism. The hormone supports libido, erectile function, mood, energy, bone density, lean body mass and red cell production once levels sit in the physiological range.
Is 1ml of Sustanon a week enough?
1ml per week equals 250mg, above the typical BSSM UK starting dose of 100mg to 150mg per week. Your prescriber sets the exact dose from your bloods, usually targeting mid-to-upper normal total testosterone.
Is Sustanon 250 good for TRT?
Yes, Sustanon 250 is a widely-used UK-licensed TRT option. The four-ester blend covers both early-week and late-week testosterone levels on a 3-weekly schedule, though many men prefer split dosing for smoother levels.
Where can I buy Sustanon 250?
From a UK-registered pharmacy against a valid UK prescription. Courier Pharmacy dispenses it following a documented BSSM-aligned consultation. Patients outside the UK should seek supply through their local prescriber.
Where to get Sustanon 250
Through a BSSM-aligned UK TRT consultation and a valid UK prescription from a UK-registered prescriber. There is no legal non-prescription route in the UK.
How long does Sustanon take to work?
Libido and mood often improve within 2 to 4 weeks. Energy and body-composition changes build over 6 to 12 weeks. Full stabilisation at your target testosterone level typically occurs by 6 months.
How to inject Sustanon 250
Snap the ampoule, draw with a 21G x 1.5 inch needle, swap to a 23G or 25G x 1 inch injection needle. Inject deep IM into the ventrogluteal or vastus lateralis at 90 degrees, deliver slowly over 10 to 20 seconds. Only inject after a prescriber or nurse has taught you the technique.
How to buy Sustanon 250
Complete a TRT consultation at courierpharmacy.co.uk/trt, submit baseline bloods, and if clinically appropriate receive a private prescription. We dispense the ampoules by signed-for tracked UK delivery.
How much Sustanon per week?
UK TRT typically runs at 100mg per week. Your prescriber sets the exact weekly dose based on your bloods, haaematocrit and symptom score. We adjust at the 3-month and 6-month reviews.
Can Sustanon 250 be used for TRT?
Yes. Sustanon 250 is a UK-licensed TRT product with full MHRA oversight and a long clinical track record. BSSM 2023 lists it as one of three first-line long-acting injectable options.
What is Sustanon used for?
Testosterone replacement therapy (TRT) in men with clinically and biochemically confirmed testosterone deficiency (hypogonadism). It is not prescribed for performance enhancement, body composition goals, or men with normal testosterone.
Can Sustanon be injected subcutaneously?
The licensed route is intramuscular only. Some clinicians use SC administration off-label for a smoother profile. This is outside the SmPC and should only be considered with explicit prescriber guidance.
How much Sustanon 250 should I take?
Your prescriber sets the exact dose. Typical UK TRT runs at 100mg to 150mg per week, titrated to your bloods and symptoms. Doses above 250mg per week sit outside typical replacement therapy.
What does Sustanon do?
It raises testosterone to the physiological range in men with hypogonadism. Benefits typically include improved libido, erectile function, mood, energy, bone density and lean body mass over 3 to 6 months of consistent dosing.
How long for Sustanon to kick in?
Early effects (libido, mood lift) often appear within 2 to 4 weeks. Energy and strength changes build over 6 to 12 weeks. Steady state across the cycle takes 6 to 12 weeks of regular dosing.
How long does Sustanon stay in your system?
The decanoate ester has a half-life of 7 to 9 days, so testosterone from a single dose stays measurable for 3 to 4 weeks. Full clearance from testing panels is typically 4 to 6 weeks, depending on dose.
Where to inject Sustanon 250
Into deep intramuscular tissue, either the ventrogluteal (upper outer buttock) or vastus lateralis (outer upper thigh) in most adults. Rotate sites each dose to prevent injection-site reactions and lipohypertrophy.
How to inject Sustanon
Snap the ampoule, draw with a wide-bore needle (21G x 1.5 inch), swap to a finer injection needle (23G or 25G x 1 inch). Inject deep IM at 90 degrees, deliver slowly. Only inject after a prescriber or nurse has taught you the technique.
How long does Sustanon 250 take to work?
Early benefit at 2 to 4 weeks (libido, mood), full stabilisation by 6 months. Review bloods at 3 months, 6 months, then annually.
How to give Sustanon injection
Follow the technique your prescriber or practice nurse has taught you. The licensed route is deep intramuscular injection. Snap the ampoule, draw with a wide needle, swap to a fine injection needle, inject slowly, dispose of sharps in a yellow bin.
How long does Sustanon take to work bodybuilding?
Sustanon 250 is a prescription-only medicine for men with diagnosed testosterone deficiency, not for bodybuilding. Use for performance enhancement is not a licensed indication and is not supported by Courier Pharmacy, and may be a criminal offence under the Misuse of Drugs Act 1971.
Sustanon 250 how often to inject?
Licensed SmPC schedule is 1ml every 3 weeks IM. Modern UK TRT practice uses 0.5ml every 10 days, 0.5ml weekly, or 0.25ml twice weekly for smoother levels. Your prescriber picks the schedule from your bloods.
What's in Sustanon 250?
Four testosterone esters (propionate, phenylpropionate, isocaproate, decanoate) totalling 250mg per 1ml ampoule, suspended in arachis (peanut) oil with benzyl alcohol preservative. The peanut oil content means it is contraindicated in anyone with a peanut or soya allergy.
How long does Sustanon 250 stay in your system?
Up to 3 to 4 weeks after a single injection, driven by the decanoate component. Full clearance from blood tests is typically 4 to 6 weeks. Elimination is slower with repeated dosing.
Is Sustanon safe?
At replacement doses with proper monitoring, long-term use has an acceptable safety profile backed by the TRAVERSE trial (NEJM 2023). Risks include erythrocytosis, acne, mood changes, fertility suppression and worsening of pre-existing prostate cancer. Peanut allergy is a hard contraindication.
What is Sustanon injection used for?
Testosterone replacement therapy in men with testosterone deficiency (hypogonadism). It is prescribed as part of a monitored TRT programme, with baseline and follow-up bloods against the BSSM 2023 framework.
What is test Sustanon?
"Test Sustanon" is slang for Sustanon 250, a testosterone depot injection. "Test" is short for testosterone. The medicine is a four-ester testosterone preparation, UK-licensed for male hypogonadism.
How many ml of Sustanon 250 per week?
UK TRT typically runs at 0.4ml per week when split (equivalent to 100mg). The licensed SmPC schedule is 1ml every 3 weeks, which averages to around 0.33ml per week.
Where to inject Sustanon
Into deep muscle, either the ventrogluteal site or the vastus lateralis. These are the standard adult IM sites. Rotate between left and right at each dose.
What is testosterone Sustanon?
Sustanon is a brand of testosterone injection. The medicine itself is a mix of four testosterone esters in oil, which release testosterone over about 3 weeks after a single IM injection.
How to take Sustanon 250
Sustanon 250 is for intramuscular injection, not oral use. Snap the ampoule, draw with a 21G needle, swap to a finer injection needle, inject deep IM at 90 degrees. Only inject after a prescriber or nurse has taught you the technique.
How much Sustanon 250 should I take a week?
Typical UK TRT doses are 100mg to 150mg per week. Your prescriber sets the exact weekly dose from your bloods, haematocrit and symptom score. The dose is reviewed at 3 months, 6 months, then annually.
What is Sustanon 250 used for?
Testosterone replacement therapy (TRT) in men with clinically and biochemically confirmed hypogonadism, under the UK licensed indication. The product is not prescribed for performance enhancement or men with normal testosterone.
What is the half life of Sustanon 250?
The four esters have different half-lives: propionate around 0.8 days, phenylpropionate around 1.5 days, isocaproate around 4 days, decanoate around 7 to 9 days. The blend produces a staggered release lasting around 3 weeks.
How much is 1ml of Sustanon 250?
1ml of Sustanon 250 contains 250mg of testosterone across four esters. UK private pricing varies, see the live product page at courierpharmacy.co.uk for current pricing per ampoule.
How long does Sustanon 250 take to kick in?
First effects (libido, mood) typically within 2 to 4 weeks. Energy, strength and body-composition changes build over 6 to 12 weeks. Steady-state blood levels take 6 to 12 weeks of consistent dosing.
Disclaimer
Educational content, not a substitute for medical advice. This page is published by Courier Pharmacy as educational product information. It is not personalised medical advice, and it does not replace a consultation with your prescriber, pharmacist or GP. Always follow the dose and schedule written on your prescription, and the instructions your prescriber has given you for your particular circumstances. If anything on this page contradicts what your prescriber has told you, follow your prescriber.
UK-licensed Patient Information Leaflet is the authoritative source. Sustanon 250 is a UK-licensed medicine under MA holder Aspen Pharma Trading Limited. The Patient Information Leaflet (PIL) supplied in the carton is the authoritative patient-facing document for the specific pack you receive. Always read the PIL before use.
Prescription-only and Controlled Drug status. Sustanon 250 is a prescription-only medicine (POM) under the Human Medicines Regulations 2012 and a Schedule 4 Part 2 Controlled Drug (CD Anab) under the Misuse of Drugs Regulations 2001. Possession without a valid prescription is a criminal offence. Do not share, sell or supply this medicine to anyone else, do not import it personally without a UK prescription, and keep it secured in your own home.
Peanut and benzyl alcohol allergy warning. Sustanon 250 contains arachis (peanut) oil and benzyl alcohol. Do not use if you have a known or suspected allergy to peanuts, soya or benzyl alcohol. If a severe allergic reaction occurs after injection, call 999.
Sharps and disposal responsibility. By using this medicine you accept legal responsibility under the UK Health and Safety (Sharp Instruments in Healthcare) Regulations 2013 and the Hazardous Waste Regulations 2005 for safe sharps disposal. Never place used needles, syringes or empty glass ampoules in household waste or recycling. Use a UK-standard yellow sharps bin and arrange collection through your local authority.
Not for performance enhancement. Sustanon 250 is prescribed for men with clinically and biochemically confirmed testosterone deficiency, in line with the BSSM 2023 UK Guidelines. Use for sporting performance, body-composition goals in men with normal testosterone, or any non-medical indication is not a licensed use and is not supported by Courier Pharmacy. Such use may be a criminal offence under the Misuse of Drugs Act 1971.
References
- Ahsan, S. (2026) A comprehensive timeline: the development of testosterone replacement therapy, Courier Pharmacy. Available at: https://courierpharmacy.co.uk/a-comprehensive-timeline-the-development-of-testosterone-replacement-therapy/ (Accessed: 10 October 2026).
- Hackett, G. (2023) A practical guide to the assessment and management of testosterone deficiency. Trends in Urology & Men’s Health. Available at: https://bssm.org.uk/wp-content/uploads/2023/08/Trends-Urol-Men-s-Health-2023-Hackett-A-practical-guide-to-the-assessment-and-management-of-testosterone-deficiency-1.pdf (Accessed: 10 October 2026).
- UK Legislation (2001, amended). The Misuse of Drugs Regulations 2001, Schedule 4 Part 2 (CD Anab). Available at: https://www.legislation.gov.uk/uksi/2001/3998/schedule/4/made
- British National Formulary (accessed 2026). Testosterone. Available at: https://bnf.nice.org.uk/drugs/testosterone/
- NHS (2026) Male menopause. NHS. Available at: https://www.nhs.uk/conditions/male-menopause/ (Accessed: 10 October 2026).
- Spratt DI, Stewart II, Savage C, et al. (2017). Subcutaneous Injection of Testosterone Is an Effective and Preferred Alternative to Intramuscular Injection. Journal of Clinical Endocrinology and Metabolism, 102(7), pp.2349-2355. Available at: https://academic.oup.com/jcem/article/102/7/2349/3760395
- Medicines and Healthcare products Regulatory Agency. Yellow Card scheme. Available at: https://yellowcard.mhra.gov.uk
- Electronic Medicines Compendium (emc) (2026) [Summary of Product Characteristics for product 5373]. Available at: https://www.medicines.org.uk/emc/product/5373/smpc (Accessed: 11 October 2026).
- British National Formulary (accessed 2026). Testosterone. Available at: https://bnf.nice.org.uk/drugs/testosterone/
- UK Legislation (2001, amended). The Misuse of Drugs Regulations 2001, Schedule 4 Part 2 (CD Anab). Available at: https://www.legislation.gov.uk/uksi/2001/3998/schedule/4/made
- UK Legislation (1971). Misuse of Drugs Act 1971. Available at: https://www.legislation.gov.uk/ukpga/1971/38/contents
- UK Legislation (2012). The Human Medicines Regulations 2012. Available at: https://www.legislation.gov.uk/uksi/2012/1916/contents/made
- Medicines and Healthcare products Regulatory Agency. Yellow Card scheme. Available at: https://yellowcard.mhra.gov.uk
